保田壮一郎 (Soichiro YASUDA) - マイポータル

基本情報

所属: 国際医療福祉大学医学部

J-GLOBAL ID: 201801017355801908
researchmap会員ID: B000327391

研究分野

ライフサイエンス / 循環器内科学 /

論文

THE HUMAN ETHER-A-GO-GO-RELATED GENE (hERG) CURRENT INHIBITION SELECTIVELY PROLONGS ACTION POTENTIAL OF MIDMYOCARDIAL CELLS TO AUGMENT TRANSMURAL DISPERSION

C. Yasuda, S. Yasuda, H. Yamashita, J. Okada, T. Hisada, S. Sugiura

JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY 66(4) 599-607 2015年8月査読有り
Diastolic dysfunction and thin filament dysregulation resulting from excitation-contraction uncoupling in a mouse model of restrictive cardiomyopathy

Jennifer Davis, Soichiro Yasuda, Nathan J. Palpant, Joshua Martindale, Tamara Stevenson, Kimber Converso, Joseph M. Metzger

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 53(3) 446-457 2012年9月査読有り
Distinct pathophysiological mechanisms of cardiomyopathy in hearts lacking dystrophin or the sarcoglycan complex

DeWayne Townsend, Soichiro Yasuda, Elizabeth McNally, Joseph M. Metzger

FASEB JOURNAL 25(9) 3106-3114 2011年9月査読有り
Chronic administration of membrane sealant prevents severe cardiac injury and ventricular dilatation in dystrophic dogs

DeWayne Townsend, Immanuel Turner, Soichiro Yasuda, Joshua Martindale, Jennifer Davis, Michael Shillingford, Joe N. Kornegay, Joseph M. Metzger

JOURNAL OF CLINICAL INVESTIGATION 120(4) 1140-1150 2010年4月査読有り
Cardiac consequences to skeletal muscle-centric therapeutics for Duchenne muscular dystrophy.

Townsend D, Yasuda S, Chamberlain J, Metzger JM

Trends Cardiovasc Med 19 50-55 2009年2月査読有り
Molecular Cardiology in Translation: Gene, Cell and Chemical-Based Experimental Therapeutics for the Failing Heart

Immanuel Turner, Fikru Belema-Bedada, Joshua Martindale, DeWayne Townsend, Wang Wang, Nathan Palpant, So-chiro Yasuda, Matthew Barnabei, Ekaterina Fomicheva, Joseph M. Metzger

JOURNAL OF CARDIOVASCULAR TRANSLATIONAL RESEARCH 1(4) 317-327 2008年12月査読有り
Emergent dilated cardiomyopathy caused by targeted repair of dystrophic skeletal muscle

DeWayne Townsend, Soichiro Yasuda, Sheng Li, Jeffrey S. Chamberlain, Joseph M. Metzger

MOLECULAR THERAPY 16(5) 832-835 2008年5月査読有り
Non-canonical Wnt signaling enhances differentiation of Sca1(+)/c-kit(+) adipose-derived murine stromal vascular cells into spontaneously beating cardiac myocytes

Nathan J. Palpant, So-ichiro Yasuda, Ormond MacDougald, Joseph M. Metzger

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 43(3) 362-370 2007年9月査読有り
Cardiac Transgenic and gene transfer strategies converge to support an important role for troponin I in regulating relaxation in cardiac myocytes

So-ichiro Yasuda, Pierre Coutu, Sakthivel Sadayappan, Jeffrey Robbins, Joseph M. Metzger

CIRCULATION RESEARCH 101(4) 377-386 2007年8月査読有り
KCNQ potassium channel mutations cause cardiac arrhythmias in Drosophila that mimic the effects of aging

Karen Ocorr, Nick L. Reeves, Robert J. Wessells, Martin Fink, H. -S. Vincent Chen, Takeshi Akasaka, Soichiro Yasuda, Joseph M. Metzger, Wayne Giles, James W. Posakony …

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 104(10) 3943-3948 2007年3月査読有り
Cardiomyopathy of Duchenne muscular dystrophy: pathogenesis and prospect of membrane sealants as a new therapeutic approach.

Townsend D, Yasuda S, Metzger J

Expert Rev Cardiovasc Ther 5 99-109 2007年1月査読有り
Histidine button engineered into cardiac troponin I protects the ischemic and failing heart

SM Day, MV Westfall, EV Fomicheva, K Hoyer, S Yasuda, NC La Cross, LG D'Alecy, JS Ingwall, JM Metzger

NATURE MEDICINE 12(2) 181-189 2006年2月査読有り
Carbon fiber technique for the investigation of single-cell mechanics in intact cardiac myocytes

Seiryo Sugiura, Satoshi Nishimura, Soichiro Yasuda, Yumiko Hosoya, Kaoru Katoh

NATURE PROTOCOLS 1(3) 1453-1457 2006年査読有り
Dystrophic heart failure blocked by membrane sealant poloxamer

S Yasuda, D Townsend, DE Michele, EG Favre, SM Day, JM Metzger

NATURE 436(7053) 1025-1029 2005年8月査読有り
Single cell mechanics of rat cardiomyocytes under isometric, unloaded, and physiologically loaded conditions

S Nishimura, S Yasuda, M Katoh, KP Yamada, H Yamashita, Y Saeki, K Sunagawa, R Nagai, T Hisada, S Sugiura

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY 287(1) H196-H202 2004年7月査読有り
Role of Ca2+ in determining the rate of tension development and relaxation in rat skinned myocardium

Y Saeki, T Kobayashi, S Yasuda, S Nishimura, S Sugiura, H Yamashita, H Sugi

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 36(3) 371-380 2004年3月査読有り
Myosin light chain isoforms modify force-generating ability of cardiac myosin by changing the kinetics of actin-myosin interaction

H Yamashita, S Sugiura, H Fujita, S Yasuda, R Nagai, Y Saeki, K Sunagawa, H Sugi

CARDIOVASCULAR RESEARCH 60(3) 580-588 2003年12月査読有り
Unloaded shortening increases peak of Ca2+ transients but accelerates their decay in rat single cardiac myocytes.

Yasuda S, Sugiura S, Yamashita H, Nishimura S, Saeki Y, Momomura S, Katoh K, Nagai R, Sugi H

Am J Physiol Heart Circ Physiol 285 H470-475 2003年8月査読有り
Measurement of force developed by a single cardiac myocyte using novel carbon fibers.

Sugiura S, Yasuda S, Yamashita H, Kato K, Saeki Y, Kaneko H, Suda Y, Nagai R, Sugi H

Adv Exp Med Biol 538 381-386 2003年査読有り
A novel method to study contraction characteristics of a single cardiac myocyte using carbon fibers.

Yasuda SI, Sugiura S, Kobayakawa N, Fujita H, Yamashita H, Katoh K, Saeki Y, Kaneko H, Suda Y, Nagai R …

Am J Physiol Heart Circ Physiol 281 H1442-1446 2001年9月査読有り

もっとみる

産業財産権

United States Patent 7,846,426 Compositions and methods for treating and preventing cardiomyopathy and heart disease

Soichiro YASUDA