Naito Yasuhiro

Profile Information

Affiliation: Professor, Faculty of Environment and Information Studies, Keio University

Degree: M. D., Ph. D(Mar, 1998, Hamamatsu University School of Medicine)

Researcher number: 50327714
J-GLOBAL ID: 200901099467490898
researchmap Member ID: 1000364245

External link: http://www.e-cell.org

Research Areas

Research History

Apr, 2002 - Mar, 2003

大学専任講師(有期)(環境情報学部)
Apr, 2001 - Mar, 2002

大学専任講師(有期)(環境情報学部)
Apr, 2000 - Mar, 2001

大学助手(嘱託)(環境情報学部)
Apr, 1999 - Mar, 2000

東京大学 ,COE研究員
Jun, 1998 - Mar, 1999

東京大学医科学研究所 ,技官
Apr, 1998 - May, 1998

東京大学医科学研究所 ,客員研究員

Education

Mar, 1998

Graduate School, Division of Medicine, Hamamatsu University School of Medicine
Mar, 1998 - Mar, 1998

Graduate School, Division of Medicine, Hamamatsu University School of Medicine
Mar, 1994 - Mar, 1994

Faculty of Medicine, Hamamatsu University School of Medicine

Papers

Developmental changes in the balance of glycolytic ATP production and oxidative phosphorylation in ventricular cells: A simulation study

Hitomi I. Sano, Tamami Tokia, Yasuhiro Naito, Masaru Tomita

JOURNAL OF THEORETICAL BIOLOGY, 419 269-277, Apr, 2017 Peer-reviewed
Combination of Quantitative Changes in Ionic Components to Enhance the Contractile Force during T-tubule Development

Maiko Wakita, Hitomi I. Sano, Yasuhiro Naito, Masaru Tomita

2016 COMPUTING IN CARDIOLOGY CONFERENCE (CINC), VOL 43, 43 1093-1096, 2016 Peer-reviewed
Simulation Study on the Balance of Glycolytic ATP Production and Oxidative Phosphorylation in Embryonic and Adult Ventricular Cells

Hitomi I. Sano, Yasuhiro Naito, Masaru Tomita

2016 COMPUTING IN CARDIOLOGY CONFERENCE (CINC), VOL 43, 43 249-252, 2016 Peer-reviewed
Sensitivity analysis of ectopic electrical activity in the pulmonary vein myocardium

Hitomi I. Sano, Yuichiro Tanaka, Yasuhiro Naito, Masaru Tomita

Computing in Cardiology, 42 861-864, Feb 16, 2015 Peer-reviewed
Sensitivity Analysis of Ectopic Electrical Activity in the Pulmonary Vein Myocardium

Hitomi I. Sano, Yuichiro Tanaka, Yasuhiro Naito, Masaru Tomita

2015 COMPUTING IN CARDIOLOGY CONFERENCE (CINC), 42 861-864, 2015 Peer-reviewed
Modeling and Simulation of Developmental Changes in Contractile Apparatus of Ventricular Cells

Mao Takiguchi, Tamami Toki, Hitomi I. Sano, Yasuhiro Naito, Masaru Tomita

2015 COMPUTING IN CARDIOLOGY CONFERENCE (CINC), 42 1097-1100, 2015 Peer-reviewed
Survival of HER2-positive primary breast cancer patients treated by neoadjuvant chemotherapy plus trastuzumab: a multicenter retrospective observational study (JBCRG-C03 study)

M. Takada, H. Ishiguro, S. Nagai, S. Ohtani, H. Kawabata, Y. Yanagita, Y. Hozumi, C. Shimizu, S. Takao, N. Sato …

BREAST CANCER RESEARCH AND TREATMENT, 145(1) 143-153, May, 2014 Peer-reviewed
Predictive factors for pathologic complete response and disease-free survival after neoadjuvant chemotherapy with trastuzumab: A multicenter retrospective observational study in patients with HER2-positive primary breast cancer (JBCRG-C03 study)

M. Takada, H. Ishiguro, S. Nagai, S. Ohtani, H. Kawabata, Y. Yanagita, Y. Hozumi, C. Shimizu, S. Takao, N. Sato …

CANCER RESEARCH, 73, Dec, 2013 Peer-reviewed
Contribution of quantitative changes in individual ionic current systems to the embryonic development of ventricular myocytes: a simulation study

Chikako Okubo, Hitomi I. Sano, Yasuhiro Naito, Masaru Tomita

JOURNAL OF PHYSIOLOGICAL SCIENCES, 63(5) 355-367, Sep, 2013 Peer-reviewed
Development of web tools to predict pathological response to neoadjuvant chemotheraphy and axillary lymph node metastasis in breast cancer patients

Sugimoto, M, Takada, M, Ohno, S, Kuroi, K, Sato, N, Bando, H, Masuda, N, Iwata, H, Kondo, M, Sasano, H …

European Jouranl of Cancer, 49(Supplement 1) S6-7, 2013 Peer-reviewed
Predictions of the pathological response to neoadjuvant chemotherapy in patients with primary breast cancer using a data mining technique

M. Takada, M. Sugimoto, S. Ohno, K. Kuroi, N. Sato, H. Bando, N. Masuda, H. Iwata, M. Kondo, H. Sasano …

BREAST CANCER RESEARCH AND TREATMENT, 134(2) 661-670, Jul, 2012
Prediction of axillary lymph node metastasis in primary breast cancer patients using a decision tree-based model

Masahiro Takada, Masahiro Sugimoto, Yasuhiro Naito, Hyeong-Gon Moon, Wonshik Han, Dong-Young Noh, Masahide Kondo, Katsumasa Kuroi, Hironobu Sasano, Takashi Inamoto …

BMC MEDICAL INFORMATICS AND DECISION MAKING, 12, Jun, 2012
Utility of a Prediction Model for Axillary Lymph Node Metastasis in Patients with Primary Breast Cancer using A Decision-tree Algorithm

M. Takada, M. Sugimoto, Y. Naito, H. Moon, W. Han, D. Noh, M. Kondo, K. Kuroi, H. Sasano, T. Inamoto …

ANNALS OF SURGICAL ONCOLOGY, 19 S80-S80, Feb, 2012
Development of a Prediction Model for Treatment Response to Neoadjuvant Chemotherapy in Patients with Primary Breast Cancer Using a Decision-tree Algorithm

M. Toi, M. Takada, M. Sugimoto, Y. Naito, H. Bando, H. Iwata, K. Kuroi, N. Masuda, S. Ohno, N. Sato …

ANNALS OF SURGICAL ONCOLOGY, 19 S69-S69, Feb, 2012
Role of Na+-Ca2+ Exchange in Neonatal and Adult Ventricular Cells: A Simulation Study

Hitomi I. Sano, Yasuhiro Naito, Masaru Tomita

2012 COMPUTING IN CARDIOLOGY (CINC), VOL 39, 39 877-880, 2012 Peer-reviewed
抗がん剤効果予測による乳がん患者の再発リスク抑制と毒性軽減および医療経済負担低減に関する検証的研究乳癌のリンパ節転移と術前化学療法の効果予測システムの開発

HNAITO YASUHIRO, HR

抗がん剤効果予測による乳がん患者の再発リスク抑制と毒性軽減および医療経済負担低減に関する検証的研究平成23年度研究報告書, 31-37, 2012
Computational assessment of insulin secretion and insulin sensitivity from 2-h oral glucose tolerance tests for clinical use for type 2 diabetes

Masayoshi Seike, Takeo Saitou, Yasuhiro Kouchi, Takeshi Ohara, Munehide Matsuhisa, Kazuhiko Sakaguchi, Koji Tomita, Keisuke Kosugi, Atsunori Kashiwagi, Masato Kasuga …

JOURNAL OF PHYSIOLOGICAL SCIENCES, 61(4) 321-330, Jul, 2011
抗がん剤効果予測による乳がん患者の再発リスク抑制と毒性軽減および医療経済負担低減に関する検証的研究乳癌の治療効果予測のための数理アルゴリズム開発法の検討

HNAITO YASUHIRO, HR

抗がん剤効果予測による乳がん患者の再発リスク抑制と毒性軽減および医療経済負担低減に関する検証的研究平成22年度研究報告書 ), 26-34, 2011
Predictive value of CD24 and CD44 for neoadjuvant chemotherapy response and prognosis in primary breast cancer patients

Kazumi Horiguchi, Masakazu Toi, Shin-Ichiro Horiguchi, Masahiro Sugimoto, Yasuhiro Naito, Yukiko Hayashi, Takayuki Ueno, Shinji Ohno, Nobuaki Funata, Katsumasa Kuroi …

Journal of Medical and Dental Sciences, 57(2) 165-175, Jun, 2010
データ駆動の乳がん診断支援・病態予測

HNAITO YASUHIRO, HR

がん分子標的治療, 8(2) 143-148, May, 2010

Misc.

酵母フェロモンシグナル伝達を利用した遺伝子回路の構築と数理モデル化

大沼泰秀, 冨田勝, 谷内江望, 内藤泰宏

生命科学系学会合同年次大会, 2017年度 [2P-1317], Dec, 2017
Simulation of energy metabolism in fetal and adult ventricular cells

Tamami Toki, Chikako Okubo, Hitomi Sano, Yasuhiro Naito, Masaru Tomita

JOURNAL OF PHYSIOLOGICAL SCIENCES, 63 S138-S138, 2013
データマイニングを用いた新しい術前化学療法の治療効果予測モデルの開発

高田正泰, 杉本昌弘, 大野真司, 黒井克昌, 佐藤信昭, 坂東裕子, 増田慎三, 岩田広治, 近藤正英, 笹野公伸 …

日本乳癌学会総会プログラム抄録集, 20回 303-303, May, 2012
Construction of a self-organizing model for valve pattern formation in diatoms

ISHIDA Kana, NAITO Yasuhiro, TOMITA Masaru

26(2) 263-263, Dec 1, 2011
Predicting Risk of Axillary Lymph Node Metastasis: A Novel, Decision Tree-Based Approach That Can Handle Incomplete Datasets

M. Takada, M. Sugimoto, Y. Naito, M. Kondo, K. Kuroi, T. Inamoto, M. Tomita, M. Toi

CANCER RESEARCH, 70, Dec, 2010
Model-Based Assessment of beta-Cell Function, Peripheral Insulin Sensitivity, and Splanchnic Glucose Output for Individualized Therapeutic Strategies for Type 2 Diabetes

Masayoshi Seike, Takeo Saitou, Yasuhiro Kouchi, Yasuhiro Naito, Hiromu Nakajima

DIABETES, 58 A619-A619, Jun, 2009
乳癌の遠隔転移診断決定木を用いた原発性乳癌における腋窩リンパ節転移予測と予測因子の探索

高田正泰, 杉本昌弘, 内藤泰宏, 黒井克昌, 冨田勝, 戸井雅和

日本乳癌学会総会プログラム抄録集, 17回 195-195, Jun, 2009

Books and Other Publications

シミュレーション辞典

HYasuhiro Naito, HR (Role: Contributor, 細胞シミュレーション)

コロナ社, Feb 27, 2012 (ISBN: 9784339024586)
E-CELL System: Basic Concepts And Applications

HYasuhiro NAITO, HR

Eurekah.Com Inc, 2004 (ISBN: 1587062313)

Presentations

Combination of quantitative changes in ionic components to enhance the contractile force in embryonic ventricular cells

HHitomi Sano, HR#HMaiko Wakita, HR#HYasuhiro Naito, HR#HMasaru Tomita, HR

The 94rd Annual Meeting of the Physiological Society of Japan, Mar 30, 2017, The Physiological Society of Japan
Simulation Study on Balance of Glycolytic ATP Production and Oxidative Phosphorylation in Embryonic and Adult Ventricular Cells

HHitomi Sano, HR#HYasuhiro Naito, HR#HMasaru Tomita, HR

Computing in Cardiology 2016, Sep 13, 2016, Computing in Cardiology
Combination of Quantitative Changes in Ionic Components to Enhance the Contractile Force during T-tubule Development

HMaiko Wakita, HR#HHitomi Sano, HR#HYasuhiro Naito, HR#HMasaru Tomita, HR

Computing in Cardiology 2016, Sep 13, 2016, Computing in Cardiology
A mathematical model of genetic evolution under irregularly changing environments: increases of dispensable genes and the number of genes.

HHideto Mori, HR#HYasuhiro Naito, HR#HMasaru Tomita, HR

18th Annual Meeting of the Society of Evolutionary Studies, Japan, Aug 25, 2016, 日本進化学会
Dynamic simulation of energy metabolism in fetal guinea pig ventricular cells

HHitomi Sano, HR#HTamami Toki, HR#HMao Takiguchi, HR#HYasuhiro Naito, HR#HMasaru Tomita, HR

The 93rd Annual Meeting of the Physiological Society of Japan, Mar 23, 2016, The Physiological Society of Japan
Developmental changes in ventricular cell contraction: a simulation study

HMaiko Wakita, HR#HHitomi Sano, HR#HYasuhiro Naito, HR#HMasaru Tomita, HR

The 93rd Annual Meeting of the Physiological Society of Japan, Mar 23, 2016, The Physiological Society of Japan
Does Metabolic Heterogeneity in Liver Optimize the Efficiency of Ammonia Elimination? : a Simulation Study

HShoko Jinno, HR#HYasuhiro Naito, HR#HMasaru Tomita, HR

The 93rd Annual Meeting of the Physiological Society of Japan, Mar 23, 2016, The Physiological Society of Japan
生命現象モデルをin silico/in vivo でつくってうごかす

HYasuhiro Naito, HR

東邦大学薬学部第34回生命科学シンポジウム, Oct 7, 2015, Toho University Invited
Evolution of metabolic zonation in liver nitrogen metabolism: a simulation study

HYasuhiro Naito, HR#HKazuto Yamada, HR#HMaseru Tomita, HR

16th Annual Meeting of Society of Evolutionary Studies, Japan, Aug 21, 2014, 日本進化学会
心筋細胞の発生過程による興奮収縮連関の変化についてのシミュレーション

佐野ひとみ, 土岐珠未, 青木莉子, H内藤泰宏, HR, 冨田勝

第91回日本生理学会大会, Mar 18, 2014, 日本生理学会
Predictive factors for pathologic complete response and disease-free survival after neoadjuvant chemotherapy with trastuzumab: a multicenter retrospective observational study in patients with HER2-positive primary breast cancer (JBCRG-C03 study)

Masahiro Takada, Hiroshi Ishiguro, Shigenori Nagai, Shoichiro Ohtani, Hidetaka Kawabata, Yasuhiro Yanagita, Yasuo Hozumi, Chikako Shimizu, Shintaro Takao, Nobuaki Sato, Yoshimasa Kosaka, Yasuaki Sagara, Hiroji Iwata, Shinji Ohno, Katsumasa Kuroi, Norikazu Masuda, Hiroyasu Yamashiro, Masahiro Sugimoto, Masahide Kondo, HYasuhiro Naito, HR, Hironobu Sasano, Takashi Inamoto, Satoshi Morita, Masakazu Toi

SABCS 2013 (The 36th San Antonio Breast Cancer Symposium), Dec 10, 2013, Cancer Therapy & Research Center at UT Health Science Center San Antonio
肝アンモニア代謝の不均質構造を最適化しているのは何か:コンピュータシミュレーションと進化的アルゴリズムを用いた考察

山田一翔, H内藤泰宏, HR, 冨田勝

日本分子生物学会第36回年会, Dec 5, 2013, 日本分子生物学会
コンピュータシミュレーションによる心室筋細胞の胎生・成体期におけるエネルギー産生機構の探求

土岐珠未, 佐野ひとみ, H内藤泰宏, HR, 冨田勝

日本分子生物学会第36回年会, Dec 4, 2013, 日本分子生物学会
Simulation of developmental changes in energy metabolism between fetal and adult ventricular cells

T. Toki, H.I. Sano, C. Okubo, HY. Naito, HR, M. Tomita

IUPS 2013 (The 37th International Congress of Physiological Sciences), Jul 21, 2013, The Physiological Society
Simulation of developmental change in structure of transverse tubules and intracellular Ca²⁺ dynamics using cardiac ventricular cell models

R. Aoki, H.I. Sano, C. Okubo, HY. Naito, HR, M. Tomita

IUPS 2013 (The 37th International Congress of Physiological Sciences), Jul 21, 2013, The Physiological Society
Exploring the design space for membrane excitation of cardiomyocyte

HYasuhiro Naito, Masaru Tomita, HR

第32回日本分子生物学会年会, Dec 12, 2009, 日本分子生物学会
細胞内アンモニア代謝モデルに基づく組織レベル代謝区域化のシミュレーション

H Yasuhiro Naito, Hiromu Nakajima, HR

第82回日本生化学会大会, Oct 22, 2009, 日本生化学会 Invited
Optimization of Ammonia Metabolism Energetics in Liver Lobule: A Simulation Study

HYasuhiro Naito, Hiromu, Nakajima, Masaru Tomita, HR

Congress of the International Union of Physiological Sciences, Jul 29, 2009
SIMULATION OF DEVELOPMENTAL CHANGES IN ACTION POTENTIALS WITH VENTRICULAR CELL MODELS

HHiromi Kumamoto, Hitomi I Sano, Yasuhiro Naito, Masaru Tomita, HR

Congress of the International Union of Physiological Sciences, Jul 29, 2009
FUNCTIONAL STABILITY OF ARTIFICIAL BIOLOGICAL PACEMAKERS :A SIMULATION STUDY

HMaria Takeuchi, Aoi Miyabe, Yasuhiro Naito, Masaru Tomita, HR

Congress of the International Union of Physiological Sciences, Jul 28, 2009