2013年
Addition and in situ halo-cyclization of omega-alkenyl Grignard reagents with aldehydes, ketones, carbon dioxide, and azodicarboxylate
NEW JOURNAL OF CHEMISTRY
- ,
- ,
- ,
- ,
- 巻
- 37
- 号
- 12
- 開始ページ
- 3873
- 終了ページ
- 3876
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1039/c3nj00765k
- 出版者・発行元
- ROYAL SOC CHEMISTRY
An addition reaction of omega-alkenylmagnesium bromide with aldehydes and consecutive oxidative cyclization with iodobenzene diacetate afforded brominated tetrahydrofuran in one pot. The reaction was also applicable to a one-pot synthesis of 2,5,5-trisubstituted tetrahydrofuran, lactone, and pyrazolidine using a ketone, carbon dioxide, and azodicarboxylate, respectively, as electrophiles. One-pot iodo- and chloro-cyclizations were also possible with alkenylmagnesium iodide and chloride.
- リンク情報
- ID情報
-
- DOI : 10.1039/c3nj00765k
- ISSN : 1144-0546
- eISSN : 1369-9261
- Web of Science ID : WOS:000326984000011