Recently, efficient pairings such as optimal-ate, R-ate, and Xate pairings have been proposed. On the other hand, some pairing-based cryptographic protocols need several pairing calculations for one procedure. Thus, multi-pairing technique will be efficiently applied. This paper optimizes Xate pairing for multi-pairing and then evaluates its efficiency with comparing to the other efficient pairings. Then, it is shown that the multi-pairing with the optimized Xate pairing is the most efficient.