論文

国際誌
2022年8月

Fat signal fraction assessed with MRI predicts hepatic recurrence following hepatic resection for colorectal liver metastases.

Langenbeck's archives of surgery
  • Nozomu Sakai
  • ,
  • Koichi Hayano
  • ,
  • Takashi Mishima
  • ,
  • Katsunori Furukawa
  • ,
  • Tsukasa Takayashiki
  • ,
  • Satoshi Kuboki
  • ,
  • Shigetsugu Takano
  • ,
  • Yohei Kawasaki
  • ,
  • Hisahiro Matsubara
  • ,
  • Masayuki Ohtsuka

407
5
開始ページ
1981
終了ページ
1989
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1007/s00423-022-02482-z

PURPOSE: The effect of hepatic steatosis on the development of colorectal liver metastases (CRLM) remains unknown. This study evaluated the usefulness of fat signal fraction assessed with magnetic resonance imaging (MRI) and the effect of hepatic steatosis on hepatic recurrences following initial hepatectomy for CRLM. METHODS: Between January 2013 and December 2019, 64 patients underwent initial hepatectomy for CRLM. The medical records of these patients were reviewed to evaluate the recurrence and survival outcomes. RESULTS: The fat signal fraction was positively correlated with the nonalcoholic fatty liver disease activity score and liver-spleen ratio. Recurrence following the initial hepatectomy was observed in 48/64 patients, and hepatic recurrence was observed in 30/64 patients. The fat signal fraction was significantly higher in patients with hepatic recurrence after initial hepatectomy. The hepatic recurrence rate was 69.2% in patients with fat signal fraction ≥ 0.0258, which was significantly higher than that in patients with fat signal fraction < 0.0258. Hepatic recurrence-free survival rate was significantly higher in patients with fat signal fraction < 0.0258 than in those with fat signal fraction ≥ 0.0258. Multivariate analyses revealed that fat signal fraction ≥ 0.0258 was an independent risk factor for hepatic recurrence. CONCLUSION: The fat signal fraction assessed with MRI was significantly associated with hepatic recurrence following initial hepatectomy for CRLM.

リンク情報
DOI
https://doi.org/10.1007/s00423-022-02482-z
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/35362752
ID情報
  • DOI : 10.1007/s00423-022-02482-z
  • PubMed ID : 35362752

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