論文

査読有り
2016年

Optical control of neuronal firing via photoinduced electron transfer in donor-acceptor conjugates

CHEMICAL SCIENCE
  • Yuta Takano
  • Tomohiro Numata
  • Kazuto Fujishima
  • Kazuaki Miyake
  • Kazuya Nakao
  • Wesley David Grove
  • Ryuji Inoue
  • Mineko Kengaku
  • Shigeyoshi Sakaki
  • Yasuo Mori
  • Tatsuya Murakami
  • Hiroshi Imahori
  • 全て表示

7
5
開始ページ
3331
終了ページ
3337
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1039/c5sc04135j
出版者・発行元
ROYAL SOC CHEMISTRY

A series of porphyrin-fullerene linked molecules has been synthesized to evaluate the effects of substituents and molecular structures on their charge-separation yield and the lifetime of a final charge-separated state in various hydrophilic environments. The selected high-performance molecule effectively achieved depolarization in a plasma cell membrane by visible light as well as two-photon excitation using a near-infrared light laser. Moreover, it was revealed that the depolarization can trigger neuronal firing in rat hippocampal neurons, demonstrating the potential and versatility for controlling cell functions using light.

リンク情報
DOI
https://doi.org/10.1039/c5sc04135j
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000374859300045&DestApp=WOS_CPL
ID情報
  • DOI : 10.1039/c5sc04135j
  • ISSN : 2041-6520
  • eISSN : 2041-6539
  • Web of Science ID : WOS:000374859300045

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