2016年
Optical control of neuronal firing via photoinduced electron transfer in donor-acceptor conjugates
CHEMICAL SCIENCE
- 巻
- 7
- 号
- 5
- 開始ページ
- 3331
- 終了ページ
- 3337
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1039/c5sc04135j
- 出版者・発行元
- ROYAL SOC CHEMISTRY
A series of porphyrin-fullerene linked molecules has been synthesized to evaluate the effects of substituents and molecular structures on their charge-separation yield and the lifetime of a final charge-separated state in various hydrophilic environments. The selected high-performance molecule effectively achieved depolarization in a plasma cell membrane by visible light as well as two-photon excitation using a near-infrared light laser. Moreover, it was revealed that the depolarization can trigger neuronal firing in rat hippocampal neurons, demonstrating the potential and versatility for controlling cell functions using light.
- リンク情報
- ID情報
-
- DOI : 10.1039/c5sc04135j
- ISSN : 2041-6520
- eISSN : 2041-6539
- Web of Science ID : WOS:000374859300045