Yasuo Mori - My portal

Profile Information

Affiliation: -

J-GLOBAL ID: 201101022156605492
researchmap Member ID: B000003209

External link: http://kaken.nii.ac.jp/ja/r/80212265

Research Interests

Research Areas

Research History

2004 - 2009

教授, 京都大学工学(系)研究科(研究院)
2003 - 2008

教授, 京都大学工学研究科
2007

教授, 京都大学大学院・工学研究科
2005 - 2006

Graduate School of Engineering, Kyoto University
2003 - 2005

教授, 京都大学大学院・工学研究科
2002 - 2003

教授, 岡崎国立共同研究機構
2001 - 2002

教授, 岡崎国立共同研究機構統合バイオサイエンスセンター
1998 - 2001

助教授, 岡崎国立共同研究機構・生理学研究所
2001

教授, 岡崎国立共同研究機構総合バイオサイエンスセンター
1996 - 2000

助教授, 岡崎国立共同研究機構
1996

教授, 岡崎国立共同研究機構
1992 - 1993

Kyoto University

Papers

294

The astrocytic TRPA1 channel mediates an intrinsic protective response to vascular cognitive impairment via LIF production

Masashi Kakae, Hiroki Nakajima, Shota Tobori, Ayaka Kawashita, Jun Miyanohara, Misa Morishima, Kazuki Nagayasu, Takayuki Nakagawa, Eiji Shigetomi, Schuichi Koizumi …

Science Advances, 9(29) eadh0102, Jul, 2023 Peer-reviewed
Inhibition of transient receptor potential cation channel 6 promotes capillary arterialization during post-ischaemic blood flow recovery

T Numaga-Tomita, T Shimauchi, Y Kato, K Nishiyama, A Nishimura, K Sakata, H Inada, S Kita, T Iwamoto, J Nabekura …

BRITISH JOURNAL OF PHARMACOLOGY, 180(1) 94-110, Jan, 2023 Peer-reviewed
Hippocampus-related cognitive disorders develop in the absence of epilepsy and ataxia in the heterozygous Cacna1a mutant mice tottering

Akito Nakao, Katsumi Hayashida, Hiroo Ogura, Yasuo Mori, Keiji Imoto

CHANNELS, 16(1) 113-126, Dec, 2022 Peer-reviewed
Vital but vulnerable: Human TRPV6 is a trade-off of powerful Ca2+ uptake and susceptibility to epithelial barrier dysfunction Comment

Y Mori, M Omori, A Nakao

CELL CALCIUM, 107 102652, Nov, 2022 Peer-reviewed
N-Methylamide-structured SB366791 derivatives with high TRPV1 antagonistic activity: toward PET radiotracers to visualize TRPV1

T Kida, N Takahashi, MX Mori, JCH Sun, H Oota, K Nishino, T Okauchi, Y Ochi, D Kano, U Tateishi …

RSC MEDICINAL CHEMISTRY, 13(10) 1197-1204, Oct, 2022 Peer-reviewed
Myocardial TRPC6-mediated Zn2+ influx induces beneficial positive inotropy through beta-adrenoceptors

S Oda, K Nishiyama, Y Furumoto, Y Yamaguchi, A Nishimura, XK Tang, Y Kato, T Numaga-Tomita, T Kaneko, S Mangmool …

NATURE COMMUNICATIONS, 13(1) 6374, Oct, 2022 Peer-reviewed
Functional coupling of TRPM2 and extrasynaptic NMDARs exacerbates excitotoxicity in ischemic brain injury

Pengyu Zong, Jianlin Feng, Zhichao Yue, Yunfeng Li, Gongxiong Wu, Baonan Sun, Yanlin He, Barbara Miller, Albert S. Yu, Zhongping Su …

NEURON, 110(12) 1944-+, Jun, 2022 Peer-reviewed
Critical contributions of pre-S1 shoulder and distal TRP box in DAG-activated TRPC6 channel by PIP2 regulation

Masayuki X. Mori, Ryo Okada, Reiko Sakaguchi, Hideharu Hase, Yuko Imai, Onur K. Polat, Satoru G. Itoh, Hisashi Okumura, Yasuo Mori, Yasushi Okamura …

SCIENTIFIC REPORTS, 12(1) ARTN 10766, Jun, 2022 Peer-reviewed
A two-step screening to optimize the signal response of an auto-fluorescent protein-based biosensor

Shunsuke Tajima, Eiji Nakata, Reiko Sakaguchi, Masayuki Saimura, Yasuo Mori, Takashi Morii

RSC ADVANCES, 12(24) 15407-15419, May, 2022 Peer-reviewed
Cell-autonomous control of intracellular temperature by unsaturation of phospholipid acyl chains

Akira Murakami, Kohjiro Nagao, Reiko Sakaguchi, Keisuke Kida, Yuji Hara, Yasuo Mori, Kohki Okabe, Yoshie Harada, Masato Umeda

CELL REPORTS, 38(11) ARTN 110487-110487, Mar, 2022 Peer-reviewed
The mechanosensitive ion channel PIEZO1 promotes satellite cell function in muscle regeneration

K Hirano, M Tsuchiya, A Shiomi, S Takabayashi, M Suzuki, Y Ishikawa, Y Kawano, Y Takabayashi, K Nishikawa, K Nagao …

LIFE SCIENCE ALLIANCE, 6(2) e202201783-e202201783, Feb, 2022 Peer-reviewed
Functionally deficient TRPV6 variants contribute to hereditary and familial chronic pancreatitis

Shin Hamada, Emmanuelle Masson, Jian-Min Chen, Reiko Sakaguchi, Vinciane Rebours, Louis Buscail, Ryotaro Matsumoto, Yu Tanaka, Kazuhiro Kikuta, Fumiya Kataoka …

HUMAN MUTATION, 43(2) 228-239, Feb, 2022 Peer-reviewed
C-type natriuretic peptide facilitates autonomic Ca²⁺ entry in growth plate chondrocytes for stimulating bone growth

Yuu Miyazaki, Atsuhiko Ichimura, Ryo Kitayama, Naoki Okamoto, Tomoki Yasue, Feng Liu, Takaaki Kawabe, Hiroki Nagatomo, Yohei Ueda, Ichiro Yamauchi …

eLife, 11 ARTN e71931, 2022 Peer-reviewed
Osteoclasts adapt to physioxia perturbation through DNA demethylation

Keizo Nishikawa, Shigeto Seno, Toshitada Yoshihara, Ayako Narazaki, Yuki Sugiura, Reito Shimizu, Junichi Kikuta, Reiko Sakaguchi, Norio Suzuki, Norihiko Takeda …

EMBO REPORTS, 22(12) ARTN e53035, Dec, 2021 Peer-reviewed
温覚と圧・触覚の受容体の発見 : 分子生理学の始まりの終わり

森泰生, 原雄二

化学 = Chemistry, 76(12) 28-31, Dec, 2021
Activation of Astrocytes in the Persistence of Post-hypoxic Respiratory Augmentation

Isato Fukushi, Kotaro Takeda, Mieczyslaw Pokorski, Yosuke Kono, Masashi Yoshizawa, Yohei Hasebe, Akito Nakao, Yasuo Mori, Hiroshi Onimaru, Yasumasa Okada

FRONTIERS IN PHYSIOLOGY, 12 ARTN 757731-757731, Oct, 2021 Peer-reviewed
Deep-Red/Near-Infrared Turn-On Fluorescence Probes for Aldehyde Dehydrogenase 1A1 in Cancer Stem Cells

Masahiro Oe, Koji Miki, Yoshifumi Ueda, Yasuo Mori, Aoi Okamoto, Yohei Funakoshi, Hironobu Minami, Kouichi Ohe

ACS SENSORS, 6(9) 3320-3329, Sep, 2021 Peer-reviewed
MrgprB4 in trigeminal neurons expressing TRPA1 modulates unpleasant sensations

Shota Tobori, Haruka Hiyama, Takahito Miyake, Yuichi Yano, Kazuki Nagayasu, Hisashi Shirakawa, Takayuki Nakagawa, Yasuo Mori, Shuji Kaneko

JOURNAL OF PHARMACOLOGICAL SCIENCES, 146(4) 200-205, Aug, 2021 Peer-reviewed
Extreme deformability of insect cell membranes is governed by phospholipid scrambling

Akifumi Shiomi, Kohjiro Nagao, Nobuhiro Yokota, Masaki Tsuchiya, Utako Kato, Naoto Juni, Yuji Hara, Masayuki X. Mori, Yasuo Mori, Kumiko Ui-Tei …

Cell Reports, 35(10) ARTN 109219, Jun, 2021 Peer-reviewed
V for versatility: TRPV4 Ca2+ entry channel plays multiple roles in invadosome regulation

Yasuo Mori

CELL CALCIUM, 96 ARTN 102387, Jun, 2021 Peer-reviewed

Misc.

Redox signal-mediated sensitization of transient receptor potential melastatin 2 (TRPM2) to temperature affects macrophage functions

Makiko Kashio, Takaaki Sokabe, Kenji Shintaku, Takayuki Uematsu, Naomi Fukuta, Noritada Kobayashi, Yasuo Mori, Makoto Tominaga

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 109(17) 6745-6750, Apr, 2012 Peer-reviewed
"TRPA1 チャネルの酸素感受機構の解明”

沼田朋大, 高橋重成, 清中茂樹, 香西大輔, 森泰生

第89 回日本生理学会大会, 2012.3.29, 2012 Peer-reviewed
“血中酸素飽和度を感知するTRPAl ”

高橋重成, 清中茂樹, 沼田朋大, 香西大輔, 森泰生

第85回日本薬理学会, 2012.3.14, 2012 Peer-reviewed
Development of the immobilization technology of functional proteins on DNA origami

E. Nakata, C. Uwatoko, F.F. Liew, S. Kiyonaka, Y. Mori, Y. Katsuta, M. Endo, H. Sugiyama, T. Morii

The 38th International Symposium on Nucleic Acid Chemistry，Hokkaido，2011.11.9-11, 2011 Peer-reviewed
“TRP チャネルによる酸素感受性”

高橋重成, 森泰生

第84回日本生化学会大会，2011.9.11, 2011 Peer-reviewed
DNA origami上への機能性タンパク質固定化技術の開発

中田栄司, 上床知佐奈, 劉芳芳, 清中茂樹, 森泰生, 勝田陽介, 遠藤政幸, 杉山弘, 森井孝

第5回バイオ関連化学シンポジウム，つくば国際会議場「エポカルつくば」，2011.9.12-14, 2011 Peer-reviewed
TRPM1 is a component of the retinal ON bipolar cell transduction channel in the mGluR6 cascade

Chieko Koike, Takehisa Obara, Yoshitsugu Uriu, Tomohiro Numata, Rikako Sanuki, Kentarou Miyata, Toshiyuki Koyasu, Shinji Ueno, Kazuo Funabiki, Akiko Tani …

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 107(1) 332-337, Jan, 2010 Peer-reviewed
STIM protein coupling in the activation of Orai channels

Youjun Wang, Xiaoxiang Deng, Yandong Zhou, Eunan Hendron, Salvatore Mancarella, Michael F. Ritchie, Xiang D. Tang, Yoshihiro Baba, Tomohiro Kurosaki, Yasuo Mori …

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 106(18) 7391-7396, May, 2009 Peer-reviewed
Selective and direct inhibition of TRPC3 channels underlies biological activities of a pyrazole compound

Shigeki Kiyonaka, Kenta Kato, Motohiro Nishida, Kazuhiro Mio, Takuro Numaga, Yuichi Sawaguchi, Takashi Yoshida, Minoru Wakamori, Emiko Mori, Tomohiro Numata …

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 106(13) 5400-5405, Mar, 2009 Peer-reviewed
TRPM2チャネルによる活性酸素シグナル増幅と慢性炎症の関連

山本伸一郎, 清水俊一, 森泰生

日本薬理学雑誌, 134(3) 122-126, 2009
Physiological roles of presynaptic Ca^<2+> channel complexes on neurotransmitter release

KIYONAKA Shigeki, URIU Yoshitsugu, MIKI Takafumi, MORI Yasuo

80(7) 658-661, Jul 25, 2008
The functional analysis of TRPM1 in mammalian retinal bipolar cells

Chieko Koike, Takehisa Obara, Yukitsugu Uriu, Kentaro Miyata, Toshiyuki Koyasu, Akiko Tani, Mineo Kondo, Yasuo Mori, Masao Tachibana, Takahisa Furukawa

NEUROSCIENCE RESEARCH, 61 S59-S59, 2008 Peer-reviewed
蛍光性バイオセンサーによるイノシトール四リン酸細胞内動態の計測

坂口怜子, 清中茂樹, 森泰生, 森井孝

日本化学会第88春季年会，立教大学池袋キャンパスおよび立教池袋中学校・高等学校，2008.3.26-30, 2008 Peer-reviewed
TRPM7 channels in hippocampal neurons detect levels of extracellular divalent cations

Wen-Li Wei, Hong-Shuo Sun, Michelle E. Olah, Xiujun Sun, Elzbieta Czerwinska, Waldemar Czerwinski, Yasuo Mori, Beverley A. Orser, Zhi-Gang Xiong, Michael F. Jackson …

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 104(41) 16323-16328, Oct, 2007 Peer-reviewed
アンジオテンシンIIで誘発される心肥大の分子機構 : TRPタンパク質を巡って

西田基宏, 小野原直哉, 井上隆司, 森泰生, 黒瀬等

日本臨床生理学会雑誌 = Japanese journal of applied physiology, 37(4) 171-175, Aug 1, 2007
Construction of Fluorescent Sensors to Quantitatively Assess Inositol Tetrakisphosphate (IP4) in Single Cell

R Sakaguchi, K Sugimoto, S Kiyonaka, Y Mori, T Morii

The 2nd International workshop on Approaches to single-cell Analysis, 早稲田大学，井深大記念館，2007.9.6-7, 2007 Peer-reviewed
細胞内情報伝達経路の可視化を目指した蛍光分子センサーの開発

坂口怜子, 杉本健二, 清中茂樹, 森泰生, 森井孝

第22回生体機能関連化学シンポジウム，東北大学，多元物質科学研究所，2007.9.28-29, 2007 Peer-reviewed
Coupling of STIM1 to store-operated Ca2+ entry through its constitutive and inducible movement in the endoplasmic reticulum

Yoshihiro Baba, Kenji Hayashit, Yoko Fujii, Akiko Mizushima, Hiroshi Watarai, Minoru Wakamori, Takuro Numaga, Yasuo Mori, Masamitsu Iino, Masaki Hikida …

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 103(45) 16704-16709, Nov, 2006 Peer-reviewed
A functional AMPA receptor-calcium channel complex in the postsynaptic membrane

MG Kang, CC Chen, M Wakamori, Y Hara, Y Mori, KP Campbell

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 103(14) 5561-5566, Apr, 2006 Peer-reviewed
Cyclosporin and Timothy syndrome increase mode 2 gating of CaV1.2 calcium channels through aberrant phosphorylation of S6 helices

C Erxleben, YH Liao, S Gentile, D Chin, C Gomez-Alegria, Y Mori, L Birnbaumer, DL Armstrong

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 103(10) 3932-3937, Mar, 2006 Peer-reviewed

Books and Other Publications

Chapter21 Receptor Signaling Integration by TRP Channelsomes

Yasuo Mori, Taketoshi Kajimoto, Akito Nakao, Nobuaki Takahashi, Shigeki Kiyonaka (Role: Contributor)

Springer Science 十Business Media B.V., 2011

Professional Memberships

Research Projects

ミトコンドリア活性に伴う細胞内温度変化の計測とその生理学的意義に関する研究

科学研究費補助金(挑戦的萌芽研究), 日本学術振興会, 2008 - 2009

森泰生
レドックス感受性TRPチャネル群の炎症性細胞遊走における意義の分子医学的解明

科学研究費補助金(基盤研究(A)), 日本学術振興会, 2008 - 2009

森泰生
Ca2+チャネル分子複合体の生体膜集積機構とその生理的意義

科学研究費補助金(特定領域研究), 文部科学省, 2005 - 2009

森泰生
TRPCa2+チャネル群によるシグナル制御とその意義に関する分子医学的研究

科学研究費補助金(基盤研究(B)), 日本学術振興会, 2006 - 2007

森泰生