Yoko Chiba

Profile Information

Affiliation: Senior Scientist, RIKEN Center for Sustainable Resource Science, RIKEN
: Associate professor, University of Tsukuba

Degree: 博士（農学）(東京大学)

Researcher number: 70638981
J-GLOBAL ID: 201401070427719088
researchmap Member ID: B000242958

External link: https://kaken.nii.ac.jp/d/r/70638981.ja.html

RIKEN HP

http://rnakamura-lab.riken.jp/index.html

Research Interests

Research Areas

Life sciences / Applied biochemistry /

Research History

Oct, 2021 - Present

Associate professor, Faculty of Life and Environmental Sciences, University of Tsukuba
Jun, 2021 - Present

Senior Scientist, RIKEN Center for Sustainable Resource Science, RIKEN
Oct, 2022 - Oct, 2022

Guest scientist, Terrestrial microbiology, Max Planck Institute
Apr, 2019 - May, 2021

Research Scientist, Center for Sustainable Resource Science (CSRS), RIKEN
Apr, 2016 - Mar, 2019

ポストドクトラル研究員, 深海・地殻内生物圏研究分野, 海洋研究開発機構
May, 2012 - Mar, 2016

Graduate School of Life and Environmental Sciences, University of Tsukuba
Apr, 2012 - Apr, 2012

JSPS Research Fellowship for Young Scientists (PD), Graduate School of Agricultural and Life Sciences Biotechnology, The University of Tokyo
Apr, 2011 - Mar, 2012

JSPS Research Fellowship for Young Scientists (doctoral cource), Graduate School of Agricultural and Life Sciences Biotechnology, The University of Tokyo
Apr, 2009 - Mar, 2012

PhD student, Graduate School of Agricultural and Life Sciences Biotechnology, The University of Tokyo
Apr, 2007 - Mar, 2009

master course student, Graduate School of Agriculture, Kyoto University
Apr, 2005 - Mar, 2009

Faculty of Agriculture Faculty of Agriculture, Kyoto University

Awards

Apr, 2024

CSRS Incentive Award, Thermodynamic principle to enhance enzymatic activity using the substrate affinity, RIKEN Center for Sustainable Resource Science

Hideshi Ooka, Yoko Chiba
Mar, 2020

JSBBA Award for Young Women Scientists, Japan Society for Bioscience, Biotechnology, and Agrochemistry
Mar, 2017

Award for Excellence to Authors Publishing in Bioscience, Biotechnology, and Biochemistry in 2016, Discovery of an intermolecular disulfide bond required for the thermostability of a heterodimeric protein from the thermophile Hydrogenobacter thermophilus, The Japan Society for Bioscience, Biotechnology, and Agrochemistry

Keug Tae Kim, Yoko Chiba, Hiroyuki Arai, Masaharu Ishii
Oct, 2016

Fermentation and Metabolism Research Award, Discovery of novel enzymes: Diversity and evolutionary history of proteins involved in central metabolism, Japan Bioindustry Association

Yoko Chiba
Aug, 2016

Poster Prize, Molecular basis on microbial one-carbon metabolism, Gordon Research Conference

Yoko Chiba
Mar, 2015

Topics award、 The 2015 Annual Conference, Japan Society for Bioscience, Biotechnology and Agrochemistry

Yoko Chiba
Mar, 2015

The best presentation award for young scientist The 84th annual meeting of the Japanese society of parasitology, Japanese society of parasitology

Yoko Chiba

Major Papers

Thermodynamic principle to enhance enzymatic activity using the substrate affinity.

Hideshi Ooka, Yoko Chiba, Ryuhei Nakamura

Nature communications, 14(1) 4860-4860, Aug 24, 2023 Peer-reviewed
Fragmentation of acetate-CoA ligase gives a clue to understand domain rearrangement history of NDP-forming acyl-CoA synthetase superfamily proteins.

Yoko Chiba, Mariko Shitara, Ken Takai

Bioscience, biotechnology, and biochemistry, 1-9, Jun 14, 2020 Peer-reviewed
Structural comparisons of phosphoenolpyruvate carboxykinases reveal the evolutionary trajectories of these phosphodiester energy conversion enzymes.

Yoko Chiba, Takuya Miyakawa, Yasuhiro Shimane, Ken Takai, Masaru Tanokura, Tomoyoshi Nozaki

The Journal of biological chemistry, 294(50) 19269-19278, Dec 13, 2019 Peer-reviewed
Discovery and analysis of a novel type of the serine biosynthetic enzyme phosphoserine phosphatase in Thermus thermophilus.

Yoko Chiba, Ayako Yoshida, Shigeru Shimamura, Masafumi Kameya, Takeo Tomita, Makoto Nishiyama, Ken Takai

The FEBS journal, 286(4) 726-736, Feb, 2019 Peer-reviewed
Phosphoserine Phosphatase Is Required for Serine and One-Carbon Unit Synthesis in Hydrogenobacter thermophilus

Keugtae Kim, Yoko Chiba, Azusa Kobayashi, Hiroyuki Arai, Masaharu Ishii

JOURNAL OF BACTERIOLOGY, 199(21), Nov, 2017 Peer-reviewed
Heterogeneity of the serine synthetic pathway in Entamoeba species

Yoko Chiba, Takashi Makiuchi, Ghulam Jeelani, Tomoyoshi Nozaki

MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 207(2) 56-60, Jun, 2016 Peer-reviewed
Discovery of an intermolecular disulfide bond required for the thermostability of a heterodimeric protein from the thermophile Hydrogenobacter thermophilus

Keug Tae Kim, Yoko Chiba, Hiroyuki Arai, Masaharu Ishii

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 80(2) 232-240, Feb, 2016 Peer-reviewed
Discovery of PPi-type Phosphoenolpyruvate Carboxykinase Genes in Eukaryotes and Bacteria

Yoko Chiba, Ryoma Kamikawa, Kumiko Nakada-Tsukui, Yumiko Saito-Nakano, Tomoyoshi Nozaki

JOURNAL OF BIOLOGICAL CHEMISTRY, 290(39) 23960-23970, Sep, 2015 Peer-reviewed
Structural Units Important for Activity of a Novel-type Phosphoserine Phosphatase from Hydrogenobacter thermophilus TK-6 Revealed by Crystal Structure Analysis

Yoko Chiba, Shoichiro Horita, Jun Ohtsuka, Hiroyuki Arai, Koji Nagata, Yasuo Igarashi, Masaru Tanokura, Masaharu Ishii

JOURNAL OF BIOLOGICAL CHEMISTRY, 288(16) 11448-11458, Apr, 2013 Peer-reviewed
Crystallization and preliminary X-ray diffraction analysis of a novel type of phosphoserine phosphatase from Hydrogenobacter thermophilus TK-6

Yoko Chiba, Shoichiro Horita, Jun Ohtsuka, Hiroyuki Arai, Koji Nagata, Yasuo Igarashi, Masaru Tanokura, Masaharu Ishii

ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS, 68(Pt 8) 911-913, Aug, 2012 Peer-reviewed
Discovery and Analysis of Cofactor-dependent Phosphoglycerate Mutase Homologs as Novel Phosphoserine Phosphatases in Hydrogenobacter thermophilus

Yoko Chiba, Kenro Oshima, Hiroyuki Arai, Masaharu Ishii, Yasuo Igarashi

JOURNAL OF BIOLOGICAL CHEMISTRY, 287(15) 11934-11941, Apr, 2012 Peer-reviewed
Mechanism for folate-independent aldolase reaction catalyzed by serine hydroxymethyltransferase

Yoko Chiba, Tohru Terada, Masafumi Kameya, Kentaro Shimizu, Hiroyuki Arai, Masaharu Ishii, Yasuo Igarashi

FEBS JOURNAL, 279(3) 504-514, Feb, 2012 Peer-reviewed
Isolation of a Bacterium Possessing a Haloacid Dehalogenase from a Marine Sediment Core

Yoko Chiba, Takashi Yoshida, Norihiro Ito, Hiroshi Nishimura, Chiaki Imada, Hisato Yasuda, Yoshihiko Sako

MICROBES AND ENVIRONMENTS, 24(3) 276-279, 2009 Peer-reviewed

Misc.

セリン生合成酵素と酵素の動力学パラメータの多様性に関する発見と考察

千葉洋子

酵素工学ニュース, (86) 8-12, Oct, 2021 InvitedLead authorCorresponding author
アミノ酸生合成とCO2固定経路の密接な関係グリーンバイオケミストリーから生命進化まで

千葉洋子

化学と生物, 59(9) 458-463, Sep, 2021 InvitedLead authorCorresponding author
バイオ系のキャリアデザイン効率的ではないかもしれないが満足度は高いこれまで

千葉洋子

生物工学会誌, 95(9) 557-559, 2017 Lead authorCorresponding author
Identification and characterization of novel PEP carboxykinase from Entamoeba histolytica

Chiba Yoko, Kamikawa Ryoma, Tsukui Kumiko, Nakano Yumiko, Nozaki Tomoyoshi

Mar, 2015
Identification and characterization of a lost central metabolic enzyme, phosphoenolpyruvate carboxykinase

Chiba Yoko, Kamikawa Ryoma, Nozaki Tomoyoshi

Mar, 2015
大学院生出張授業プロジェクト

千葉洋子

生物工学会誌 : seibutsu-kogaku kaishi, 88(6) 306-307, Jun 25, 2010
P-151 海洋コアからのハロ酸脱ハロゲン酵素保有細菌の分離(ポスター発表)

千葉洋子, 吉田天士, 伊藤典弘, 西村宏, 今田千秋, 安田尚登, 左子芳彦

日本微生物生態学会講演要旨集, 25th(25), Nov 21, 2009

Books and Other Publications

独立栄養微生物によるCO2資源化技術

新井博之,亀谷将史,石井正治(監修) (Role: Contributor, 第4章合成生物学による新規独立栄養生物・炭酸固定経路の創出)

シーエムシー出版, Dec, 2023 (ISBN: 9784781317564)

Presentations

Exploring a novel glycine biosynthesis pathway in Thermodesulfatator indicus, a thermophilic sulfate-reducing bacterium using isotopomer analysis.

Tomoyuki Wakashima, Yuto Fukuyama, Shigeru Shimamura, Nao Tsunematsu, Takuro Nunoura, Yoko Chiba

The 36th JSME & The 13th ASME, Nov 29, 2023
Directionality of CO2 fixation pathways in the presence of other carbon sources

Yoko Chiba

The 36th JSME & The 13th ASME, Nov 28, 2023 Invited
Mathematical Theory to Maximize Enzymatic Activity Under Thermodynamic Constraints

Hideshi Ooka, Yoko Chiba, Ryuhei Nakamura

10th International Congress on Industrial and Applied Mathematics, Aug 20, 2023
酵素動⼒学パラメータの最適値について

千葉洋子

⽇本農芸化学会関⻄⽀部第526回講演会, Jul 8, 2023 Invited
Analysis of a homogeneous enzyme kinetics using the Sabatier principle, a concept of artificial catalysis

Mar 15, 2023
酵素活性を最大化する結合性相互作用の予測

大岡英史, 千葉洋子, 中村龍平

電気化学会第90回大会, Mar, 2023
The rediscovery of obligately chemolithoautotrophs as chemolithomixotrophs provides insights into the ancestral carbon fixation metabolism

Yoko Chiba, Tomomi Sumida, Masafumi Kameya, Yoshito Chikaraishi, Takuro Nunoura

Gordon Research Conference: Molecular Basis of Microbial One-Carbon Metabolism, Aug 8, 2022
酵素ミカエリスメンテン定数（Km値）による代謝制御

千葉洋子, 大岡英史, Marie Wintzer, 常松奈緒, 中村龍平

日本農芸化学会2022年度大会, Mar 16, 2022
Visualization of CO2 Fixation Pathways in Thermophilic Bacteria

Yoko Chiba, Tomomi Sumida, Masafumi Kameya, Yoshito Chikaraishi, Takuro Nunoura

RIKEN BDR Symposium 2022 Emergence in Biological Systems: Challenges to Bridging Hierarchies, Mar 2, 2022
Did early life use pyrophosphate as an energy source? A structural biological approach to the mysteries of life evolution

Yoko Chiba, Takuya Miyakawa, Masaru Tanokura

Dec 1, 2021 Invited
Characterization of a Non-Classic Type Phosphoserine Phosphatase Homolog in Thermodesulfidibacter takaii, a Thermophilic, Autotrophic Bacterium in the Phylum Aquificae

Wintzer Marie, Chiba Yoko, Nakamura Ryuhei

Experimental Biology 2021, Apr 28, 2021

Major Research Projects

アーキアの新規セリン生合成経路同定を通じた中央代謝進化の解明

科学研究費助成事業基盤研究(B), 基盤研究(B), 日本学術振興会, Apr, 2023 - Mar, 2027

千葉洋子
微生物におけるCO同化経路の特定

科学研究費助成事業学術変革領域研究(A), 学術変革領域研究(A), 日本学術振興会, Apr, 2023 - Mar, 2025

千葉洋子
酵素のKm値再考察：最適値を決める因子の探索

ACT-X, 科学技術振興機構, Dec, 2020 - Mar, 2023

千葉洋子
Understanding carbonate fixation metabolisms by revealing novel amino acid biosynthetic pathways in autotrophic bacteria

Grants-in-Aid for Scientific Research Grant-in-Aid for Early-Career Scientists, Grant-in-Aid for Early-Career Scientists, Japan Society for the Promotion of Science, Apr, 2019 - Mar, 2022

Chiba Yoko
原始生命におけるエネルギー通貨産生システムの再現

科学研究費助成事業新学術領域研究(研究領域提案型), 新学術領域研究(研究領域提案型), 日本学術振興会, Apr, 2017 - Mar, 2019

千葉洋子
Relationship between anaerobic metabolisms and organelle evolution of Entamoeba histolytica

Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B), Grant-in-Aid for Young Scientists (B), Japan Society for the Promotion of Science, Apr, 2014 - Mar, 2017

CHIBA Yoko
代謝生化学とオミックスの融合による絶対独立栄養性水素細菌のグリシン代謝系の解明

科学研究費助成事業特別研究員奨励費, 特別研究員奨励費, 日本学術振興会, 2011 - 2012

千葉洋子

Profile Information

Research Interests

Research Areas

Research History

Awards

Major Papers

Misc.

Books and Other Publications

Presentations

Major Research Projects

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Coauthors