2017年4月
Determination of O:4 antigen-antibody affinity level in O: 5 antigen positive and negative variants of Salmonella enterica serovar Typhimurium
FEMS MICROBIOLOGY LETTERS
- 巻
- 364
- 号
- 7
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1093/femsle/fnx062
- 出版者・発行元
- OXFORD UNIV PRESS
Salmonella enterica serovar Typhimurium (S. Typhimurium) has two serological variants: one that expresses the O:5 antigen (1,4,5,12: i:1,2) and one that lacks O:5 antigen (1,4,12:i:1,2). For serotyping, S. Typhimurium is agglutinated by diagnostic O:4 antigen serum. This study was carried out to compare the antigen-antibody affinity of O:4 antigen in S. Typhimurium chi 3306 O:5-positive and S. Typhimurium chi 3306 O:5-negative strains. The affinity of O:4 antigen with O:4 antigen serum was found to be stronger in the O:5-negative strains compared to O:5-positive strains. Next, we investigated the antigen-antibody affinity of O:4 antigen with O:4 antigen serum in field strains of S. Typhimurium, which showed the same tendency in affinity as seen with S. Typhimurium chi 3306 O:5-positive and negative strains. This study suggests that the presence or absence of O:5 antigen causes differences in O:4 agglutination reactions with different field strains of S. Typhimurium.
- リンク情報
- ID情報
-
- DOI : 10.1093/femsle/fnx062
- ISSN : 0378-1097
- eISSN : 1574-6968
- PubMed ID : 28369258
- Web of Science ID : WOS:000404487100002