論文

査読有り
2007年11月

Analysis of the p450 aromatase gene expression in the Xenopus brain and gonad

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
  • Junshin Iwabuchi
  • ,
  • Syun Wako
  • ,
  • Tatsuya Tanaka
  • ,
  • Azusa Ishikawa
  • ,
  • Yuki Yoshida
  • ,
  • Shohei Miyata

107
3-5
開始ページ
149
終了ページ
155
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1016/j.jsbmb.2007.01.007
出版者・発行元
PERGAMON-ELSEVIER SCIENCE LTD

Analysis of 5'-RACE clones revealed two Cyp19 transcript variants (gonad p450 aroms 1 and 2) in the gonads and one Cyp transcript (brain p450 arom) in the brain that differed in their 5'-untranslated region (UTR). Since all cDNAs contained an identical open reading frame, it is considered that while Xenopus aromatase may be encoded by a single Cyp19 gene, it is transcribed by tissue-specific promoters, each of which may be regulated by a distinct set of transcriptional factors. While gonad p450 aroms I and 2 and brain p450 arom were expressed in the gonads, brain p450 arom was the predominantly expressed aromatase gene in the brain, with a low expression level of gonad p450 arom 1. (C) 2007 Elsevier Ltd. All rights reserved.

Web of Science ® 被引用回数 : 25

リンク情報
DOI
https://doi.org/10.1016/j.jsbmb.2007.01.007
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/17669643
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000250183600003&DestApp=WOS_CPL

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