小山芳伸 (YOSHINOBU KOYAMA) - マイポータル

基本情報

所属: 岡山赤十字病院自己免疫疾患センター　膠原病リウマチ内科センター長、部長 (岡山大学医学部臨床教授)

研究者番号: 10716822
ORCID iD: https://orcid.org/0000-0003-0180-699X
J-GLOBAL ID: 202501013233057174
researchmap会員ID: R000080170

論文

Phase 3 Trial of Secukinumab in Polymyalgia Rheumatica.

John H Stone, Frank Buttgereit, Alain Saraux, Wolfgang A Schmidt, Christian Dejaco, Robert Spiera, Bhaskar Dasgupta, Edit Drescher, Andrew Jordan, Libor Novosad …

The New England journal of medicine 2026年6月3日
A pilot transcriptomic study of a novel multitargeted BRT regimen for anti-MDA5 antibody-positive dermatomyositis: improving survival over conventional therapy.

Moe Tokunaga, Yu Nakai, Yoshiharu Sato, Mitori Hiratsuka, Yoshinori Matsumoto, Takeshi Nakatsue, Takako Saeki, Takatsune Umayahara, Jun Wada, Yoshinobu Koyama

Frontiers in immunology 16 1568338-1568338 2025年
Bone marrow edema detection for diagnostic support of axial spondyloarthritis using MRI.

Akira Kojima, Tetsuya Tomita, Shigeyoshi Tsuji, Yuho Kadono, Kurisu Tada, Taiki Nozaki, Masashi Tamaki, Yoshinobu Koyama, Hiroaki Dobashi, Tadashi Okano …

International journal of computer assisted radiology and surgery 19(9) 1699-1711 2024年9月
Treatment resistance of rheumatoid arthritis relates to infection of periodontal pathogenic bacteria: a case-control cross-sectional study.

Kazu Takeuchi-Hatanaka, Yoshinobu Koyama, Kentaro Okamoto, Kyosuke Sakaida, Tadashi Yamamoto, Shogo Takashiba

Scientific reports 12(1) 12353-12353 2022年7月19日
Risk stratification and clinical course of hepatitis B virus reactivation in rheumatoid arthritis patients with resolved infection: final report of a multicenter prospective observational study at Japanese Red Cross Hospital.

Wataru Fukuda, Tadamasa Hanyu, Masaki Katayama, Shinichi Mizuki, Akitomo Okada, Masayuki Miyata, Yuichi Handa, Masatoshi Hayashi, Yoshinobu Koyama, Kaoru Arii …

Arthritis research & therapy 21(1) 255-255 2019年11月28日
Clinical manifestations of skin, lung and muscle diseases in dermatomyositis positive for anti-aminoacyl tRNA synthetase antibodies.

Hiroko Fukamatsu, Yoji Hirai, Tomoko Miyake, Tatsuya Kaji, Shin Morizane, Emi Yokoyama, Toshihisa Hamada, Takashi Oono, Yoshinobu Koyama, Seiichiro Norikane …

The Journal of dermatology 46(10) 886-897 2019年10月
A novel scoring system based on common laboratory tests predicts the efficacy of TNF-inhibitor and IL-6 targeted therapy in patients with rheumatoid arthritis: a retrospective, multicenter observational study

Jin Nakagawa, Yoshinobu Koyama, Atsushi Kawakami, Yukitaka Ueki, Hiroshi Tsukamoto, Takahiko Horiuchi, Shuji Nagano, Ayumi Uchino, Toshiyuki Ota, Mitsuteru Akahoshi …

Arthritis Research & Therapy 19(1) 185-185 2017年12月
Incidence of hepatitis B virus reactivation in patients with resolved infection on immunosuppressive therapy for rheumatic disease: a multicentre, prospective, observational study in Japan.

Wataru Fukuda, Tadamasa Hanyu, Masaki Katayama, Shinichi Mizuki, Akitomo Okada, Masayuki Miyata, Yuichi Handa, Masatoshi Hayashi, Yoshinobu Koyama, Kaoru Arii …

Annals of the rheumatic diseases 76(6) 1051-1056 2017年6月
Systemic IgG4-related disease with extensive peripheral nerve involvement that progressed from localized IgG4-related lymphadenopathy: an autopsy case.

Masayoshi Fujii, Yasuharu Sato, Nobuya Ohara, Kenji Hashimoto, Haruhiko Kobashi, Yoshinobu Koyama, Tadashi Yoshino

Diagnostic pathology 9 41-41 2014年2月21日
A concomitant case of giant cell arteritis and microscopic polyangiitis with hemoperitoneum by rupture of the gastroepiploic artery.

Kenji Fujii, Tomomi Tsutsumi, Kensuke Takaoka, Yasuhiro Osugi, Satoshi Ando, Yoshinobu Koyama

Modern rheumatology 22(6) 934-8 2012年11月
A case of adult-onset Still's disease complicated by hemophagocytic syndrome and interstitial pneumonia with pneumomediastinum/recurrent pneumothorax.

Kenji Fujii, Yuichi Kitamura, Yasuhiro Osugi, Yoshinobu Koyama, Toshiyuki Ota

International journal of rheumatic diseases 15(4) e60-2 2012年8月
Etanercept in combination with conventional disease-modifying antirheumatic drugs (DMARDs) in the treatment of rheumatoid arthritis patients intolerant to methotrexate.

Yoshinobu Koyama, Hirokazu Shiraishi, Toshiyuki Ohta, Ayumi Uchino

Modern rheumatology 22(1) 100-8 2012年2月
Adult-onset Still's disease complicated by autoimmune hepatitis: successful treatment with infliximab.

Kenji Fujii, Ryo Rokutanda, Yasuhiro Osugi, Yoshinobu Koyama, Toshiyuki Ota

Internal medicine (Tokyo, Japan) 51(9) 1125-8 2012年
Interleukin 1 activates STAT3/nuclear factor-kappaB cross-talk via a unique TRAF6- and p65-dependent mechanism.

Yasuhiro Yoshida, Arvind Kumar, Yoshinobu Koyama, Haibing Peng, Ahmet Arman, Jason A Boch, Philip E Auron

The Journal of biological chemistry 279(3) 1768-76 2004年1月16日
Characterization of a cascade of protein interactions initiated at the IL-1 receptor.

Jason A Boch, Yasuhiro Yoshida, Yoshinobu Koyama, Nawarat Wara-Aswapati, Hiabing Peng, Sebnem Unlu, Philip E Auron

Biochemical and biophysical research communications 303(2) 525-31 2003年4月4日

共同研究・競争的資金等の研究課題

予後不良因子を複数有する抗MDA5抗体陽性皮膚筋炎を対象とした､新規BRT療法（高用量ステロイド+Baricitinib+Rituximab+ Tacrolimus）の有効性及び安全性をTC療法（Tacrolimus+ Cyclophosphamide）と比較する多施設共同試験

国立研究開発法人日本医療研究開発機構難治性疾患実用化研究事業 2025年4月 - 2028年3月
関節リウマチおよび結合織疾患患者のB型肝炎ウイルス再活性化に関する観察研究

国立研究開発法人日本医療研究開発機構免疫アレルギー疾患実用化研究事業 2015年4月 - 2018年3月

小山芳伸

基本情報

論文

共同研究・競争的資金等の研究課題

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