Matsumoto Yoshitaka

J-GLOBAL         Last updated: Jun 28, 2019 at 09:45
Matsumoto Yoshitaka
Doctor of Medical Science(Chiba University), Master of Health and Medicine(Ibaraki Prefectural University of Health Sciences)
Research funding number

Academic & Professional Experience

Assistant Professor, University of Tsukuba Faculty of Medicine
Apr 2004
Mar 2006
Radiological technologist, Hospital of Research Center for Charged Particle Therapy, 放射線医学総合研究所
Apr 2006
Mar 2007
Assistant, Research Center for Charged Particle Therapy, National Institute of Radiological Sciences
Apr 2007
Mar 2008
Junior Researcher Associate, Research Center for Charged Particle Therapy, National Institute of Radiological Sciences
Apr 2008
Mar 2011
Postdoctoral Fellow, Researcher, Research Center for Charged Particle Therapy, National Institute of Radiological Sciences


Apr 2004
Mar 2008
Department of Advanced Medical Sciences, Graduate School of Medical and Pharmaceutical Sciences, University of Chiba
Apr 2002
Mar 2004
Department of Radiation Technology Science, Graduate School of Health Sciences, Ibaraki Prefectural University of Health Sciences
Apr 1998
Apr 2002
Department of Radiological Sciences, Faulty of Health & Medical Care,, Ibaraki Prefectural University of Health Sciences

Committee Memberships

Jan 2017
Dec 2017
Young Radiation Biologists' Association of Japan  Sub-steering committee
Jan 2016
Dec 2016
Young Radiation Biologists' Association of Japan  Sub-steering committee
Jan 2014
Dec 2014
Young Radiation Biologists' Association of Japan  Steering committee (workshop)
Jan 2013
Dec 2013
Young Radiation Biologists' Association of Japan  President
Jan 2012
Dec 2012
Young Radiation Biologists' Association of Japan  Vice-president

Awards & Honors

Jul 2007
Travel Support for Young Investigators of the 13th International Congress of Radiation Research, 13th International Congress of Radiation Research
Winner: Ryoichi Hirayama; Nobuo Kubota; Tatsuaki Kanai; Koichi Ando; Hirohiko Tsujii; Yoshiya Furusawa
(Introduction) Heavy-ion beams have good dose distribution for tumor. Carbon beams, accelerated by HIMAC in National Institute of Radiological Sciences (NIRS), is a candidate for use in hypofractionated radiotherapy of tumors included malignant me...
Oct 2009
Travel Support for Young Investigators of the 15th International Symposium on Microdosimetry, Micros 2009 - 15th International Symposium on Microdosimetry
Winner: Yoshitaka Matsumoto
The aim of this study is to clarify cell cycle distribution and cytotoxicity after carbon-ion beams (C-ions). One human malignant melanoma cell line, HMV-I was exposed to X-rays or 290 MeV/u C-ions at the center of SOBP. We applied flow cytometry ...
Sep 2014
41st Annual Meeting of the European Radiation Research Poster Award, The European Radiation Research Society
Winner: Nobuhiko Takai; Akiko Uzawa;Ryoichi Hirayama;Yoshitaka Matsumoto;Yoshihito Ohba;Saori Nakamura;Yoshiya Furusawa
The effects on the cognitive function and astrocytic activation in the hippocampus after local brain irradiation with carbon ions using mice
Oct 2016
JRR Terashima Award, Journal of Radiation Research
Winner: Yoshitaka Matsumoto: Take Matsuura: Mami Wada: Yusuke Egashira: Teiji Nishio: Yoshiya Furusawa
Nov 2017
Outstanding contributions to the development and advanced for Boron Neutron Capture Therapy., The Best Poster Presentation AWARD, 9th Young Researches’ BNCT Meeting
Winner: Yoshitaka Matsumoto

Published Papers

Furusawa, Y; Matsumoto, Y; Hirayama, R; Ohsawa, D; Konishi, T
Radiation protection dosimetry   Epub    Dec 2018
It is believed that the dose-rate of radiation will have an influence on cell sensitivity. The dose-rate effects on cell survival can be expressed by the change of the β term in the linear quadratic model. The value at a high-dose-rate decreases b...
Matsumoto, Yoshitaka; Ando, Koichi; Kato, Takamitsu A; Sekino, Yuta; Ishikawa, Hitoshi; Sakae, Takeji; Tsuboi, Koji; Sakurai, Hideyuki
Radiation protection dosimetry   Epub    Dec 2018
Fractionated proton beam radiotherapy is spreading worldwide these days. However, biological data of sub-lethal damage recovery (SLDR) after proton irradiation is not known yet. We here conducted split-dose experiments (20-360 min intervals) to cl...
Matsumoto, Yoshitaka; Furusawa, Yoshiya; Aoki-Nakano, Mizuho; Matsufuji, Naruhiro; Hirayama, Ryoichi; Kanai, Tatsuaki; Ando, Koichi; Sakurai, Hideyuki
Radiation protection dosimetry   Epub    Jan 2019
Hypofractionated carbon-ion therapy has been applied to treatment of several tumours. In this case, relative biological effectiveness (RBE) at high dose region must be considered, however, the RBE calculated physically has been not verified biolog...
松本孔貴;太田愛里;林淳子;関野雄太;福光延吉;斎藤高;石川, 仁;櫻井英幸
Thermal Medicine   33 140   2017
論文紹介(生物学) An analysis of the structure of the compound biological effectiveness factor
NCT Letter   (4) 26-28   Sep 2017
粒子線治療の生物効果を考える上で,従来のX線やγ線に比べた生物効果の違いを考慮することが重要である。普及を続ける炭素線や陽子線治療では,均一に照射される物理吸収線量に単一的なRBE値を乗じることで,生物学的X線等効果線量を算出している。しかし,ホウ素中性子捕捉療法(BNCT)の生物効果は腫瘍および正常組織へのホウ素化合物の集積に依存し,かつ集積性が臓器・組織毎に異なるため,従来前のRBEだけでは等効果線量の算出には不十分であり,そこで考案されたのがCBE(Compound Biolo...

Books etc

Radiation Biology to Learn from Mechanism of The Human Body
Matsumoto,Yoshitaka (Part:Contributor, Radiation Biology to Learn from Mechanism of The Human Body)
株式会社メジカルビュー社   Feb 2017   ISBN:9784758317252
新版 放射線医科学ー生体と放射線・電磁波・超音波ー
Matsumoto,Yoshitaka (Part:Contributor, 新版 放射線医科学ー生体と放射線・電磁波・超音波ー)
医療科学社   Oct 2016   ISBN:9784860034818
新版 放射線生物学
Matsumoto, Yoshitaka (Part:Contributor, 新版 放射線生物学)
株式会社 医療科学社   Dec 2015   ISBN:9784860034658
新版 放射線生物学
Matsumoto,Yoshitaka (Part:Contributor, 新版 放射線生物学)
株式会社 医療科学社   Dec 2015   ISBN:9784860034658

Conference Activities & Talks

Local drug delivery strategy empowers the reduced doses of both carboplatin and radiation to eradicate mouse subcutaneous melanoma.
Wang, Yuzi;Liang, Hsiang-Kuang;Sun, Lue;Matsumoto, Yoshitaka;Tsuboi, Koji
2019 ASCO Annual Meeting   31 May 2019   American Society of Clinical Oncology (ASCO)
Background: Radiotherapy (RT) is an essential treatment for high-risk cutaneous melanoma. Clinically, high-dose RT is adopted for melanoma treatment because of radioresistance; however, the side effects of RT, including skin ulcer and lymphedema, ...
大西かよ子;粟飯原輝人;石川, 仁;福光延吉;奥村敏之;水本斉志;松本孔貴;田中圭一;長野拓也;櫻井英幸
平成26年度京都大学原子炉実験所専門研究会   29 Sep 2014   
田中圭一;松本孔貴;石川, 仁;沼尻晴子;室伏景子;斎藤高;加沼玲子;大城佳子;奥村敏之;佐藤豊実
第19回癌治療増感研究シンポジウム   3 Feb 2017   
Biological effect clinical proton beams [Invited]
Matsumoto, Y;Furusawa, Y;Saito, T;Sekino, Y;Ando, K;Sakae, T;石川, 仁;Tsuboi, K;Sakurai, H
ISRN2018/第8回国際放射線神経生物学会大会   9 Feb 2018   
新規がん治療オンコサーミアによる放射線増感効果~治療抵抗性の克服に向けて~ [Invited]
松本, 孔貴;林, 淳子;関野, 雄太;福光, 延吉;斎藤, 高;石川, 仁;櫻井, 英幸
日本ハイパーサーミア学会第35回大会   30 Aug 2018   日本ハイパーサーミア学会

Teaching Experience


Research Grants & Projects

Verification of antitumor effect using BNCT nanoparticles for BNCT for improvement of treatment effect and expansion of adaptati
University of Tsukuba: 
Project Year: May 2017 - Mar 2018    Investigator(s): Yoshitaka Matsumoto