論文

査読有り 国際誌
2020年8月

Panomicon: A web-based environment for interactive, visual analysis of multi-omics data

Heliyon
  • Rodolfo S. Allendes Osorio
  • ,
  • Johan T. Nyström-Persson
  • ,
  • Yosui Nojima
  • ,
  • Yuji Kosugi
  • ,
  • Kenji Mizuguchi
  • ,
  • Yayoi Natsume-Kitatani

6
8
開始ページ
e04618
終了ページ
e04618
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1016/j.heliyon.2020.e04618
出版者・発行元
Elsevier BV

Multi-omics analyses, combining transcriptomics, genomics, proteomics, and so on, have led to important insights in many areas of biology and medicine. To support these analyses, software that can handle the difficulties associated with multi-omics datasets is crucial. Here, we describe Panomicon, a web-based, interactive analysis environment for multi-omics data. Building on Toxygates, a tool previously created to study single-omics data that features interactive clustering, heatmaps, and user data uploads, Panomicon introduces improvements for the storage and handling of additional omics types, as well as tools for the generation and visualization of interaction networks between different types of omics data. Panomicon is a new type of environment for the collaborative study of multi-omics data, both for users uploading data to our server and for groups wishing to host their own deployment of Panomicon. We demonstrate Panomicon's capabilities by revisiting a microRNA-mRNA interaction networks study in a non-small cell lung cancer dataset.

リンク情報
DOI
https://doi.org/10.1016/j.heliyon.2020.e04618
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/32904262
PubMed Central
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452437
ID情報
  • DOI : 10.1016/j.heliyon.2020.e04618
  • ISSN : 2405-8440
  • PubMed ID : 32904262
  • PubMed Central 記事ID : PMC7452437

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