佐久間裕司 (Yuji Sakuma) - マイポータル

基本情報

所属: 札幌医科大学医学部附属フロンティア医学研究所分子医学部門准教授

学位: 博士（医学）(自治医科大学)

研究者番号: 10364514
J-GLOBAL ID: 201401033731302107
researchmap会員ID: B000241814

外部リンク: http://kaken.nii.ac.jp/d/r/10364514.ja.html

研究キーワード

研究分野

ライフサイエンス / 人体病理学 /

経歴

2012年

地方独立行政法人神奈川県立病院機構神奈川県立がんセンター（臨床研究所）, がん分子病態学部, 副技幹

論文

The HSP90 inhibitor 17-N-allylamino-17-demethoxy geldanamycin (17-AAG) synergizes with cisplatin and induces apoptosis in cisplatin- resistant esophageal squamous cell carcinoma cell lines via the Akt/XIAP pathway

Takashi Ui, Kazue Morishima, Shin Saito, Yuji Sakuma, Hirofumi Fujii, Yoshinori Hosoya, Shumpei Ishikawa, Hiroyuki Aburatani, Masashi Fukayama, Toshiro Niki, Yoshikazu Yasuda

ONCOLOGY REPORTS 31(2) 619-624 2014年2月査読有り
Annexin A4 Is Involved in Proliferation, Chemo-Resistance and Migration and Invasion in Ovarian Clear Cell Adenocarcinoma Cells

Tae Mogami, Naho Yokota, Mikiko Asai-Sato, Roppei Yamada, Shiro Koizume, Yuji Sakuma, Mitsuyo Yoshihara, Yoshiyasu Nakamura, Yasuo Takano, Fumiki Hirahara, Yohei Miyagi, Etsuko Miyagi

PLOS ONE 8(11) e80359 2013年11月査読有り
Enhanced autophagy is required for survival in EGFR-independent EGFR-mutant lung adenocarcinoma cells

Yuji Sakuma, Shoichi Matsukuma, Yoshiyasu Nakamura, Mitsuyo Yoshihara, Shiro Koizume, Hironobu Sekiguchi, Haruhiro Saito, Haruhiko Nakayama, Yoichi Kameda, Tomoyuki Yokose, Sachiko Oguni, Toshiro Niki, Yohei Miyagi

Laboratory Investigation 93(10) 1137-1146 2013年10月査読有り
Downregulation of ALDH1A1 expression in non-small cell lung carcinomas - its clinicopathologic and biological significance

Koji Okudela, Tetsukan Woo, Hideaki Mitsui, Takeshisa Suzuki, Michihiko Tajiri, Yuji Sakuma, Yohei Miyagi, Yoko Tateishi, Shigeaki Umeda, Munetaka Masuda, Kenichi Ohashi

INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY 6(1) 1-12 2013年査読有り
Prognostic value of preoperative FDG-PET in stage IA lung adenocarcinoma

Shuji Murakami, Haruhiro Saito, Yuji Sakuma, Tetsuro Kondo, Fumihiro Oshita, Hiroyuki Ito, Masahiro Tsuboi, Chikako Hasegawa, Tomoyuki Yokose, Youichi Kameda, Haruhiko Nakayama, Kouzo Yamada

EUROPEAN JOURNAL OF RADIOLOGY 81(8) 1891-1895 2012年8月査読有り
HIF2α-Sp1 interaction mediates a deacetylation-dependent FVII-gene activation under hypoxic conditions in ovarian cancer cells.

Koizume S, Ito S, Miyagi E, Hirahara F, Nakamura Y, Sakuma Y, Osaka H, Takano Y, Ruf W, Miyagi Y

Nucleic acids research 40(12) 5389-5401 2012年7月査読有り
The Associations Between RAS Mutations and Clinical Characteristics in Follicular Thyroid Tumors: New Insights from a Single Center and a Large Patient Cohort

Michiko Fukahori, Akira Yoshida, Hiroyuki Hayashi, Mitsuyo Yoshihara, Shoichi Matsukuma, Yuji Sakuma, Shiro Koizume, Naoyuki Okamoto, Tetsuo Kondo, Munetake Masuda, Yohei Miyagi

THYROID 22(7) 683-689 2012年7月査読有り
NF-κB signaling is activated and confers resistance to apoptosis in three-dimensionally cultured EGFR-mutant lung adenocarcinoma cells.

Sakuma Y, Yamazaki Y, Nakamura Y, Yoshihara M, Matsukuma S, Koizume S, Miyagi Y

Biochemical and biophysical research communications 423(4) 667-671 2012年7月査読有り
Small bud of probable gastrointestinal stromal tumor within a laparoscopically-resected gastric schwannoma

Haruhiko Cho, Takafumi Watanabe, Toru Aoyama, Tsutomu Hayashi, Takanobu Yamada, Takashi Ogata, Takaki Yoshikawa, Akira Tsuburaya, Hironobu Sekiguchi, Yoshiyasu Nakamura, Yuji Sakuma, Yoichi Kameda, Yohei Miyagi

INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY 17(3) 294-298 2012年6月査読有り
Growth rate of lung cancer recognized as small solid nodule on initial CT findings

Kei Mikita, Haruhiro Saito, Yuji Sakuma, Tetsuro Kondo, Takeshi Honda, Syuji Murakami, Fumihiro Oshita, Hiroyuki Ito, Masahiro Tsuboi, Haruhiko Nakayama, Tomoyuki Yokose, Yoichi Kameda, Kazumasa Noda, Kouzo Yamada

EUROPEAN JOURNAL OF RADIOLOGY 81(4) E548-E553 2012年4月査読有り
Comparison of the Chemosensitivity of the Primary Lesion and a Pancreatic Metastasis of Colon Cancer: A Case Report

Hiroshi Tamagawa, Yohei Miyagi, Masakatsu Numata, Naoto Yamamoto, Manabu Shiozawa, Soichiro Morinaga, Akiko Sekiyama, Hironobu Sekiguchi, Yuji Sakuma, Yoichi Kameda, Makoto Akaike, Munetaka Masuda, Toshio Imada

ANTICANCER RESEARCH 32(4) 1457-1461 2012年4月査読有り
The global histone modification pattern correlates with overall survival in metachronous liver metastasis of colorectal cancer

Hiroshi Tamagawa, Takashi Oshima, Manabu Shiozawa, Soichiro Morinaga, Yoshiyasu Nakamura, Mitsuyo Yoshihara, Yuji Sakuma, Yoichi Kameda, Makoto Akaikei, Munetaka Masuda, Toshio Imada, Yohei Miyagi

ONCOLOGY REPORTS 27(3) 637-642 2012年3月査読有り
WZ4002, a third-generation EGFR inhibitor, can overcome anoikis resistance in EGFR-mutant lung adenocarcinomas more efficiently than Src inhibitors

Yuji Sakuma, Yukiko Yamazaki, Yoshiyasu Nakamura, Mitsuyo Yoshihara, Shoichi Matsukuma, Haruhiko Nakayama, Tomoyuki Yokose, Yoichi Kameda, Shiro Koizume, Yohei Miyagi

LABORATORY INVESTIGATION 92(3) 371-383 2012年3月査読有り
Stromal micropapillary component as a novel unfavorable prognostic factor of lung adenocarcinoma

Miki Ohe, Tomoyuki Yokose, Yuji Sakuma, Yohei Miyagi, Naoyuki Okamoto, Sachie Osanai, Chikako Hasegawa, Haruhiko Nakayama, Yoichi Kameda, Kouzo Yamada, Takeshi Isobe

DIAGNOSTIC PATHOLOGY 7 3 2012年1月査読有り
Differential detection of KRAS mutations in codons 12 and 13 with a modified loop-hybrid (LH) mobility shift assay using an insert-type LH-generator

Shoichi Matsukuma, Mitsuyo Yoshihara, Tetsuji Suda, Manabu Shiozawa, Makoto Akaike, Tomokazu Ishikawa, Shiro Koizume, Yuji Sakuma, Yohei Miyagi

CLINICA CHIMICA ACTA 412(19-20) 1874-1878 2011年9月査読有り
Stromal micropapillary pattern predominant lung adenocarcinoma - a report of two cases

Miki Ohe, Tomoyuki Yokose, Yuji Sakuma, Sachie Osanai, Chikako Hasegawa, Kota Washimi, Kimitoshi Nawa, Tetsukan Woo, Rurika Hamanaka, Haruhiko Nakayama, Yoichi Kameda, Kouzo Yamada, Takeshi Isobe

DIAGNOSTIC PATHOLOGY 6 92 2011年9月査読有り
Alveolar space filling ratio as a favorable prognostic factor in small peripheral squamous cell carcinoma of the lung

Yukihiro Watanabe, Tomoyuki Yokose, Yuji Sakuma, Chikako Hasegawa, Haruhiro Saito, Kozo Yamada, Hiroyuki Ito, Masahiro Tsuboi, Haruhiko Nakayama, Yoichi Kameda

LUNG CANCER 73(2) 217-221 2011年8月査読有り
Simple and precise detection of UGT1A1 polymorphisms with a modified loop-hybrid mobility shift assay using Cy5-labeled loop probes

Shoichi Matsukuma, Haruhiro Saito, Kozo Yamada, Naoyuki Okamoto, Tomokazu Ishikawa, Mitsuyo Yoshihara, Shiro Koizume, Yuji Sakuma, Yohei Miyagi

CLINICA CHIMICA ACTA 412(17-18) 1668-1672 2011年8月査読有り
Rare MDM4 gene amplification in colorectal cancer: The principle of a mutually exclusive relationship between MDM alteration and TP53 inactivation is not applicable

Tetsuji Suda, Mitsuyo Yoshihara, Yoshiyasu Nakamura, Hironobu Sekiguchi, Ten-I Godai, Nobuhiro Sugano, Kazuhito Tsuchida, Manabu Shiozawa, Yuji Sakuma, Eiju Tsuchiya, Yoichi Kameda, Makoto Akaike, Shoichi Matsukuma, Yohei Miyagi

ONCOLOGY REPORTS 26(1) 49-54 2011年7月査読有り
ABT-263, a Bcl-2 inhibitor, enhances the susceptibility of lung adenocarcinoma cells treated with Src inhibitors to anoikis

Yuji Sakuma, Jun Tsunezumi, Yoshiyasu Nakamura, Mitsuyo Yoshihara, Shoichi Matsukuma, Shiro Koizume, Yohei Miyagi

ONCOLOGY REPORTS 25(3) 661-667 2011年3月査読有り

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