論文

査読有り 招待有り 筆頭著者 最終著者 責任著者
2017年6月

Contraction and elongation: Mechanics underlying cell boundary deformations in epithelial tissue

DEVELOPMENT GROWTH & DIFFERENTIATION
  • Yusuke Hara

59
5
開始ページ
340
終了ページ
350
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1111/dgd.12356
出版者・発行元
WILEY

The cell-cell boundaries of epithelial cells form cellular frameworks at the apical side of tissues. Deformations in these boundaries, for example, boundary contraction and elongation, and the associated forces form the mechanical basis of epithelial tissue morphogenesis. In this review, using data from recent Drosophila studies on cell boundary contraction and elongation, I provide an overview of the mechanism underlying the bi-directionaldeformations in the epithelial cell boundary, that are sustained by biased accumulations of junctional and apico-medial non-muscle myosin II. Moreover, how the junctional tensions exist on cell boundaries in different boundary dynamics and morphologies are discussed. Finally, some future perspectives on how recent knowledge about single cell boundary-level mechanics will contribute to our understanding of epithelial tissue morphogenesis are discussed.

リンク情報
DOI
https://doi.org/10.1111/dgd.12356
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000406472300005&DestApp=WOS_CPL
ID情報
  • DOI : 10.1111/dgd.12356
  • ISSN : 0012-1592
  • eISSN : 1440-169X
  • ORCIDのPut Code : 33487425
  • Web of Science ID : WOS:000406472300005

エクスポート
BibTeX RIS