Yuki Sugiyama

Profile Information

J-GLOBAL ID: 201801018202836377
researchmap Member ID: B000340705

Research Interests

Research Areas

Research History

2017 - Present

Staff Scientist, Okinawa Institute of Science and Technology (Japan)
2008 - 2016

University of Sydney (Australia)
2006 - 2007

Postdoctoral fellow, Yokohama City University School of Medicine (Japan)
2004 - 2006

Research associate, University of Durham (UK)
2000 - 2003

Postdoctoral fellow, Yokohama City University School of Medicine (Japan)

Awards

2008

Endeavour Research Fellowship, Australian government

Yuki Sugiyama
2003

Travelling Research Fellowship, The Wellcome Trust (UK)

Yuki Sugiyama
2003

Foreign Research Fellowship, The Naito Foundation (Japan)

Yuki Sugiyama
2000

Postdoctoral Fellowship, The Japan Society for the Promotion of Science

Yuki Sugiyama

Papers

Intrinsic and extrinsic regulatory mechanisms are required to form and maintain a lens of the correct size and shape

J. W. McAvoy, L. J. Dawes, Y. Sugiyama, F. J. Lovicu

EXPERIMENTAL EYE RESEARCH, 156 34-40, Mar, 2017
Non-essential role for cilia in coordinating precise alignment of lens fibres

Yuki Sugiyama, Elizabeth J. Shelley, Bradley K. Yoder, Zbynek Kozmik, Helen L. May-Simera, Philip L. Beales, Frank J. Lovicu, John W. McAvoy

MECHANISMS OF DEVELOPMENT, 139 10-17, Feb, 2016
Atypical Cadherin Fat1 Is Required for Lens Epithelial Cell Polarity and Proliferation but Not for Fiber Differentiation

Yuki Sugiyama, Elizabeth J. Shelley, Caroline Badouel, Helen McNeill, John W. McAvoy

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 56(6) 4099-4107, Jun, 2015
Profiling of MicroRNAs Involved in Retinal Degeneration Caused by Selective Muller Cell Ablation

Sook Hyun Chung, Mark Gillies, Yuki Sugiyama, Ling Zhu, So-Ra Lee, Weiyong Shen

PLOS ONE, 10(3), Mar, 2015
Interactions between lens epithelial and fiber cells reveal an intrinsic self-assembly mechanism

L. J. Dawes, Y. Sugiyama, F. J. Lovicu, C. G. Harris, E. J. Shelley, J. W. McAvoy

DEVELOPMENTAL BIOLOGY, 385(2) 291-303, Jan, 2014
Sfrp1 and Sfrp2 are not involved in Wnt/beta-catenin signal silencing during lens induction but are required for maintenance of Wnt/beta-catenin signaling in lens epithelial cells

Yuki Sugiyama, Elizabeth J. Shelley, Li Wen, Richard J. W. Stump, Akihiko Shimono, Frank J. Lovicu, John W. McAvoy

DEVELOPMENTAL BIOLOGY, 384(2) 181-193, Dec, 2013
Wnt-Frizzled signaling is part of an FGF-induced cascade that promotes lens fiber differentiation

Lucy J. Dawes, Yuki Sugiyama, Ana S. Tanedo, Frank J. Lovicu, Frank J. Lovicu, John, W. McAvoy

Investigative Ophthalmology and Visual Science, 54 1582-1590, Mar 11, 2013
Analysis of PCP defects in mammalian eye lens

Yuki Sugiyama, John, W. McAvoy

Methods in Molecular Biology, 839 147-156, Feb 2, 2012
Planar cell polarity in the mammalian eye lens

Yuki Sugiyama, Frank J. Lovicu, John W. McAvoy

ORGANOGENESIS, 7(3) 191-201, Jul, 2011
Secreted frizzled-related protein disrupts PCP in eye lens fiber cells that have polarised primary cilia

Yuki Sugiyama, Richard J. W. Stump, Anke Nguyen, Li Wen, Yongjuan Chen, Yanshu Wang, Jennifer N. Murdoch, Frank J. Lovicu, John W. McAvoy

DEVELOPMENTAL BIOLOGY, 338(2) 193-201, Feb, 2010
A cell polarity protein aPKC lambda is required for eye lens formation and growth

Yuki Sugiyama, Kazunori Akimoto, Michael L. Robinson, Shigeo Ohno, Roy A. Quinlan

DEVELOPMENTAL BIOLOGY, 336(2) 246-256, Dec, 2009
NHS-A isoform of the NHS gene is a novel interactor of ZO-1

Shiwani Sharma, Katrina S. Y. Koh, Caitlin Collin, Alpana Dave, Amy McMellon, Yuki Sugiyama, John W. McAvoy, Anne K. Voss, Jozef Gecz, Jamie E. Craig

EXPERIMENTAL CELL RESEARCH, 315(14) 2358-2372, Aug, 2009
Symmetrically dividing cell specific division axes alteration observed in proteasome depleted C. elegans embryo

Yuki Sugiyama, Asuka Nishimura, Shigeo Ohno

MECHANISMS OF DEVELOPMENT, 125(8) 743-755, Aug, 2008
Expression and localisation of apical junctional complex proteins in lens epithelial cells

Yuki Sugiyama, Alan R. Prescott, Frederique M. D. Tholozan, Shigeo Ohno, Roy A. Quinlan

EXPERIMENTAL EYE RESEARCH, 87(1) 64-70, Jul, 2008
Mammalian LgI forms a protein complex with PAR-6 and aPKC independently of PAR-3 to regulate epithelial cell polarity

T Yamanaka, Y Horikoshi, Y Sugiyama, C Ishiyama, A Suzuki, T Hirose, A Iwamatsu, A Shinohara, S Ohno

CURRENT BIOLOGY, 13(9) 734-743, Apr, 2003
A novel integrin-linked kinase-binding protein, affixin, is involved in the early stage of cell-substrate interaction

S Yamaji, A Suzuki, Y Sugiyama, Y Koide, M Yoshida, H Kanamori, H Mohri, S Ohno, Y Ishigatsubo

JOURNAL OF CELL BIOLOGY, 153(6) 1251-1264, Jun, 2001
PAR-6 regulates aPKC activity in a novel way and mediates cell-cell contact-induces formation of the epithelial junctional complex

T. Yamanaka, Y. Horikoshi, A. Suzuki, Y. Sugiyama, K. Kitamura, R. Maniwa, Y. Nagai, A. Yamashita, T. Hirose, H. Ishikawa …

Genes to Cells, 6(8) 721-731, 2001
Muscle develops a specific form of small heat shock protein complex composed of MKBP/HSPB2 and HSPB3 during myogenic differentiation

Y Sugiyama, A Suzuki, M Kishikawa, R Akutsu, T Hirose, MMY Waye, SKW Tsui, S Yoshida, S Ohno

JOURNAL OF BIOLOGICAL CHEMISTRY, 275(2) 1095-1104, Jan, 2000
MKBP, a novel member of the small heat shock protein family, binds and activates the myotonic dystrophy protein kinase

A Suzuki, Y Sugiyama, Y Hayashi, N Nyu-i, M Yoshida, Nonaka, I, S Ishiura, K Arahata, S Ohno

JOURNAL OF CELL BIOLOGY, 140(5) 1113-1124, Mar, 1998
Direct sequencing of DNA fragments amplified with single primers by polymerase chain reaction without cloning

M Iizuka, Y Sugiyama, S Iida, T Sekiya

ANALYTICAL BIOCHEMISTRY, 241(1) 136-139, Oct, 1996

Misc.

水晶体上皮細胞の形態維持と増殖制御に非典型的カドヘリン蛋白 Fat1 が関与している

杉山由樹

日本白内障学会誌, 29 84, 2017 Peer-reviewedInvited
眼の水晶体 (レンズ) をつくる — 老眼や白内障を克服できるか?

杉山由樹

理大科学フォーラム, 9(9) 24-28, 2015 Peer-reviewedInvited
A muscle-specific stress-responsible system which is composed of diversed members of the small heat shock protein family

SUGIYAMA Y., SUZUKI A., KISHIKAWA M., AKUTSU R., HIROSE T., KATO K., WAYE Mary, OHNO S.

21 211-211, Dec 1, 1998
Induction of MST/MLK2 mRNA by heat shock

DEYAMA Tetsuya, YAMASHITA Akio, HIRAI Syu-ichi, SUGIYAMA Yuki, SUZUKI Atsushi, OHNO Shigeo

21 551-551, Dec 1, 1998

Presentations

Basement membrane regulates spheroidal shape formation of the vertebrate eye lens

Yuki Sugiyama

Annual Meeting of the Molecular Biology Society of Japan, Dec, 2020 Invited
Cell rearrangement and shape change cooperatively drive lens cell movement to form spherical tissue

Yuki Sugiyama

International Conference on the Lens (ICL), Dec, 2019 Invited
Cell rearrangement and shape change cooperatively drive lens cell movement to form a spherical tissue

Yuki Sugiyama

Molecular Biology Society of Japan Annual Meeting, Dec, 2019
Live-imaging of 4D dynamics of lens fibre cells

Yuki Sugiyama

International Zebrafish Conference, Jun, 2019
Live-imaging collective migration of lens fibre cells

Yuki Sugiyama

Association for Research in Vision and Ophthalmology (ARVO) annual meeting, Apr, 2019 Invited
Live-imaging of collective migration of lens fibre cells

Yuki Sugiyama

MEXT Grant-in-Aid for Scientific Research on Innovative Areas "Resonance Bio" International Joint Meeting on Bioimaging for Young Researchers, Oct, 2018 Invited
Fine tuning of ocular FGF activity regulates differentiation and collective movement of lens fibre cells

Yuki Sugiyama

International Society for Eye Research (ISER) Biennial Meeting, Sep, 2018 Invited
Fine tuning of ocular FGF activity regulates differentiation and collective movement of lens fibre cells

Yuki Sugiyama

Joint Meeting of Japan Society for Cell Biology (JSCB) & Japanese Society of Developmental Biologists (JSDB), Jun, 2018
Fine tuning of ocular FGF activity regulates lens fibre cell dynamics

Yuki Sugiyama

International Conference on the lens (ICL), Dec, 2017
How to form eye lens with precise spheroidal shape?

Yuki Sugiyama

East Asia Joint Symposium, Oct, 2017 Invited
Directed migration of lens fibre cells - a two-phase model

Yuki Sugiyama

Internal Society for Eye Research (ISER) Biennial Meeting, Sep, 2016 Invited
Is directed migration of the lens fibre cells led by guidance signals?

Yuki Sugiyama

International Conference on the lens (ICL), Dec, 2015 Invited
Planar cell polarity in the mammalian eye lens

Yuki Sugiyama

Annual Meeting of the Japanese Ophthalmological Society, Apr, 2015 Invited
Non-essential role for cilia in coordinating precise alignment of lens fibre

Yuki Sugiyama

Asia Association for Research in Vision and Ophthalmolog (ARVO) annual meeting, Feb, 2015
Regulation of lens formation and maintenance by primary cilia

Yuki Sugiyama

Internal Society for Eye Research (ISER) Biennial Meeting, Jul, 2014

Research Projects

Mechanobiological analysis of cell-basement membrane interaction during eye lens morphogenesis

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2021 - Mar, 2022

Profile Information

Research Interests

Research Areas

Research History

Awards

Papers

Misc.

Presentations

Research Projects

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