Arai Yasuyuki

Profile Information

Affiliation: Graduate School of Medicine, Kyoto University

ORCID ID: https://orcid.org/0000-0002-9662-5093
J-GLOBAL ID: 201801018973276462
researchmap Member ID: B000291749

External link: https://c-ract.kuhp.kyoto-u.ac.jp/

Research Interests

Research Areas

Life sciences / Hematology and oncology /

Research History

Aug, 2019

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Nov, 2018

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Apr, 2018

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Apr, 2015

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Apr, 2008

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Apr, 2006

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Education

Apr, 2011 - Mar, 2015

Graduate School of Medicine, Kyoto University
Apr, 2000 - Mar, 2006

Department of Medical Science, Faculty of Medicine, Kyoto University

Committee Memberships

Papers

CMV reactivation after allogeneic HCT is associated with a reduced risk of relapse in acute lymphoblastic leukemia.

Yu Akahoshi, Hideki Nakasone, Katsuto Takenaka, Satoshi Yamasaki, Momoko Nakamura, Noriko Doki, Masatsugu Tanaka, Yukiyasu Ozawa, Naoyuki Uchida, Takahide Ara, Hirohisa Nakamae, Shuichi Ota, Makoto Onizuka, Shingo Yano, Junji Tanaka, Takahiro Fukuda, Yoshinobu Kanda, Yoshiko Atsuta, Shinichi Kako, Masamitsu Yanada, Yasuyuki Arai

Blood advances, Jan 20, 2023
Significance of Omitting Day 11 Mini-Dose Methotrexate for GVHD Prophylaxis After Unrelated Bone Marrow Transplantation

Naokazu Nakamura, Fumiya Wada, Tadakazu Kondo, Kazunari Aoki, Yasuyuki Arai, Chisaki Mizumoto, Junya Kanda, Toshio Kitawaki, Kouhei Yamashita, Akifumi Takaori-Kondo

Transplantation and Cellular Therapy, Nov, 2022
Decreased serum phosphate levels are a useful biomarker to predict occurrence and severity of cytokine release syndrome in chimeric antigen receptor T ‐cell therapy

Naokazu Nakamura, Yasuyuki Arai, Toshio Kitawaki, Tomoyasu Jo, Chisaki Mizumoto, Junya Kanda, Momoko Nishikori, Kouhei Yamashita, Akifumi Takaori‐Kondo

British Journal of Haematology, Oct 11, 2022
Belt electrode-skeletal muscle electrical stimulation during early hematopoietic post-transplantation to prevent skeletal muscle atrophy and weakness.

Ryota Hamada, Susumu Sato, Junsuke Miyasaka, Masanobu Murao, Michiko Matsushita, Taishi Kajimoto, Ayumi Otagaki, Tsugumi Asano, Manabu Nankaku, Tadakazu Kondo, Yasuyuki Arai, Junya Kanda, Akifumi Takaori-Kondo, Ryosuke Ikeguchi, Shuichi Matsuda

Transplantation and cellular therapy, 29(1) 51.e1-51.e7, Oct 7, 2022
Activation of nucleotide-binding oligomerization domain 2 by muramyl dipeptide negatively regulates Toll-like receptor 9-mediated colonic inflammation through the induction of deubiquitinating enzyme A expression

Yasuhiro Masuta, Kosuke Minaga, Masayuki Kurimoto, Ikue Sekai, Akane Hara, Naoya Omaru, Natsuki Okai, Yasuo Otsuka, Ryutaro Takada, Tomoe Yoshikawa, Sho Masaki, Ken Kamata, Hajime Honjo, Yasuyuki Arai, Kouhei Yamashita, Masatoshi Kudo, Tomohiro Watanabe

International Immunology, Sep 29, 2022
iPLAT1: The first-in-human clinical trial of iPSC-derived platelets as a phase 1 autologous transfusion study.

Naoshi Sugimoto, Junya Kanda, Sou Nakamura, Toshiyuki Kitano, Masakatsu Hishizawa, Tadakazu Kondo, Shin Shimizu, Akiko Shigemasa, Hideyo Hirai, Yasuyuki Arai, Manabu Minami, Harue Tada, Dai Momose, Ki-Ryang Koh, Masayuki Nogawa, Naohide Watanabe, Shinichiro Okamoto, Makoto Handa, Akira Sawaguchi, Nobuki Matsuyama, Mitsunobu Tanaka, Tomoya Hayashi, Akihiro Fuchizaki, Yoshihiko Tani, Akifumi Takaori-Kondo, Koji Eto

Blood, Sep 16, 2022
Overcoming minimal residual disease using intensified conditioning with medium-dose etoposide, cyclophosphamide and total body irradiation in allogeneic stem cell transplantation for Philadelphia chromosome-positive acute lymphoblastic leukemia in adults.

Kaito Harada, Mari Morita-Fujita, Takahiro Fukuda, Yukiyasu Ozawa, Noriko Doki, Masako Toyosaki, Yumiko Maruyama, Yoshinobu Kanda, Takashi Ashida, Tetsuya Eto, Satoru Takada, Naoyuki Uchida, Tatsuo Ichinohe, Junya Kanda, Makoto Onizuka, Yoshiko Atsuta, Shinichi Kako, Yasuyuki Arai

Cytotherapy, 24(9) 954-961, Sep, 2022
Favorable Outcome with Conditioning Regimen of Flu/Bu4/Mel in Acute Myeloid Leukemia Patients in Remission Undergoing Cord Blood Transplantation.

Shohei Mizuno, Akiyoshi Takami, Koji Kawamura, Yoshimitsu Shimomura, Yasuyuki Arai, Takaaki Konuma, Yukiyasu Ozawa, Masashi Sawa, Shuichi Ota, Satoshi Takahashi, Naoyuki Anzai, Nobuhiro Hiramoto, Makoto Onizuka, Hirohisa Nakamae, Masatsugu Tanaka, Makoto Murata, Takafumi Kimura, Junya Kanda, Takahiro Fukuda, Yoshiko Atsuta, Masamitsu Yanada

Transplantation and cellular therapy, 28(11) 775.e1-775.e9, Aug 1, 2022
Relative hypercoagulation induced by suppressed fibrinolysis after tisagenlecleucel infusion in malignant lymphoma.

Makiko Yamasaki-Morita, Yasuyuki Arai, Takashi Ishihara, Tomoko Onishi, Hanako Shimo, Kayoko Nakanishi, Yukiko Nishiyama, Tomoyasu Jo, Hidefumi Hiramatsu, Takaya Mitsuyoshi, Chisaki Mizumoto, Junya Kanda, Momoko Nishikori, Toshio Kitawaki, Keiji Nogami, Akifumi Takaori-Kondo, Miki Nagao, Souichi Adachi

Blood advances, 6(14) 4216-4223, Jul 26, 2022
Effects of combined test-dose and therapeutic drug monitoring strategy in exposure-directed busulfan

Tomoki Iemura, Tadakazu Kondo, Atsushi Ueda, Takeshi Maeda, Toshio Kitawaki, Yasuyuki Arai, Junya Kanda, Takashi Ikeda, Kazunori Imada, Takayuki Ishikawa, Naoyuki Anzai, Mitsuru Itoh, Tomoharu Takeoka, Takashi Akasaka, Kazuhiro Yago, Akihito Yonezawa, Nobuyoshi Arima, Toshiyuki Kitano, Masaharu Nohgawa, Mitsumasa Watanabe, Toshinori Moriguchi, Kouhei Yamashita, Yasunori Ueda, Kana Matsumoto, Akifumi Takaori-Kondo

Jul 5, 2022
Adult patients with Ph+ ALL benefit from conditioning regimen of medium-dose VP16 plus CY/TBI.

Mari Morita-Fujita, Yasuyuki Arai, Tadakazu Kondo, Kaito Harada, Naoyuki Uchida, Takashi Toya, Yukiyasu Ozawa, Takahiro Fukuda, Shuichi Ota, Makoto Onizuka, Yoshinobu Kanda, Yumiko Maruyama, Satoru Takada, Toshiro Kawakita, Takahide Ara, Tatsuo Ichinohe, Takafumi Kimura, Yoshiko Atsuta, Shinichi Kako

Hematological oncology, Jul 5, 2022
Addition and drug monitoring of mycophenolate mofetil for GVHD prophylaxis in unrelated bone marrow transplantation

Fumiya Wada, Tadakazu Kondo, Ryusuke Yamamoto, Takero Yamagiwa, Yasuyuki Arai, Chisato Mizumoto, Junya Kanda, Toshio Kitawaki, Kouhei Yamashita, Akifumi Takaori-Kondo

Bone Marrow Transplantation, Jul, 2022
A Clinically Applicable Prediction Model to Improve T Cell Collection in Chimeric Antigen Receptor T Cell Therapy.

Tomoyasu Jo, Satoshi Yoshihara, Asuka Hada, Yasuyuki Arai, Toshio Kitawaki, Junko Ikemoto, Hitomi Onomoto, Hiroki Sugiyama, Kyoko Yoshihara, Natsuno Obi, Keiko Matsui, Norimi Niwa, Yoko Nakagawa, Junya Kanda, Tadakazu Kondo, Satoshi Saida, Itaru Kato, Hidefumi Hiramatsu, Souichi Adachi, Junko Takita, Akifumi Takaori-Kondo, Miki Nagao

Transplantation and cellular therapy, 28(7) 365.e1-365.e7, Jul, 2022
Improvements in allogeneic hematopoietic cell transplantation outcomes for adults with ALL over the past 3 decades.

Satoshi Nishiwaki, Yu Akahoshi, Mari Morita-Fujita, Hiroaki Shimizu, Naoyuki Uchida, Yukiyasu Ozawa, Takahiro Fukuda, Masatsugu Tanaka, Kazuhiro Ikegame, Shuichi Ota, Yuta Katayama, Satoshi Takahashi, Toshiro Kawakita, Takahide Ara, Makoto Onizuka, Takafumi Kimura, Junji Tanaka, Yoshiko Atsuta, Yasuyuki Arai

Blood advances, 6(15) 4558-4569, Jun 23, 2022
Intramuscular adipose tissue content predicts patient outcomes after allogeneic hematopoietic stem cell transplantation.

Ryota Hamada, Tsugumi Asano, Masanobu Murao, Junsuke Miyasaka, Michiko Matsushita, Taishi Kajimoto, Ayumi Otagaki, Manabu Nankaku, Yasuyuki Arai, Junya Kanda, Tadakazu Kondo, Akifumi Takaori-Kondo, Ryosuke Ikeguchi, Shuichi Matsuda

Transplantation and cellular therapy, Jun 19, 2022
Advantages of peripheral blood stem cells from unrelated donors versus bone marrow transplants in outcomes of adult acute myeloid leukemia patients

Tomoyasu Jo, Yasuyuki Arai, Tadakazu Kondo, Shohei Mizuno, Shigeki Hirabayashi, Yoshihiro Inamoto, Noriko Doki, Takahiro Fukuda, Yukiyasu Ozawa, Yuta Katayama, Yoshinobu Kanda, Kentaro Fukushima, Ken-ichi Matsuoka, Satoru Takada, Masashi Sawa, Takashi Ashida, Makoto Onizuka, Tatsuo Ichinohe, Yoshiko Atsuta, Junya Kanda, Masamitsu Yanada

Cytotherapy, 24(10) 1013-1025, Jun, 2022
Improved trends in survival and engraftment after single cord blood transplantation for adult acute myeloid leukemia.

Takaaki Konuma, Shohei Mizuno, Tadakazu Kondo, Yasuyuki Arai, Naoyuki Uchida, Satoshi Takahashi, Masatsugu Tanaka, Takuro Kuriyama, Shigesaburo Miyakoshi, Makoto Onizuka, Shuichi Ota, Yasuhiro Sugio, Yasushi Kouzai, Toshiro Kawakita, Hikaru Kobayashi, Yukiyasu Ozawa, Takafumi Kimura, Tatsuo Ichinohe, Yoshiko Atsuta, Masamitsu Yanada

Blood cancer journal, 12(5) 81-81, May 25, 2022
Coexistence of HLA and KIR ligand mismatches as a risk factor for viral infection early after cord blood transplantation

Tomoki Iemura, Yasuyuki Arai, Toshio Kitawaki, Junya Kanda, Tadakazu Kondo, Yasunori Ueda, Takuto Mori, Kazunori Imada, Akihito Yonezawa, Kazuhiro Yago, Naoyuki Anzai, Shinichi Kotani, Masaharu Nohgawa, Toshiyuki Kitano, Mitsuru Itoh, Nobuyoshi Arima, Toshinori Moriguchi, Mitsumasa Watanabe, Masaaki Tsuji, Kouhei Yamashita, Akifumi Takaori-Kondo

Bone Marrow Transplantation, May, 2022
Allogeneic Hematopoietic Stem Cell Transplantation for Adult Philadelphia Chromosome-Negative B-Cell Acute Lymphoblastic Leukemia in Second Complete Remission.

Satoshi Kaito, Shuhei Kurosawa, Yuho Najima, Emiko Sakaida, Naoki Shingai, Takahiro Fukuda, Takayoshi Tachibana, Naoyuki Uchida, Yukiyasu Ozawa, Masashi Sawa, Hideyuki Nakazawa, Shuichi Ota, Jun Kato, Hirohisa Nakamae, Yuta Katayama, Tetsuya Eto, Junji Tanaka, Yoshinobu Kanda, Yoshiko Atsuta, Yasuyuki Arai, Shinichi Kako

Transplantation and cellular therapy, 28(6) 326.e1-326.e10, Mar 17, 2022
Evaluation of indices for predicting recovery of exercise tolerance in patients surviving allogenic hematopoietic stem cell transplantation.

Ryota Hamada, Tadakazu Kondo, Kazuhiro Harada, Masanobu Murao, Junsuke Miyasaka, Michiko Yoshida, Honami Yonezawa, Manabu Nankaku, Yasuyuki Arai, Junya Kanda, Akifumi Takaori-Kondo, Ryosuke Ikeguchi, Shuichi Matsuda

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, Jan 22, 2022

Misc.

ABO不適合同種造血幹細胞移植症例の血液型検査結果の推移についての検討

岩本美紀, 万木紀美子, 菱田理恵, 濱野京子, 高折晃史, 城友泰, 新井康之, 長尾美紀

日本輸血細胞治療学会誌, 67(1) 81-82, Feb, 2021
Spectra Optiaおよびボルベン注6%を用いた顆粒球採取の検討

濱野京子, 万木紀美子, 平井秀世, 菱田理恵, 岩本美紀, 城友泰, 新井康之, 長尾美紀

日本輸血細胞治療学会誌, 67(1) 85-85, Feb, 2021
The impact of WBC at diagnosis for Ph-positive ALL in patients with negative-MRD at HCT

赤星佑, 新井康之, 西脇聡史, 立花崇孝, 篠原明仁, 土岐典子, 内田直之, 田中正嗣, 神田善伸, 神田善伸, 白鳥聡一, 小澤幸泰, 鐘野勝洋, 片山雄太, 田中淳司, 福田隆浩, 熱田由子, 熱田由子, 賀古真一

日本血液学会学術集会抄録(Web), 83rd, 2021
リンパ球クロスマッチとHLA抗体検査結果に乖離が見られた症例について

濱野京子, 万木紀美子, 秦浩一郎, 菱田理恵, 西山有紀子, 城友泰, 新井康之, 長尾美紀

日本輸血細胞治療学会誌, 67(2), 2021
Spectra Optiaおよびボルベン注6%を用いた顆粒球採取の検討

万木紀美子, 菱田理恵, 濱野京子, 澁谷江里香, 西山有紀子, 新井康之, 平位秀世, 長尾美紀

日本輸血細胞治療学会誌, 66(2) 341-341, May, 2020
ABO不適合同種造血幹細胞移植症例の血液型検査結果の推移についての検討

濱野京子, 新井康之, 万木紀美子, 菱田理恵, 澁谷江里香, 西山有紀子, 高折晃史, 平位秀世, 長尾美紀

日本輸血細胞治療学会誌, 66(2) 389-389, May, 2020
当院におけるチサゲンレクルユーセル(キムリア)用単核球の細胞処理の現状と問題点

丹羽紀実, 松井恵子, 中川陽子, 澁谷江里香, 新井康之, 平位秀世, 西山有紀子, 長尾美紀

日本輸血細胞治療学会誌, 66(2) 404-404, May, 2020
同種移植前後にgilteritinibを投与したFLT3-ITD変異陽性治療抵抗性急性骨髄性白血病の1例

虎谷和則, 光吉貴哉, 家村知樹, 新井康之, 近藤忠一, 山下浩平, 高折晃史

臨床血液, 61(2) 193-193, Feb, 2020
Ph-positive ALLにおける移植時MRDレベルの臨床的意義

赤星佑, 新井康之, 西脇聡史, 水田秀一, 土岐典子, 内田直之, 神田善伸, 神田善伸, 藤澤信, 酒井均, 田中淳司, 福田隆浩, 熱田由子, 賀古真一

日本血液学会学術集会抄録(Web), 82nd, 2020
50歳以上かつ移植時MRD陰性のPh染色体陽性ALL症例における前処置強度の影響

赤星佑, 西脇聡史, 新井康之, 原田介斗, 名島悠峰, 神田善伸, 神田善伸, 鐘野勝洋, 太田秀一, 福田隆浩, 内田直之, 田中淳司, 熱田由子, 賀古真一

日本血液学会学術集会抄録(Web), 82nd, 2020
LABScreen Single Antigen Beads法を用いて検出したドナー特異HLA抗体とFCM法リンパ球クロスマッチの相関について

菱田理恵, 万木紀美子, 澁谷江里香, 大野志織, 新井康之, 平位秀世

MHC: Major Histocompatibility Complex, 26(1) 48-48, Apr, 2019
当院におけるHLAタイピング検査結果表記法の検討

万木紀美子, 菱田理恵, 澁谷江里香, 大野志織, 新井康之, 平位秀世

MHC: Major Histocompatibility Complex, 26(1) 52-52, Apr, 2019
抗PP1Pkが検出された1症例

澁谷江里香, 万木紀美子, 菱田理恵, 大野志織, 新井康之, 平位秀世

日本輸血細胞治療学会誌, 65(2) 457-457, Apr, 2019
ドナー特異HLA抗体のMFI値とFCM法リンパ球クロスマッチの相関について

万木紀美子, 菱田理恵, 澁谷江里香, 大野志織, 新井康之, 平位秀世

日本輸血細胞治療学会誌, 65(2) 344-344, Apr, 2019
c-kitを標的としたキメラ抗原受容体T細胞(CAR-T)による新規骨髄移植前処置の開発(Myeloid conditioning with c-kit-targeted CAR-T enables donor hematopoietic stem cell engraftment)

新井康之, Malech Harry, 高折晃史

臨床血液, 59(9) 1587-1587, Sep, 2018
あなたの日常診療を科学にしようAccepted Paper Session-臨床研究の着想から論文アクセプトまで成功体験を共有する- 臨床疫学研究の出口戦略お蔵入り論文ゼロを目指すために

新井康之

日本化学療法学会雑誌, 66(Suppl.A) 192-192, Apr, 2018
Adolescents and Young Adults with Acute Myeloid Leukemia Are Associated with Higher Treatment-Related Mortality and Inferior Overall Survival after Allogeneic Hematopoietic Cell Transplantation Compared with Children

Daisuke Tomizawa, Shiro Tanaka, Tadakazu Kondo, Yoshiko Hashii, Yasuyuki Arai, Kazuko Kudo, Takashi Taga, Jiro Inagaki, Katsuyoshi Koh, Masami Inoue, Junji Tanaka, Koji Kato, Yoshiko Atsuta, Souichi Adachi, HIroyuki Ishida

BLOOD, 128(22), Dec, 2016
Efficacy of high-dose cytarabine added to CY/TBI in CBT for myeloid malignancy

72(3) 318-321, Mar, 2016
遺伝子組み換え型ヒトトロンボモジュリン製剤が有効であった血球貪食症候群併発播種性血管内凝固

山崎寛章, 近藤忠一, 辰巳剛一, 小谷槙一, 新井康之, 白川康太郎, 北野俊行, 菱澤方勝, 門脇則光, 高折晃史

臨床血液, 56(3) 312-316, Mar, 2015
TRUMPデータを用いた,肝臓急性移植片対宿主病発症リスク因子の解析

新井康之, 諫田淳也, 仲宗根秀樹, 近藤忠一, 内田直之, 福田隆浩, 大橋一輝, 小川啓恭, 長村登紀子, 森島泰雄, 廣川誠, 熱田由子, 村田誠

日本造血細胞移植学会総会プログラム・抄録集, 37th 221, Feb 6, 2015

Research Projects

Machine-learning based approach for cellular therapy in hematological malignancy

Grants-in-Aid for Scientific Research Grant-in-Aid for Early-Career Scientists, Japan Society for the Promotion of Science, Apr, 2022 - Mar, 2025
造血幹細胞移植後の腸内細菌叢変化に着目した、腸管GVHD発症の新規予防法の開発

科学研究費助成事業若手研究, 日本学術振興会, Apr, 2019 - Mar, 2022

新井康之
Myeloid conditioning using chimeric antigen receptor T cells

Grants-in-Aid for Scientific Research Grant-in-Aid for Research Activity Start-up, Japan Society for the Promotion of Science, Aug, 2018 - Mar, 2020

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