論文

査読有り 国際誌
2018年11月21日

Isolated Fornix Infarction with Damage to the Limbic System as a Cause of Persistent Amnesia: A Case Report.

The American journal of case reports
  • Yumi Takano
  • ,
  • Yasuko Tatewaki
  • ,
  • Tatsushi Mutoh
  • ,
  • Yamato Ohara
  • ,
  • Shuzo Yamamoto
  • ,
  • Yasuyuki Taki

19
開始ページ
1382
終了ページ
1385
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.12659/AJCR.912508

BACKGROUND The fornix is a white matter tract bundle that acts as the major output of the hippocampus and is an important component of the Papez circuit. We present an instructive imaging case of sudden onset of persistent amnesia due to selective ischemic damage of the anterior fornix. CASE REPORT A 54-year-old Japanese male came to our attention for a sudden onset of retrograde amnesia, associated with severe anterograde amnesia. The brain magnetic resonance imaging demonstrated a bright diffusion restriction, which was associated with swollen fornices bilaterally. His symptoms gradually improved, but episodic memory impairment still persisted after 1 month. The coronal T1-weighted MPRAGE (magnetization-prepared rapid acquisition with gradient echo) sequence clearly showed disruption of the left anterior fornix. Diffusion tensor tracking showed decrease in the density of entire fiber tracts on the Papez circuit as well as location of the left fornix. CONCLUSIONS When dealing with sudden, persistent amnesia associated with small fornix infarction, it is prudent to consider the possibility of tract damage along with limbic system damage using MPRAGE sequence.

リンク情報
DOI
https://doi.org/10.12659/AJCR.912508
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/30459298
PubMed Central
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6266538
ID情報
  • DOI : 10.12659/AJCR.912508
  • PubMed ID : 30459298
  • PubMed Central 記事ID : PMC6266538

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