Yujiro Hattori

Profile Information

Affiliation: 日本医科大学

Degree: M.D.(Keio University)
Ph.D.(Graduate School of Medicine, Nippon Medical School)

J-GLOBAL ID: 201801002476977097
researchmap Member ID: B000295473

Board Certified Neurosurgeon
Board Certified Pediatrician
Board Certified Endocrinologist

I conduct basic and clinical research on pituitary tumors and pituitary related diseases.

Research Interests

Research Areas

Research History

Jan, 2023 - Present

Postdoctoral Scientist, (Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism), Cedars-Sinai Medical Center
Apr, 2018 - Present

Senior Assistant Professor, Nippon Medical School Department of Anatomy and Neurobiology / Neurosurgery, Graduate School of Medicine
Apr, 2017 - Mar, 2018

Assistant Professor, Nippon Medical School Department of Anatomy and Neurobiology / Neurosurgery, Graduate School of Medicine
Jun, 2016 - Mar, 2017

Assistant Professor, Nippon Medical School Department of Neurosurgery / Anatomy and Neurobiology
May, 2016 - May, 2016

Assistant Professor, Neurosurgery, Nippon Medical School
Apr, 2012 - Apr, 2016

Graduate Student, Graduate School, Nippon Medical School
Apr, 2008 - Mar, 2012

Pediatrics, Keio University
Apr, 2006 - Mar, 2008

Junior Resident, Hiratsuka City Hospital
Nippon Medical School

Education

Apr, 2012 - Apr, 2016

Nippon Medical School, Graduate School of Medicine
Apr, 2000 - Mar, 2006

School of Medicine, Keio University

Committee Memberships

Apr, 2020 - Present

Councilor, The Japan Endocrine Society
Feb, 2019 - Present

Councilor, The Japanese Society for Hypothalamic and Pituitary tumors
Aug, 2016 - Present

Councilor, The Japan Neurosurgical Society

Awards

2023

25th Japan Society of Histochemistry and Cytochemistry Paper Award

Mina Ozawa, Yujiro Hattori (co-first author), Shimpei Higo, Mai Otsuka, Keisuke Matsumoto, Hitoshi Ozawa, Hirotaka Ishii
2022

Nippon Medical School Young Researchers Award
2021

31rd Research Encouragement Award of the Japanese society for Hypothalamic and Pituitary tumors
2018

28th JES Clinical Update Award
2017

Nippon Medical School reunion Medical Research Grant
2015

42nd annual meeting of the Japan neuroendocrine society Travel Grant
2014

24th JES Clinical Update Award
2013

40th annual meeting of the Japan neuroendocrine society Travel Award
2013

Yamada Osamitsu Scholarship Foundation
2012

8th Acromegaly Forum Encouragement Award

Papers

Lung adenocarcinoma metastasis within a pituitary neuroendocrine tumor: a case report with review of literature.

Koji Suzuki, Shigeyuki Tahara, Yujiro Hattori, Shinichiro Teramoto, Eitaro Ishisaka, Chie Inomoto, Robert Yoshiyuki Osamura, Akio Morita, Yasuo Murai

Endocrine journal, Dec 29, 2023 Peer-reviewed
Endoscopic spinal cord untethering using a 1 cm skin incision technique in pediatrics: a technical case report.

Eitaro Ishisaka, Shigeyuki Tahara, Atsushi Tsukiyama, Toshiki Nozaki, Yujiro Hattori, Akio Morita, Yasuo Murai

BMC pediatrics, 23(1) 604-604, Nov 29, 2023 Peer-reviewed
Comparison of prophylactic antibiotics for endonasal transsphenoidal surgery using a national inpatient database in Japan.

Yujiro Hattori (corresponding), Shigeyuki Tahara, Shotaro Aso, Kanako Makito, Hiroki Matsui, Kiyohide Fushimi, Hideo Yasunaga, Akio Morita

The Journal of antimicrobial chemotherapy, 78(12) 2909-2914, Oct 19, 2023 Peer-reviewedLead authorCorresponding author
Endoscopic surgery versus craniotomy for spontaneous intracerebral hemorrhage in the late elderly patients.

Shigeyuki Tahara, Yujiro Hattori, Shotaro Aso, Kazuaki Uda, Ryosuke Kumazawa, Hiroki Matsui, Kiyohide Fushimi, Hideo Yasunaga, Akio Morita

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 32(11) 107327-107327, Sep 5, 2023 Peer-reviewed
Assessment of anterior pituitary reserve capacity based on growth hormone response to growth hormone-releasing peptide-2 test in the elderly

Shinichiro Teramoto, Shigeyuki Tahara, Yujiro Hattori, Akihide Kondo, Akio Morita

Growth Hormone & IGF Research, 71 101545-101545, Aug, 2023 Peer-reviewed
Exploring endocrinological pitfalls in pituitary surgery in the elderly

Shinichiro Teramoto, Shigeyuki Tahara, Izumi Fukuda, Yujiro Hattori, Akihide Kondo, Hitoshi Sugihara, Akio Morita

Heliyon, 9(6) e17060-e17060, Jun, 2023 Peer-reviewed
Concurrent IgG4-related hypophysitis and clinically nonfunctioning gonadotroph pituitary neuroendocrine tumor.

Shigeyuki Tahara, Robert Yoshiyuki Osamura, Yujiro Hattori, Eitaro Ishisaka, Chie Inomoto, Hitoshi Sugihara, Akira Teramoto, Akio Morita

BMC endocrine disorders, 23(1) 96-96, May 4, 2023 Peer-reviewed
Creation of low cost, simple, and easy-to-use training kit for the dura mater suturing in endoscopic transnasal pituitary/skull base surgery.

Yujiro Hattori (corresponding), Eitaro Ishisaka, Shigeyuki Tahara, Koji Suzuki, Shinichiro Teramoto, Akio Morita

Scientific reports, 13(1) 6073-6073, Apr 13, 2023 Peer-reviewedLead authorCorresponding author
Estrogen receptor α isoforms generated by alternative use of cryptic exons

Hirotaka Ishii, Yujiro Hattori, Hitoshi Ozawa

Journal of Nippon Medical School, 90(5) 364-371, 2023
Immunohistochemistry for ESR2 with a mouse monoclonal antibody (PPZ0506)

Masahiro Morishita, Shimpei Higo, Yujiro Hattori, Mina Ozawa, Mai Otsuka, Keisuke Matsumoto, Hitoshi Ozawa, Hirotaka Ishii

Journal of Nippon Medical School, 90(2) 138-140, 2023 Peer-reviewed
Outcomes After Endoscopic Evacuation Versus Evacuation Using Craniotomy or Stereotactic Aspiration for Spontaneous Intracerebral Hemorrhage: Analysis Using a Japanese Nationwide Database.

Shigeyuki Tahara, Yujiro Hattori, Shotaro Aso, Kazuaki Uda, Ryosuke Kumazawa, Hiroki Matsui, Kiyohide Fushimi, Hideo Yasunaga, Akio Morita

Neurocritical care, 38(3) 667-675, Nov 8, 2022 Peer-reviewed
Optimized Mouse-on-mouse Immunohistochemical Detection of Mouse ESR2 Proteins with PPZ0506 Monoclonal Antibody.

Mina Ozawa, Yujiro Hattori (co-first author), Shimpei Higo, Mai Otsuka, Keisuke Matsumoto, Hitoshi Ozawa, Hirotaka Ishii

Acta histochemica et cytochemica, 55(5) 159-168, Oct 28, 2022 Peer-reviewedLead author
An Overview of Pituitary Incidentalomas: Diagnosis, Clinical Features, and Management

Shigeyuki Tahara, Yujiro Hattori, Koji Suzuki, Eitaro Ishisaka, Shinichiro Teramoto, Akio Morita

Cancers, 14(17) 4324, Sep 3, 2022 Peer-reviewed
Trends in surgical procedures for spontaneous intracerebral hemorrhage in Japan.

Shigeyuki Tahara, Yujiro Hattori, Shotaro Aso, Kazuaki Uda, Ryosuke Kumazawa, Hiroki Matsui, Kiyohide Fushimi, Hideo Yasunaga, Akio Morita

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 31(9) 106664-106664, Jul 28, 2022 Peer-reviewed
Injury to the Extrasellar Portion of the Internal Carotid Artery during Endoscopic Transsphenoidal Surgery: A Case Report.

Shinichiro Teramoto, Shigeyuki Tahara, Yasuo Murai, Shun Sato, Yujiro Hattori, Akihide Kondo, Akio Morita

Frontiers in surgery, 9 895233-895233, 2022 Peer-reviewed
Prophylactic steroid administration and complications after transsphenoidal pituitary surgery: a nationwide inpatient database study in Japan

Yujiro Hattori (corresponding), Shigeyuki Tahara, Shotaro Aso, Hiroki Matsui, Kiyohide Fushimi, Hideo Yasunaga, Akio Morita

British Journal of Anaesthesia, 127(2) e41-e43, Aug, 2021 Peer-reviewedLead authorCorresponding author
Bacterial Flora in the Sphenoid Sinus Changes with Perioperative Prophylactic Antibiotic Administration.

Eiichi Baba, Yujiro Hattori (co-first author), Shigeyuki Tahara, Akio Morita

Neurologia medico-chirurgica, 61(6) 361-366, Jun 15, 2021 Peer-reviewedLead author
Optimization of immunohistochemical detection of rat ESR2 proteins with well-validated monoclonal antibody PPZ0506.

Yujiro Hattori, Hirotaka Ishii, Shimpei Higo, Mai Otsuka, Moeko Kanaya, Keisuke Matsumoto, Mina Ozawa, Hitoshi Ozawa

Molecular and cellular endocrinology, 523 111145-111145, Mar 1, 2021 Peer-reviewedLead author
Snowfall reduces the risk of chronic subdural hematoma onset: Analysis of an administrative database in Japan.

Kazunori Oda, Shotaro Aso, Yujiro Hattori, Fumio Yamaguchi, Hiroki Matsui, Kiyohide Fushimi, Hideo Yasunaga, Akio Morita

Surgical neurology international, 12 69-69, 2021 Peer-reviewed
Quantitative expression data of human estrogen receptor α variants in non-functioning pituitary adenomas obtained by reverse transcription-digital polymerase chain reaction analysis.

Yujiro Hattori (corresponding), Hirotaka Ishii, Shigeyuki Tahara, Akio Morita, Hitoshi Ozawa

Data in brief, 33 106452-106452, Dec, 2020 Peer-reviewedLead authorCorresponding author

Misc.

114

自己免疫性下垂体炎に対する内視鏡下経鼻的生検術

築山敦, 田原重志, 石坂栄太郎, 服部裕次郎, 亦野文宏, 寺本紳一郎, 鈴木幸二, 福田いずみ, 井野元智恵, 長村義之 …

日本内分泌学会雑誌, 99(Suppl.HPT) 90-93, Aug, 2023
間脳下垂体機能障害と先天性腎性尿崩症および関連疾患の診療ガイドライン2023年版

有馬寛, 大月道夫, 蔭山和則, 高橋裕, 田原重志, 西山充, 槙田紀子, 水野晴夫, 山田正信, 有安宏之 …

日本内分泌学会雑誌, 99(Suppl.) i-171, Jul, 2023
TSH産生下垂体腫瘍の臨床病理学的特徴と長期成績

鈴木幸二, 田原重志, 服部裕次郎, 石坂栄太郎, 寺本紳一郎, 瓜生康浩, 宮原宏輔, 井野元智恵, 長村義之, 森田明夫

日本内分泌学会雑誌, 99(1) 350-350, May, 2023
自己免疫性下垂体炎に対する内視鏡下経鼻的生検術

築山敦, 田原重志, 石坂栄太郎, 服部裕次郎, 亦野文宏, 福田いずみ, 井野元智恵, 長村義之, 森田明夫

日本内分泌学会雑誌, 99(1) 358-358, May, 2023
抗ヒトERβ特異的モノクローナル抗体(PPZ0506)を用いたラット及びマウスERβタンパク質に対する免疫組織化学染色法の確立

服部裕次郎, 小澤実那, 肥後心平, 森下雅大, 大塚真衣, 松本恵介, 小澤一史, 石井寛高

日本内分泌学会雑誌, 98(5) 1398-1398, Mar, 2023
【どんな手術が、どんな手順で、どんな風に行われているかがとことんわかる!手術動画つき必要な術後看護がみえてくる脳神経外科の手術】(1章)脳神経外科の手術を理解するうえで知っておきたいこと解剖生理と機能局在視床

服部裕次郎, 田原重志

Brain Nursing, 39(1) 24-25, Jan, 2023
【どんな手術が、どんな手順で、どんな風に行われているかがとことんわかる!手術動画つき必要な術後看護がみえてくる脳神経外科の手術】(1章)脳神経外科の手術を理解するうえで知っておきたいこと解剖生理と機能局在視床下部・下垂体

服部裕次郎, 田原重志

Brain Nursing, 39(1) 26-27, Jan, 2023
【どんな手術が、どんな手順で、どんな風に行われているかがとことんわかる!手術動画つき必要な術後看護がみえてくる脳神経外科の手術】(1章)脳神経外科の手術を理解するうえで知っておきたいこと解剖生理と機能局在脳幹

服部裕次郎, 田原重志

Brain Nursing, 39(1) 28-29, Jan, 2023
【どんな手術が、どんな手順で、どんな風に行われているかがとことんわかる!手術動画つき必要な術後看護がみえてくる脳神経外科の手術】(1章)脳神経外科の手術を理解するうえで知っておきたいこと解剖生理と機能局在脳神経

服部裕次郎, 田原重志

Brain Nursing, 39(1) 30-31, Jan, 2023
抗ヒトERβ特異的モノクローナル抗体(PPZ0506)を用いたMouse-on-Mouse免疫組織化学染色法の最適化条件の決定およびマウスERβの局在解析

小澤実那, 服部裕次郎, 肥後心平, 大塚真衣, 松本恵介, 石井寛高, 小澤一史

日本医科大学医学会雑誌, 18(4) 447-448, Dec, 2022
GHRP-2を用いた高齢者下垂体予備能評価法の低侵襲化の検討

寺本紳一郎, 田原重志, 服部裕次郎, 近藤聡英, 森田明夫

日本内分泌学会雑誌, 98(2) 557-557, Oct, 2022
【高齢者の糖尿病・内分泌代謝疾患マネージメント】年齢を考慮した非機能性下垂体腺腫のマネージメント

鈴木幸二, 田原重志, 服部裕次郎, 寺本紳一郎, 森田明夫

糖尿病・内分泌代謝科, 55(3) 292-300, Sep, 2022
クッシング病に対し内視鏡下経鼻的手術後寛解が得られたが44ヵ月で再燃しOsilodrostatが有効であった一例

鈴木幸二, 田原重志, 服部裕次郎, 石坂栄太郎, 福田いずみ, 杉原仁, 森田明夫

日本内分泌学会雑誌, 98(1) 296-296, Apr, 2022
抗ヒトERβ特異的モノクローナル抗体(PPZ0506)を用いたマウス組織における免疫組織化学染色法の最適化とマウスERβタンパク質の発現・局在解析

小澤実那, 服部裕次郎, 石井寛高, 肥後心平, 大塚真衣, 松本恵介, 小澤一史

日本解剖学会総会・全国学術集会講演プログラム・抄録集, 127th (CD-ROM) 130-65, Mar, 2022
C末端欠損型ESR1アイソフォームの細胞内局在と構造-転写活性化連関

石井寛高, 服部裕次郎, 小澤一史

日本解剖学会総会・全国学術集会講演プログラム・抄録集, 127th (CD-ROM), 2022
内視鏡下経鼻的手術時の硬膜縫合用の安価な練習機作製の試み

服部裕次郎, 服部裕次郎, 石坂栄太郎, 鈴木幸二, 田原重志, 森田明夫

日本間脳下垂体腫瘍学会プログラム・抄録集, 32nd, 2022
著明な視路の浮腫性変化を呈した下垂体細胞腫の一例

鈴木幸二, 田原重志, 服部裕次郎, 石坂栄太郎, 森田明夫

日本間脳下垂体腫瘍学会プログラム・抄録集, 32nd, 2022
クッシング病に対する集学的治療と長期治療成績

田原重志, 服部裕次郎, 石坂栄太郎, 鈴木幸二, 寺本紳一郎, 福田いずみ, 杉原仁, 寺本明, 森田明夫

日本間脳下垂体腫瘍学会プログラム・抄録集, 32nd, 2022
Succession from microscope to endoscopic surgery and acquisition of techniques in transnasal tumor resection

田原重志, 服部裕次郎, 石坂栄太郎, 鈴木幸二, 寺本紳一郎, 喜多村孝幸, 寺本明, 森田明夫

日本神経内視鏡学会プログラム・抄録集, 28th 147, Nov, 2021
A case of pituicytoma with marked edematous changes in the optic tract

鈴木幸二, 田原重志, 服部裕次郎, 石坂栄太郎, 森田明夫

日本神経内視鏡学会プログラム・抄録集, 28th 137, Nov, 2021

Books and Other Publications

ブレインナーシング 2023年1号 <特集>手術動画つき必要な術後看護がみえてくる脳神経外科の手術（第39巻1号）

服部裕次郎, 田原重志 (Role: Contributor, ①解剖生理と機能局在 06視床, 07視床下部・下垂体, 08脳幹, 09脳神経)

メディカ出版, Dec, 2022 (ISBN: 4840479291)
糖尿病・内分泌代謝科

鈴木幸二, 田原重志, 服部裕次郎, 寺本紳一郎, 森田明夫 (Role: Contributor, 年齢を考慮した非機能性下垂体腺腫のマネージメント)

科学評論社, Sep, 2022
内分泌画像検査診断マニュアル改訂第２版

服部裕次郎, 田原重志 (Role: Contributor, 【Ⅱ各論編第2章視床下部・下垂体疾患】傍鞍部腫瘍)

診断と治療社, Dec, 2020
内分泌・糖尿病・代謝内科

服部裕次郎, 田原重志 (Role: Contributor, 【機能性内分泌疾患に対する外科治療と内科治療】クッシング病外科治療)

科学評論社, Nov, 2017
Clinical Neuroscience

服部裕次郎, 田原重志 (Role: Contributor, 【視床下部と下垂体-神経内分泌の最新情報】内分泌機能障害の診断と治療 SIADH(SIAD))

Apr, 2017
脳神経外科研修診療心得

服部裕次郎 (Role: Contributor, Ⅲ章脳腫瘍下垂体腫瘍)

メジカルビュー社, Oct, 2014

Teaching Experience

Major Professional Memberships

Research Projects

新WHO分類における下垂体神経内分泌腫瘍の悪性度に関与する因子の探索

科学研究費助成事業, 基盤研究(C), 日本学術振興会, Apr, 2023 - Mar, 2026

田原重志, 服部裕次郎
内視鏡下経鼻的手術における硬膜縫合のための安価かつ簡便な練習機の開発

2022年度研究助成B, 公益財団法人内視鏡医学研究振興財団, Jan, 2023 - Dec, 2023

服部裕次郎, 田原重志
プロラクチン産生下垂体腺腫における腫瘍発生・増殖を担う新規遺伝子の同定

科学研究費助成事業若手研究, 日本学術振興会, Apr, 2020 - Mar, 2023

服部裕次郎
ESR1アイソフォームによるエストロゲン感受性腫瘍の内分泌・化学療法耐性獲得機構

科学研究費助成事業基盤研究(C), 基盤研究(C), 日本学術振興会, Apr, 2018 - Mar, 2022

石井寛高, 服部裕次郎
Molecular and morphofunctional study on the novel regulation system for reproduction based on the input of various enviromental information

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2018 - Mar, 2021
ホルモン感受性腫瘍におけるエストロゲン受容体変異体の発現プロファイルの同定

科学研究費助成事業若手研究(B), 若手研究(B), 日本学術振興会, Apr, 2017 - Mar, 2020

服部裕次郎
ヒトエストロゲン受容体変異体の機能と発現調節機構の解明

2014年度教育・研究助成金, 日本イーライリリー株式会社, Apr, 2014 - Mar, 2015

服部裕次郎

Academic Activities

Certified Endocrine Educator (by JES)

Review, evaluation

Apr 1, 2023 - Present
Board Certified Supervisor of Pediatrics

Review, evaluation

Oct 1, 2016 - Present
7

Clinical Guidelines for Hypothalamic-Pituitary Dysfunction, Congenital Nephrogenic Diabetes Insipidus, and Related Disorders, 2023 Edition: systematic review

Planning/Implementing academic research

Jul, 2023 - Jul, 2023
Regular involvement in the peer review process for scientific papers, such as for the New England Journal of Medicine etc.

Peer review

Social Activities

日本救急医学会認定ICLSインストラクター

Lecturer

Apr, 2007 - Jan, 2018

Profile Information

Research Interests

Research Areas

Research History

Education

Committee Memberships

Awards

Papers

Misc.

Books and Other Publications

Teaching Experience

Major Professional Memberships

Research Projects

Academic Activities

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