2014年12月
A New Bis-seco-abietane Diterpenoid from Hyptis crenata Pohl ex Benth
ORGANIC LETTERS
- ,
- ,
- ,
- ,
- ,
- ,
- 巻
- 16
- 号
- 23
- 開始ページ
- 6188
- 終了ページ
- 6191
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1021/ol503086n
- 出版者・発行元
- AMER CHEMICAL SOC
A new, highly oxidized, bis-seco-abietane diterpenoid named hyptisolide A (1) was isolated from Hyptis crenata Pohl ex Benth. Its structure and stereochemistry were elucidated on the basis of data obtained by HRESIMS, NMR, and X-ray diffraction analyses, and its absolute configuration was determined with vibrational circular dichroism spectroscopy. By reporter gene assay, 1 was demonstrated to induce cAMP-responsive element-dependent transcription in Neuro2A cells.
- リンク情報
- ID情報
-
- DOI : 10.1021/ol503086n
- ISSN : 1523-7060
- eISSN : 1523-7052
- Web of Science ID : WOS:000346037500038