2013年9月
A cross-species socio-emotional behaviour development revealed by a multivariate analysis
SCIENTIFIC REPORTS
- 巻
- 3
- 号
- 開始ページ
- 2630
- 終了ページ
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1038/srep02630
- 出版者・発行元
- NATURE PUBLISHING GROUP
Recent progress in affective neuroscience and social neurobiology has been propelled by neuro-imaging technology and epigenetic approach in neurobiology of animal behaviour. However, quantitative measurements of socio-emotional development remains lacking, though sensory-motor development has been extensively studied in terms of digitised imaging analysis. Here, we developed a method for socio-emotional behaviour measurement that is based on the video recordings under well-defined social context using animal models with variously social sensory interaction during development. The behaviour features digitized from the video recordings were visualised in a multivariate statistic space using principal component analysis. The clustering of the behaviour parameters suggested the existence of species- and stage-specific as well as cross-species behaviour modules. These modules were used to characterise the behaviour of children with or without autism spectrum disorders (ASDs). We found that socio-emotional behaviour is highly dependent on social context and the cross-species behaviour modules may predict neurobiological basis of ASDs.
- リンク情報
- ID情報
-
- DOI : 10.1038/srep02630
- ISSN : 2045-2322
- PubMed ID : 24022241
- Web of Science ID : WOS:000324157700001