論文

査読有り 国際誌
2020年6月2日

Artificial Construction of Immune Tissues/Organoids and Their Application for Immunological Intervention.

Current topics in microbiology and immunology
  • Yuka Kobayashi
  • ,
  • Takeshi Watanabe

記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1007/82_2020_215

Human-type lymphoid tissue organoids, which stably function in our body for a certain period of time or longer, may have a great potential as immune-stimulatory or immune-regulatory devices and could be utilized in the future for the treatment of various diseases such as cancer, severe infection, autoimmunity and congenital as well as acquired immunodeficiency resulting from severe infections or aging. In this review, we discuss about rationality and trials of the synthesis of immunologically functional lymphoid tissue organoids mainly in mouse. We have been recently trying to construct immunologically functioning human-type organoids, and the efforts are also briefly described.

リンク情報
DOI
https://doi.org/10.1007/82_2020_215
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/32483658
ID情報
  • DOI : 10.1007/82_2020_215
  • PubMed ID : 32483658

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