Yukari Sato - My portal

Profile Information

Affiliation: Antimicrobial Resistance Research Center, National Institute of Infectious Diseases

Degree: 博士（生命科学）(東北大)

J-GLOBAL ID: 201801003037901714
researchmap Member ID: B000311367

Research Interests

Research Areas

Research History

Apr, 2023 - Present

Antimicrobial Resistance Research Center, National Institute of Infectious Diseases
Apr, 2022 - Mar, 2023

博士研究員, 東北大学大学院生命科学研究科
Apr, 2017 - Mar, 2022

Assistant Professor, Graduate School of Life Sciences, Tohoku University
Mar, 2013 - Mar, 2017

Postdoctoral fellow, Institute of Materials Structure Science, High Energy Accelerator Research Organization
Apr, 2008 - Feb, 2013

Postdoctoral fellow, Japan biological informatics consortium
Apr, 2007 - Mar, 2008

Postdoctoral fellow, National Institute for Agro-Environmental Sciences

Education

Apr, 2001 - Mar, 2007

Graduate school of Life Sciences, Tohoku university
Apr, 1997 - Mar, 2001

Education, Miyagi university of Education

Awards

Mar, 2019

Murasaki Sendai Hagi Award (Tohoku University Award for Outstanding Women Researchers)

Yukari Sato

Papers

Structural and catalytic effects of surface loop-helix transplantation within haloalkane dehalogenase family.

Martin Marek, Radka Chaloupkova, Tatyana Prudnikova, Yukari Sato, Pavlina Rezacova, Yuji Nagata, Ivana Kuta Smatanova, Jiri Damborsky

Computational and structural biotechnology journal, 18 1352-1362, 2020 Peer-reviewed
Functional activity of the H3.3 histone chaperone complex HIRA requires trimerization of the HIRA subunit

Dominique Ray-Gallet, M. Daniel Ricketts, Yukari Sato, Kushol Gupta, Ekaterina Boyarchuk, Toshiya Senda, Ronen Marmorstein, Genevi{\`{e } }ve Almouzni

Nature Communications, 9(1), Aug, 2018 Peer-reviewed
Crystal structure of the nitrosuccinate lyase CreD in complex with fumarate provides insights into the catalytic mechanism for nitrous acid elimination

Yohei Katsuyama, Yukari Sato, Yoshinori Sugai, Yousuke Higashiyama, Miki Senda, Toshiya Senda, Yasuo Ohnishi

FEBS Journal, 285(8) 1540-1555, Apr 1, 2018 Peer-reviewed
Overcoming a hemihedral twinning problem in tetrahydrofolate-dependent O-demethylase crystals by the microseeding method

Ayaka Harada, Yukari Sato, Naofumi Kamimura, Nagarajan Venugopalan, Eiji Masai, Toshiya Senda

ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, 72(Pt12) 897-902, Dec, 2016 Peer-reviewed
Structural and functional analysis of a novel haloalkane dehalogenase with two halide-binding sites

Radka Chaloupkova, Tatyana Prudnikova, Pavlina Rezacova, Zbynek Prokop, Tana Koudelakova, Lukas Daniel, Jan Brezovsky, Wakako Ikeda-Ohtsubo, Yukari Sato, Michal Kuty …

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY, 70(7) 1884-1897, Jul, 2014 Peer-reviewed
Thirteen novel deoxynivalenol-degrading bacteria are classified within two genera with distinct degradation mechanisms

Ikuo Sato, Michihiro Ito, Masumi Ishizaka, Yoko Ikunaga, Yukari Sato, Shigenobu Yoshida, Motoo Koitabashi, Seiya Tsushima

FEMS MICROBIOLOGY LETTERS, 327(2) 110-117, Feb, 2012 Peer-reviewed
Stereoselectivity and conformational stability of haloalkane dehalogenase DbjA from Bradyrhizobium japonicum USDA110: the effect of pH and temperature

Radka Chaloupkova, Zbynek Prokop, Yukari Sato, Yuji Nagata, Jiri Damborsky

FEBS JOURNAL, 278(15) 2728-2738, Aug, 2011 Peer-reviewed
Enantioselectivity of Haloalkane Dehalogenases and its Modulation by Surface Loop Engineering

Zbynek Prokop, Yukari Sato, Jan Brezovsky, Tomas Mozga, Radka Chaloupkova, Tana Koudelakova, Petr Jerabek, Veronika Stepankova, Ryo Natsume, Jan G. E. van Leeuwen …

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 49(35) 6111-6115, 2010 Peer-reviewed
Crystallization and preliminary X-ray analysis of a novel haloalkane dehalogenase DbeA from Bradyrhizobium elkani USDA94

Tatyana Prudnikova, Tomas Mozga, Pavlina Rezacova, Radka Chaloupkova, Yukari Sato, Yuji Nagata, Jiri Brynda, Michal Kuty, Jiri Damborsky, Ivana Kuta Smatanova

ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS, 65(Pt4) 353-356, Apr, 2009 Peer-reviewed
Crystallization and preliminary crystallographic analysis of a haloalkane dehalogenase, DbjA, from Bradyrhizobium japonicum USDA110

Yukari Sato, Ryo Natsume, Masataka Tsuda, Jiri Damborsky, Yuji Nagata, Toshiya Senda

ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, 63(Pt4) 294-296, Apr, 2007 Peer-reviewed
Exogenous isolation of a plasmid involved in the degradation of gamma-Hexachlorocyclohexane from its contaminated soil.

Ryo Miyazaki, Yukari Sato, Michihiro Ito, Yoshiyuki Ohtsubo, Yuji Nagata, Masataka Tsuda

PLASMID, 57(2) 233-233, Mar, 2007
Complete nucleotide sequence of an exogenously isolated plasmid, pLB1, involved in gamma-hexachlorocyclohexane degradation

Ryo Miyazaki, Yukari Sato, Michihiro Ito, Yoshiyuki Ohtsubo, Yuji Nagata, Masataka Tsuda

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 72(11) 6923-6933, Nov, 2006 Peer-reviewed
Two rhizobial strains, Mesorhizobium loti MAFF303099 and Bradyrhizobium japonicum, USDA110, encode haloalkane dehalogenases with novel structures and substrate specificities

Y Sato, M Monincova, R Chaloupkova, Z Prokop, Y Ohtsubo, K Minamisawa, M Tsuda, J Damborsky, Y Nagata

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 71(8) 4372-4379, Aug, 2005 Peer-reviewed
Degradation of beta-hexachlorocyclohexane by haloalkane dehalogenase LinB from Sphingomonas paucimobilis UT26

Y Nagata, Z Prokop, Y Sato, P Jerabek, A Kumar, Y Ohtsubo, M Tsuda, J Damborsky

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 71(4) 2183-2185, Apr, 2005 Peer-reviewed

Misc.

Crystal Structure of the H3.3 Histone Chaperone Complex Subunit HIRA and its Functional Role

Yukari Sato, Toshiya Senda

Photon Factory Highlights 2018, 58-59, Oct, 2019 Invited
Sphingobium sp.SYK-6由来バニリン酸脱メチル酵素LigMの立体構造解析に向けた精製

原田彩佳, 佐藤優花里, 上村直史, 政井英司, 千田俊哉

日本生化学会大会(Web), 86th, 2013
Molecular Bases of Enantioselectivity of Haloalkane Dehalogenase DbjA

SATO Yukari, NATSUME Ryo, PROKOP Zbynek, BREZOVSKY Jan, CHALOUPKOVA Radka, DAMBORSKY Jiri, NAGATA Yuji, SENDA Toshiya

X-RAYS, 53(2) 124-129, 2011 Peer-reviewedInvited
Characterization of haloalkane dehalogenase from Rhizobia

Sato Yukari, Ikeda Wakako, Nagata Yuji, Minamisawa Kiwamu, Tsuda Masataka

15 201-201, 2003

Presentations

ハロアルカンデハロゲナーゼ及びデアミナーゼからなる融合酵素DahXのtRNA編集活性

高橋由紀子, 佐藤優花里, 中鉢千尋, 野々山翔太, 永田裕二

日本農芸化学会2021年度大会, Mar 20, 2021
Oligomeric states of MCE transporter components LinM and LinN from Sphingobium japonicum UT26

Yukari Sato, Takuya Ogata, Yuji Nagata

Jul, 2020
Bifunctional activity of a fusion enzyme DahX

Yukiko Takahashi, Chihiro Chubachi, Shouta Nonoyama, Yukari Sato, Yuji Nagata

Jul, 2020
二機能性融合タンパク質 DahX の tRNA 編集活性

高橋由紀子, 中鉢千尋, 野々山翔太, 佐藤優花里, 永田裕二

日本生化学会東北支部第86回例会・シンポジウム, May 30, 2020
有機塩素系殺虫剤分解細菌由来MCEトランスポーターの活性制御に関わるタンパク質間相互作用の解析

佐藤優花里, 尾形拓哉, 永田裕二

日本生化学会東北支部第86回例会・シンポジウム, May 30, 2020
tRNA editing activity of fusion enzyme DahX from Acidovora sp. KKS102

Mar 27, 2020
Biochemical analysis of a fusion protein DahX composed of two distinct enzymes

Jun 25, 2019
Sphingobium japonicum UT26株の有機塩素系殺虫剤分解に関わるABCトランスポーターの解析

尾形拓哉, 佐藤優花里, 永田裕二

日本生化学会東北支部第85回例会, Jun 8, 2019
ヒストンH3.3のヒストンシャペロンHIRA複合体の機能活性にはHIRAの三量体形成が必須である

佐藤優花里, 千田俊哉

日本生化学会東北支部第85回例会, Jun 8, 2019
有機塩素系殺虫剤の微生物分解に関わるMCE superfamilyタンパク質LinMはホモオリゴマー複合体を形成する

尾形拓哉, 中鉢千尋, 佐藤優花里, 大坪嘉行, 津田雅孝, 永田裕二

日本農芸化学会 2019年度大会, Mar 26, 2019
デアミナーゼ及びハロアルカンデハロゲナーゼドメインから成る新規融合タンパク質の酵素学的研究

佐藤優花里, 中鉢千尋, 大坪嘉行, 津田雅孝, 永田裕二

日本農芸化学会 2019年度大会, Mar 26, 2019
Crystal structure of the H3.3 histone chaperone complex subunit HIRA and its functional role

Yukari Sato,, Dominique Ray-Gallet, Daniel M Ricketts, Kushol Gupta, Ekaterina Boyarchuk, Ronen Marmostein, Genevieve Almouzni, Toshiya Senda

Asian Crystallographic Association 2018, Dec 3, 2018
ヒストンシャペロンHIRAは三量体を形成して機能する

佐藤優花里, 千田俊哉

第91回日本生化学会大会, Sep 24, 2018
ヒストンシャペロンHIRAの構造機能相関

佐藤優花里, 千田俊哉

第18回日本蛋白質科学会年会, Jun 27, 2018
デアミナーゼと融合した新規デハロゲナーゼの特徴

中鉢千尋, 佐藤優花里, 大坪嘉行, 津田雅孝, 永田裕二

日本農芸化学会 2018年度大会, Mar 17, 2018
二種類の酵素ドメインから構成される融合タンパク質の示差走査蛍光定量解析

佐藤優花里, 中鉢千尋, 永田裕二

第90回日本生化学会大会, Dec 6, 2017
ヒストンシャペロンHIRA C domainの立体構造解析

佐藤優花里, 千田俊哉

第89回日本生化学会大会, Sep 26, 2016
ヒストンシャペロンHIRA C domainの精製系の確立

佐藤優花里, 千田俊哉

第87回日本生化学会大会, 2014
ヒストンシャペロンHIRA C domainの精製系の確立

佐藤優花里, 千田俊哉

第87回日本生化学会大会, 2014
タンパク質の結晶化におけるシーディングの効果

佐藤優花里, 千田俊哉

第85回日本生化学会大会, 2012

Teaching Experience

Apr, 2020 - Mar, 2022

生命科学概論 (全学共通科目) (東北大学)

Professional Memberships

Social Activities

生命現象を原子スケールで理解する

Lecturer

東北大学男女共同参画推進センター, 研究者ってなに？「オープンキャンパス編」, Jul 31, 2019 - Jul 31, 2019