論文

2018年11月28日

[Anti-Hu antibody positive sensory neuronopathy causing painful legs and moving toes (PLMT) in a 75-year-old female with small cell lung cancer (SCLC)].

Rinsho shinkeigaku = Clinical neurology
  • Yuki Tsujimoto
  • ,
  • Akihito Hao
  • ,
  • Tatsuya Sato
  • ,
  • Takuto Hideyama
  • ,
  • Hideki Shibuya
  • ,
  • Yasushi Shiio

58
11
開始ページ
677
終了ページ
681
記述言語
日本語
掲載種別
研究論文(学術雑誌)
DOI
10.5692/clinicalneurol.cn-001198

The case is a 75-year-old female. She had dysesthesia in the distal extremities and truncal ataxia, and they had progressed in two months. Neurological examination revealed the findings of segmental dysesthesia in the distal extremities, impaired deep sensations in the trunk and four limbs, and painful legs and moving toes (PLMT). After workup, she was diagnosed with small cell lung cancer and her blood sample was positive for anti-Hu antibody. We concluded that her neurological symptoms were attributable to sensory neuronopathy associated with paraneoplastic syndrome. No cases with PLMT caused by paraneoplastic syndrome have been reported so far. She had chemotherapy to lung cancer and Duloxetine without improvement of PLMT. On the other hand, intravenous immunoglobulin treatment improved lightening pain in the toes without improvement of moving toes.

リンク情報
DOI
https://doi.org/10.5692/clinicalneurol.cn-001198
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/30369526
ID情報
  • DOI : 10.5692/clinicalneurol.cn-001198
  • PubMed ID : 30369526

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