Yuki Katanosaka

Profile Information

Affiliation: Kinjo Gakuin University

Degree: 理学博士(大阪大学)

Researcher number: 60432639
J-GLOBAL ID: 201801014309054503
researchmap Member ID: 7000024520

Research Interests

Research Areas

Research History

Apr, 2023 - Present

准教授, 金城学院大学薬学部
2023 - Mar, 2023

岡山大学大学院
Nov, 2019 - 2023

講師, 岡山大学医歯薬学総合研究科システム生理
Apr, 2006 - Oct, 2019

助教, システム生理, 岡山大学医歯薬学総合研究科
Apr, 2003 - Mar, 2006

日本学術振興会特別研究員 SPD, 国立循環器病センター研究所
Apr, 2000 - Mar, 2003

日本学術振興会特別研究員 PD, 科学技術特別研究員, 国立循環器病センター研究所
Apr, 1999 - Mar, 2000

流動研究員, 国立循環器病センター研究所

Education

- Mar, 1999

Osaka University

Papers

Reduced plasticity and microtubule densification in muscular dystrophy-related cardiomyopathy

Yuki Katanosaka

J Gen Physiol, 154(9) e2021esc45, Sep, 2022 InvitedLead authorLast authorCorresponding author
pathophysiological involvements of stretch-activated channels in pulmonary hypertension

Kazufumi Nakamura, Satoshi Akagi, Yuki Katanosaka

5(473) 63-65, May, 2022 Last author
Involvement of Transient Receptor Potential Vanilloid Channel 2 in the Induction of Lubricin and Suppression of Ectopic Endochondral Ossification in Mouse Articular Cartilage.

Hideki Nakamoto, Yuki Katanosaka, Ryota Chijimatsu, Daisuke Mori, Fengjun Xuan, Fumiko Yano, Yasunori Omata, Yuji Maenohara, Yasutaka Murahashi, Kohei Kawaguchi …

Arthritis & rheumatology (Hoboken, N.J.), 73(8) 1441-1450, Aug, 2021 Peer-reviewed
Elimination of fukutin reveals cellular and molecular pathomechanisms in muscular dystrophy-associated heart failure.

Yoshihiro Ujihara, Motoi Kanagawa, Satoshi Mohri, Satomi Takatsu, Kazuhiro Kobayashi, Tatsushi Toda, Keiji Naruse, Yuki Katanosaka

Nature communications, 10(1) 5754-5754, Dec 17, 2019 Peer-reviewedLast authorCorresponding author
TRPV2 is required for mechanical nociception and the stretch-evoked response of primary sensory neurons.

Katanosaka K, Takatsu S, Mizumura K, Naruse K, Katanosaka Y

Scientific reports, 8(1) 16782, Nov, 2018 Peer-reviewedLast author
Effects of induced Na+/Ca2+ exchanger overexpression on the spatial distribution of L-type Ca2+ channels and junctophilin-2 in pressure-overloaded hearts

Yoshihiro Ujihara, Satoshi Mohri, Yuki Katanosaka

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 480(4) 564-569, Nov, 2016 Peer-reviewedLast authorCorresponding author
Induced NCX1 overexpression attenuates pressure overload-induced pathological cardiac remodelling

Yoshihiro Ujihara, Keiichiro Iwasaki, Satomi Takatsu, Ken Hashimoto, Keiji Naruse, Satoshi Mohri, Yuki Katanosaka

CARDIOVASCULAR RESEARCH, 111(4) 348-361, Sep, 2016 Peer-reviewedLast authorCorresponding author
Involvement of S1P1 receptor pathway in angiogenic effects of a novel adenosine-like nucleic acid analog COA-Cl in cultured human vascular endothelial cells

Junsuke Igarashi, Takeshi Hashimoto, Yasuo Kubota, Kazuyo Shoji, Tokumi Maruyama, Norikazu Sakakibara, Yoh Takuwa, Yoshihiro Ujihara, Yuki Katanosaka, Satoshi Mohri …

Pharmacology Research and Perspectives, 2(5) e00068, Oct 1, 2014 Peer-reviewed
Overexpression of LARGE suppresses muscle regeneration via down-regulation of insulin-like growth factor 1 and aggravates muscular dystrophy in mice

Fumiaki Saito, Motoi Kanagawa, Miki Ikeda, Hiroki Hagiwara, Toshihiro Masaki, Hidehiko Ohkuma, Yuki Katanosaka, Teruo Shimizu, Masahiro Sonoo, Tatsushi Toda …

HUMAN MOLECULAR GENETICS, 23(17) 4543-4558, Sep, 2014 Peer-reviewed
TRPV2 is critical for the maintenance of cardiac structure and function in mice

Yuki Katanosaka, Keiichiro Iwasaki, Yoshihiro Ujihara, Satomi Takatsu, Koki Nishitsuji, Motoi Kanagawa, Atsushi Sudo, Tatsushi Toda, Kimiaki Katanosaka, Satoshi Mohri …

NATURE COMMUNICATIONS, 5 3932, May, 2014 Peer-reviewedLead authorCorresponding author
Impaired viability of muscle precursor cells in muscular dystrophy with glycosylation defects and amelioration of its severe phenotype by limited gene expression

Motoi Kanagawa, Chih-Chieh Yu, Chiyomi Ito, So-ichiro Fukada, Masako Hozoji-Inada, Tomoko Chiyo, Atsushi Kuga, Megumi Matsuo, Kanoko Sato, Masahiko Yamaguchi …

HUMAN MOLECULAR GENETICS, 22(15) 3003-3015, Aug, 2013 Peer-reviewed
Mechanical Stretch Increases the Proliferation While Inhibiting the Osteogenic Differentiation in Dental Pulp Stem Cells

Masaki Hata, Keiko Naruse, Shogo Ozawa, Yasuko Kobayashi, Nobuhisa Nakamura, Norinaga Kojima, Maiko Omi, Yuki Katanosaka, Toru Nishikawa, Keiji Naruse …

TISSUE ENGINEERING PART A, 19(5-6) 625-633, Mar, 2013 Peer-reviewed
[Musculoskeletal rehabilitation and bone. A novel approach to mechanotransduction using cell-adhesion-patterned cells].

Katanosaka Y, Naruse K

Clinical calcium, 20(4) 514-519, Apr, 2010 Peer-reviewedLead authorCorresponding author
A Rapid Microfluidic Switching System for Analysis at the Single Cellular Level

Akira Yamada, Yuki Katanosaka, Satoshi Mohri, Keiji Naruse

IEEE TRANSACTIONS ON NANOBIOSCIENCE, 8(4) 306-311, Dec, 2009 Peer-reviewed
Dominant-negative inhibition of Ca2+ influx via TRPV2 ameliorates muscular dystrophy in animal models

Yuko Iwata, Yuki Katanosaka, Yuji Arai, Munekazu Shigekawa, Shigeo Wakabayashi

HUMAN MOLECULAR GENETICS, 18(5) 824-834, Mar, 2009 Peer-reviewed
Impairment of leukocyte deformability in patients undergoing esophagectomy

Tomohiko Suemori, Hiroshi Morimatsu, Satoshi Mizobuchi, Kiyoshi Morita, Yuki Katanosaka, Satoshi Mohri, Keiji Naruse

CLINICAL HEMORHEOLOGY AND MICROCIRCULATION, 41(2) 127-136, 2009 Peer-reviewed
Analysis of cyclic-stretching responses using cell-adhesion-patterned cells

Yuki Katanosaka, Jin-Hua Bao, Tomoyo Komatsu, Tomohiko Suemori, Akira Yamada, Satoshi Mohri, Keiji Naruse

JOURNAL OF BIOTECHNOLOGY, 133(1) 82-89, Jan, 2008 Peer-reviewedLead author
Enhanced Na+/H+ exchange activity contributes to the pathogenesis of muscular dystrophy via involvement of p2 receptors

Yuko Iwata, Yuki Katanosaka, Takashi Hisamitsu, Shigeo Wakabayashi

AMERICAN JOURNAL OF PATHOLOGY, 171(5) 1576-1587, Nov, 2007 Peer-reviewed
Heart slice NMR

Tadayuki Uetani, Daisuke Yamashita, Juichiro Shimizu, Hiromi Misawa, Yasushi Tatematsu, Yukihisa Hamaguchi, Takehiro Miyasaka, Yuki Katanosaka, Toshiaki Kato, Tatsuaki Matsubara …

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 292(2) H1181-H1186, Feb, 2007 Peer-reviewed
Regulation of the cardiac Na+/Ca2+ exchanger by calcineurin and protein kinase C

Munekazu Shigekawa, Yuki Katanosaka, Shigeo Wakabayashi

SODIUM-CALCIUM EXCHANGE AND THE PLASMA MEMBRANE CA2+-ATPASE IN CELL FUNCTION: FIFTH INTERNATIONAL CONFERENCE, 1099 53-63, 2007 Peer-reviewed

Misc.

TRPV2 IS INVOLVED IN SYNCYTIALIZATION OF HUMAN AND MOUSE TROPHOBLAST.

Katrien De Clercq, Vicente Perez-Garcia, Jorge Lopez-Tello, Yuki Katanosaka, Thomas Voets, Amanda N. Sferruzzi-Perri, Joris Vriens

PLACENTA, 112 E80-E80, Sep, 2021
STRAIN-SPECIFIC ADAPTATIONS IN PLACENTAL TRANSPORT FUNCTION OPTIMISE FETAL OUTCOMES IN MICE LACKING TRPV2

Katrien De Clercq, Jorge Lopez-Tello, Yuki Katanosaka, Thomas Voets, Amanda N. Sferruzzi-Perri, Joris Vriens

PLACENTA, 112 E20-E20, Sep, 2021
Abnormal structure of Golgi-microtubule network in muscular dystrophy-associated heart failure

Yuki Katanosaka

278(3) 231-232, 2021 InvitedLead authorCorresponding author
Mice Lacking TRPV2 Adopt Compensatory Mechanism to Comply with Fetal Needs.

Katrien De Clercq, Jorge Lopez-Tello, Yuki Katanosaka, Thomas Voets, Amanda N. Sferruzzi-Perri, Joris Vriens

REPRODUCTIVE SCIENCES, 27(SUPPL 1) 250A-250A, Mar, 2020
TRPV2 is Crucial for the Development of Intercalated Discs in Mouse Hearts

Yuki Katanosaka, Makoto Shibuya, Yoshihiro Ujihara, Satoshi Mohri, Keiji Naruse

BIOPHYSICAL JOURNAL, 116(3) 538A-538A, Feb, 2019
TRPV2 is Crucial for the Development of Excitation-Contraction Coupling in Neonatal Cardiomyocytes

Yuki Katanosaka, Yoshihiro Ujihara, Yumiko Chiba, Satoshi Mohri, Keiji Naruse

BIOPHYSICAL JOURNAL, 114(3) 484A-484A, Feb, 2018
The Role of NCX1 on the Maintenance of T-Tubule Architecture in Pressure-Overloaded Hearts

Yoshihiro Ujihara, Satomi Takatsu, Keiji Naruse, Satoshi Mohri, Yuki Katanosaka

BIOPHYSICAL JOURNAL, 114(3) 619A-619A, Feb, 2018
The role of TRPV2 in the hearts

Yuki Katanosaka

JOURNAL OF PHARMACOLOGICAL SCIENCES, 133(3) S44-S44, Mar, 2017
1D42 Mechanical signaling via TRPV2 in cardiomyocytes

UJIHARA Yoshihiro, HASHIMOTO Ken, MOHRI Satoshi, KATANOSAKA Yuki

2016(28) "1D42-1"-"1D42-4", Jan 9, 2016
TRPV2 is crucial for cardiac structure and function

Yuki Katanosaka

JOURNAL OF PHARMACOLOGICAL SCIENCES, 128(3) S23-S23, Jul, 2015
LARGEの過剰発現はIGF‐1の発現低下により筋再生を抑制してマウスの筋ジストロフィーを悪化させる

斉藤史明, 金川基, 池田美樹, 萩原宏毅, 真先敏弘, 大熊秀彦, 片野坂友紀, 清水輝夫, 園生雅弘, 戸田達史 …

日本生化学会大会(Web), 87th 4P-409 (WEB ONLY)-409], Oct, 2014
0820 Cell stimulation and response analysis using microfluidics

YAMADA Akira, KATANOSAKA Yuki, MOHRI Satoshi, NARUSE Keiji

2009(22) 315-315, Jan 8, 2010
0234 Mechanosensor in Cardiovascular System

2009(22) 218-218, Jan 8, 2010
Stretch-induced Up-regulation of Caveolae Formation and SOC Activities in HUVEC

Yuki Katanosaka, Keiji Naruse

BIOPHYSICAL JOURNAL, 96(3) 268A-268A, Feb, 2009
揺動培養によるマウス胚盤胞到達率の上昇

黒田ユカ, 松浦宏治, 片野坂友紀, 毛利聡, 舟橋弘晃, 成瀬恵治

日本生体医工学会大会プログラム・論文集(CD-ROM), 47th, 2008
Tolerance of the developing cyanotic heart to ischemia-reperfusion injury: Impact of hypoxia from birth

Yasuhiro Fujii, Kozo Ishino, Tomoko Tomii, Yasuhiro Kotani, Yoshinori Miyahara, Shingo Kasahara, Shunji Sano, Teiji Akag, Yuki Katanosaka, Satoru Mori

INTERNATIONAL JOURNAL OF CARDIOLOGY, 122 47-47, Dec, 2007
岡山大学大学院医歯薬学総合研究科生体機能制御科学専攻・機能制御学システム循環生理学教室(研究室・研究施設紹介)

毛利聡, 片野坂友紀, 入部玄太郎, 成瀬恵治

生体医工学 : 日本エム・イー学会誌, 45(3) 227-228, Sep 10, 2007

Presentations

The role of TRPV2 in pressure overload-induced pathological cardiac remodeling

9th world congress of biomechanics, Jul 14, 2022 Invited
TRPV2 is essential for the maturation and hypertrophic responses of cardiomyocytes via promotion of sarcoplasmic reticulum Ca2+ ATPase (SERCA) expression

9th world congress of biomechanics, Jul 13, 2022
細径線維受容器終末のTRPV2チャネルを介した機械痛覚の末梢神経機構

田口徹, 片野坂友紀, 太田大樹, 片野坂公明

日本基礎理学療法学会, Oct 23, 2021
Analysis of Molecular Mechanisms Involved in Mechanical Adaptation: In the Case of Repeated Bout Effect on the Exercise-induced Muscle Pain.

The 3rd International Yangtze River Delta Symposium on Mechanobiology & the 9th Chinese National Symposium of Medical Biophysics, Oct 16, 2021
TRPV2 is Involved in the Hypertrophic Response of Skeletal Muscle Induced by Mechanical Overload

The 3rd International Yangtze River Delta Symposium on Mechanobiology & the 9th Chinese National Symposium of Medical Biophysics, Oct 16, 2021
The Role of TRPV2 in cardiovascular systems

Yuki Katanosaka

Sep 16, 2021 Invited
TRPA1 contributes to lengthening contraction-induced muscular mechanical hyperalgesia

Sep 15, 2021
ダイナミン1は微小管の配向を調節しTRPV2の細胞膜移行を制御する

籔彩夏, 安岡宏樹, 片野坂友紀, 阿部匡史, 竹田哲也, 竹居孝二, 山田浩司

生化学会中四国支部会, Sep 10, 2021
Involvement of TRPA1 but not TRPV2 in rodent models of lengthening contraction-induced muscular mechanical hyperalgesia

Hiroki Ota, Leo Washizawa, Kohei Hayashi, Yuki Katanosaka, Kimiaki Kaanosaka, Makoto Tominaga, Toru Taguchi, Kazue Mizumura

日本神経科学会大会, Jul 28, 2021
The role of TRPV2 in cardiac physiology and cardiovascular disease

Yuki Katanosaka

Jun 16, 2021 Invited
The role of TRPV2 on physiological and pathological remodeling of myocytes

Yuki Katanosaka

Mar, 2021 Invited
TRPV2 Promotes Hypoxia-induced Pulmonary Hypertension

Kazufumi Nakamura, Yuki Katanosaka, Satoshi Akagi, Yukihiro Saito, Kentaro Ejiri, Toru Miyoshi, Masashi Yoshida, Satoshi Hirohata, Hiroshi Ito

2021
マウス遅発性筋痛モデルにおけるTRPチャネルの関与

太田大樹, 片野坂公明, 村瀬詩織, 加塩麻紀子, 富永真琴, 片野坂友紀, 田口徹, 水村和枝

第25回日本基礎理学療法学術大会, Dec 12, 2020
遅発性筋痛の分子機構： TRPA1およびTRPV2ノックアウトマウスを用いた解析

太田大樹, 片野坂公明, 村瀬詩織, 加塩麻紀子, 富永真琴, 片野坂友紀, 田口徹, 水村和枝

第42回日本疼痛学会, Dec 4, 2020
Involvement of TRPV2 in cutaneous mechanical nociception: Electrophysiological analysis using single-fiber recording

Dec 4, 2020
The role of TRPV2 on the maintenance of cardiac contractile function

Yuki Katanosaka

Dec, 2020
マウス遅発性筋痛モデルにおける機械感受性TRPチャネルの関与

太田大樹, 片野坂公明, 村瀬詩織, 加塩麻紀子, 富永真琴, 片野坂友紀, 田口徹, 水村和枝

第13回日本運動器疼痛学会, Nov 28, 2020
圧負荷によって引き起こされる心不全における心血管TRPV2の役割

片野坂友紀

日本脈管学会総会シンポジウム, Nov, 2020 Invited
Decreased mechanical response of cutaneous nociceptors in TRPV2-deficient mice

Toru Taguchi, Yuki Katanosaka, Kimiaki Katanosaka

Jul 29, 2020
The molecular mechanism of cardiac mechanical response in physiology and pathophysiology

Yuki Katanosaka

Jun, 2020 Invited

Teaching Experience

Professional Memberships

Research Projects

Resilience Biology -What are the molecular mechanisms that support the resilience of life?-

Grants-in-Aid for Scientific Research, Grant-in-Aid for Transformative Research Areas (B), Japan Society for the Promotion of Science, Apr, 2023 - Mar, 2026
筋血管のメカニカルストレス応答の解明に基づく運動後の筋痛発症と適応機序の理解

科学研究費助成事業基盤研究(C), 基盤研究(C), 日本学術振興会, Apr, 2022 - Mar, 2025

片野坂公明, 片野坂友紀
新規メカニカル負荷装置の開発を通した次世代メカノメディスンへの挑戦

科学研究費助成事業基盤研究(A), 基盤研究(A), 日本学術振興会, Apr, 2021 - Mar, 2024

成瀬恵治, 西山雅祥, 高橋賢, 片野坂友紀, 森松賢順, 入部玄太郎
大動脈解離におけるメカノバイオロジー機構の解明

科学研究費助成事業基盤研究(C), 基盤研究(C), 日本学術振興会, Apr, 2021 - Mar, 2024

三好亨, 中村一文, 米澤朋子, 片野坂友紀
心血管メカノセンサーTRPV2の低酸素誘発性肺高血圧症への関与解明と治療法開発

科学研究費助成事業基盤研究(C), 基盤研究(C), 日本学術振興会, Apr, 2021 - Mar, 2024

中村一文, 鵜殿平一郎, 片野坂友紀, 赤木達
Monitoring of the activity of cardiac mechanosensor

Grants-in-Aid for Scientific Research Grant-in-Aid for Challenging Research (Pioneering), Grant-in-Aid for Challenging Research (Pioneering), Japan Society for the Promotion of Science, Jul, 2020 - Mar, 2024
The role of mechanically-sensitive ion channels in delayed onset muscle soreness

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2020 - Mar, 2023
Elucidation of the mechanisms underlying muscle adaptation to exercise via neuromuscular crosstalk based on biomedical engineering analysis.

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B), Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2018 - Mar, 2022

Katanosaka Kimiaki
Role of TRPV2 in podocytes

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2019 - Mar, 2021
Understanding of the mechanism of ribitol-phosphate modification and application of its physiological function to therapy

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B), Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2018 - Mar, 2021

Kanagawa Motoi
Identification of mechanical signal from intercalated discs

Grants-in-Aid for Scientific Research Grant-in-Aid for Challenging Research (Exploratory), Grant-in-Aid for Challenging Research (Exploratory), Japan Society for the Promotion of Science, Jun, 2018 - Mar, 2020

Katanosaka Yuki
Mechanotransduction on cardiac physiology

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B), Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2017 - Mar, 2020

KATANOSAKA YUKI
生体の機械受容機構の分子基盤と生理的意義の解明による革新的医療ターゲットの確立

革新的先端研究開発支援事業, AMED, Dec, 2015 - Mar, 2019

片野坂友紀
Biomedical engineering-based analysis of the molecular mechanisms underlying functional crosstalk between muscle and neurons.

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B), Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2015 - Mar, 2018

KATANOSAKA Kimiaki, HIBINO Yuhei, SHIMIZU Rie
Elucidation of structure, modification mechanism, pathophysiological roles of a novel posttranslational modification, post-phosphoryl sugar chain

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B), Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2015 - Mar, 2018

Kanagawa Motoi
Establishment of the way to identify and isolate the heat-sensitive primary sensory neurons for understanding the peripheral mechanisms of heat pain.

Grants-in-Aid for Scientific Research Grant-in-Aid for Challenging Exploratory Research, Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, Apr, 2015 - Mar, 2017

KATANOSAKA Kimiaki, HIBINO Yuhei, SHIMIZU Rie
Information control for a linkage between macro cardiac function and gene expression: physiomic analysis of responses to oxygen environment

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B), Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2014 - Mar, 2017

Mohri Satoshi
The importance of local Ca2+ control beneathe the T-tubule membrane in cardiomyocytes

Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (A), Grant-in-Aid for Young Scientists (A), Japan Society for the Promotion of Science, Apr, 2014 - Mar, 2017

Ujihara Yoshihiro, MOHRI Satoshi, HASHIMOTO Ken, HANASHIMA Akira, KATANOSAKA Yuki, HONDA Takeshi
Elucidation of molecular mechanism of mechanotransduction in the heart

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B), Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2014 - Mar, 2017

Katanosaka Yuki
The maintenance of cardiac structure and function by mechanical feedback system involving multiple organ systems.

Grants-in-Aid for Scientific Research Grant-in-Aid for Challenging Exploratory Research, Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, Apr, 2014 - Mar, 2016

Katanosaka Yuki, UJIHARA Yoshihiro, MOHRI Satoshi, KATANOSAKA Kimiaki

Profile Information

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Papers

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Presentations

Teaching Experience

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