This paper considers Smith predictor-based compensation for the dead-time of pneumatic vibration isolators. In the implementation of the predictor, the plant modeling and the dead-time measurement are needed. To improve the model accuracy, the approximation model of pipe resonance is developed. Moreover, to tune parameters of the plant model efficiently, the number of parameters is reduced. The time delay in the Smith predictor is determined by considering the frequency resonance of the control system for vibration isolators. Experimental results demonstrate the effectiveness of our implementation methods. © 2013 IEEE.