yukinori hirano - My portal - researchmap

Profile Information

Affiliation: Assistant Professor, The Hong Kong University of Science and Technology

Degree: 理学博士(名古屋大学)

J-GLOBAL ID: 201201003232656410
researchmap Member ID: B000222425

External link: https://yukinori7676.wixsite.com/website

クロマチン上で起きるエピジェネティクス、そしてエピジェネティクスが支配する遺伝子発現、これらが脳の高次機能とどのように関わるかに焦点をあて、研究を遂行していきます。

Research Interests

4

Research Areas

1

Life sciences / Neuroscience - general / learning and memory

Research History

3

Apr, 2012 - Present

researcher, Tokyo Metropolitan Institute of Medical Science
Apr, 2009 - Mar, 2012

researcher, Tokyo Metropolitan Institute of Medical Science
特定准教授, 京都大学医学研究科

Education

2

Apr, 2005 - Mar, 2008

Nagoya University
Apr, 2003 - Mar, 2005

Nagoya University

Papers

15

Binding of Multiple Rap1 Proteins Stimulates Chromosome Breakage Induction during DNA Replication

Greicy H. Goto, Sevil Zencir, Yukinori Hirano, Hiroo Ogi, Andreas Ivessa, Katsunori Sugimoto

PLOS GENETICS, 11(8), Aug, 2015 Peer-reviewed
Glial dysfunction causes age-related memory impairment in Drosophila.

Daisuke Yamazaki, Junjiro Horiuchi, Kohei Ueno, Taro Ueno, Shinjiro Saeki, Motomi Matsuno, Shintaro Naganos, Tomoyuki Miyashita, Yukinori Hirano, Hiroyuki Nishikawa …

Neuron, 84(4) 753-763, Nov, 2014 Peer-reviewed
[Hunger-driven modulation in brain functions].

Hirano Y, Saitoe M

Brain and nerve = Shinkei kenkyu no shinpo, 66(1) 41-48, Jan, 2014 Peer-reviewed
Hunger and memory; CRTC coordinates long-term memory with the physiological state, hunger.

Hirano Y, Saitoe M

Communicative & integrative biology, 6(5) e25152, Sep, 2013 Peer-reviewed
Age-relatedmemory impairment in Drosophila

Minoru Saitoe, Shinjiro Saeki, Yukinori Hirano, Junjiro Horiuchi

Behavioral Genetics of the Fly (Drosophila Melanogaster), 177-182, Jan 1, 2013 Peer-reviewed
Long-term enhancement of synaptic transmission between antennal lobe and mushroom body in cultured Drosophila brain.

Ueno K, Naganos S, Hirano Y, Horiuchi J, Saitoe M

The Journal of physiology, 591(1) 287-302, Jan, 2013 Peer-reviewed
Fasting launches CRTC to facilitate long-term memory formation in Drosophila.

Yukinori Hirano, Tomoko Masuda, Shintaro Naganos, Motomi Matsuno, Kohei Ueno, Tomoyuki Miyashita, Junjiro Horiuchi, Minoru Saitoe

Science, 339(6118) 443-446, Jan, 2013 Peer-reviewed
Reactive oxygen species are not involved in the onset of age-related memory impairment in Drosophila

Y. Hirano, Y. Kuriyama, T. Miyashita, J. Horiuchi, M. Saitoe

GENES BRAIN AND BEHAVIOR, 11(1) 79-86, Feb, 2012 Peer-reviewed
Subtelomere-binding protein Tbf1 and telomere-binding protein Rap1 collaborate to inhibit localization of the Mre11 complex to DNA ends in budding yeast

Kenzo Fukunaga, Yukinori Hirano, Katsunori Sugimoto

MOLECULAR BIOLOGY OF THE CELL, 23(2) 347-359, Jan, 2012 Peer-reviewed
Rif1 and Rif2 Inhibit Localization of Tel1 to DNA Ends

Yukinori Hirano, Kenzo Fukunaga, Katsunori Sugimoto

MOLECULAR CELL, 33(3) 312-322, Feb, 2009 Peer-reviewed
Role of budding yeast Rad18 in repair of HO-induced double-strand breaks

Yukinori Hirano, Jayant Reddy, Katsunori Sugimoto

DNA REPAIR, 8(1) 51-59, Jan, 2009 Peer-reviewed
Cdc13 telomere capping decreases Mec1 association but does not affect Tel1 association with DNA ends

Yukinori Hirano, Katsunori Sugimoto

MOLECULAR BIOLOGY OF THE CELL, 18(6) 2026-2036, Jun, 2007 Peer-reviewed
ATR homolog Mec1 controls association of DNA polymerase zeta-Rev1 complex with regions near a double-strand break

Y Hirano, K Sugimoto

CURRENT BIOLOGY, 16(6) 586-590, Mar, 2006 Peer-reviewed
Role of the C terminus of Mec1 checkpoint kinase in its localization to sites of DNA damage

D Nakada, Y Hirano, Y Tanaka, K Sugimoto

MOLECULAR BIOLOGY OF THE CELL, 16(11) 5227-5235, Nov, 2005 Peer-reviewed
Requirement of the Mre11 complex and exonuclease 1 for activation of the Mec1 signaling pathway

D Nakada, Y Hirano, K Sugimoto

MOLECULAR AND CELLULAR BIOLOGY, 24(22) 10016-10025, Nov, 2004 Peer-reviewed

Misc.

3

Decoding epigenetics related to distinct phases of long-term memory in Drosophila

Yukinori Hirano

GENES & GENETIC SYSTEMS, 91(6) 330-330, Dec, 2016
Shifting transcriptional machinery is required for long-term memory maintenance and modification in Drosophila mushroom bodies.

Hirano Y, Ihara K, Masuda T, Yamamoto T, Iwata I, Takahashi A, Awata H, Nakamura N, Takakura M, Suzuki Y …

Nat Commun., 7 13471, Nov 14, 2016 Peer-reviewed
Maintenance of long-term memory requires persistent regulation of gene expression

Yukinori Hirano, Minoru Saitoe

NEUROSCIENCE RESEARCH, 71 E90-E90, 2011

Presentations

2

Maintenance of long-term memory requires persistent regulation of gene expression

yukinori hirano

Dec, 2011
長期記憶の保持には持続的な遺伝子発現制御が必須である

平野恭敬

第３４回日本神経科学大会, Sep, 2011

Research Projects

9

コンパートメント特異的なシナプスプロテオミクス解析法の確立

科学研究費助成事業, 基盤研究(B), 日本学術振興会, Apr, 2020 - Mar, 2023

平野恭敬, 中川れい子
老化個性の可視化を通した、老化プロセス多様性の解明

科学研究費助成事業, 挑戦的研究(萌芽), 日本学術振興会, Jul, 2020 - Mar, 2021

平野恭敬
The study of memory consolidation through the parallel circuit in Drosophila mushroom body

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area), Japan Society for the Promotion of Science, Apr, 2018 - Mar, 2020
Development of the anterograde neural tracing system for understanding the neural circuit for memory

Grants-in-Aid for Scientific Research, Grant-in-Aid for Young Scientists (A), Japan Society for the Promotion of Science, Apr, 2017 - Mar, 2020

Hirano Yukinori
記憶の固定化、および書き換えに寄与する新規予測誤差神経の探求

科学研究費助成事業, 新学術領域研究(研究領域提案型), 日本学術振興会, Apr, 2016 - Mar, 2018

平野恭敬
長期記憶の不安定化を司る分子メカニズムと神経基盤の解明

科学研究費助成事業, 新学術領域研究(研究領域提案型), 日本学術振興会, Apr, 2014 - Mar, 2016

平野恭敬
Glial dysfunction causes age-related memory impairment in Drosophila

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (A), Japan Society for the Promotion of Science, Apr, 2013 - Mar, 2016

SAITOE Minoru, MIYASHITA Tomoyuki, UENO Kohei, MATSUNO Motomi, HIRANO Yukinori, NAGANOS Shintaro
Study of the molecular mechanisms in which mild fasting facilitates memory

Grants-in-Aid for Scientific Research, Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, Apr, 2013 - Mar, 2015

HIRANO yukinori
記憶タグとして機能するエピジェネティクスの解明

戦略的創造研究推進事業・さきがけ, 科学技術振興機構, Oct, 2011 - Mar, 2015

平野恭敬