論文

査読有り 筆頭著者 責任著者 国際誌
2022年

The claw sign predicts first-pass effect in mechanical thrombectomy for cerebral large vessel occlusion in the anterior circulation.

Surgical neurology international
  • Yuki Yamamoto
  • ,
  • Nobuaki Yamamoto
  • ,
  • Yasuhisa Kanematsu
  • ,
  • Izumi Yamaguchi
  • ,
  • Manabu Ishihara
  • ,
  • Takeshi Miyamoto
  • ,
  • Shu Sogabe
  • ,
  • Kenji Shimada
  • ,
  • Yasushi Takagi
  • ,
  • Yuishin Izumi

13
開始ページ
72
終了ページ
72
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.25259/SNI_1160_2021

Background: Mechanical thrombectomy (MT) is an effective treatment for acute cerebral large vessel occlusion (LVO). Complete recanalization of vessels in a single procedure is defined as the first-pass effect (FPE) and is associated with good prognosis. In this study, angiographic clot protruding sign termed the "claw sign," was examined as candidate preoperative imaging factor for predicting the FPE. Methods: We retrospectively analyzed data from 91 consecutive patients treated for acute LVO in the anterior circulation by MT between January 2014 and December 2019. The claw sign was defined as a thrombus that protruded proximally by more than half of the diameter of the parent artery. Radiological findings such as claw sign, clinical and etiological features, and outcomes were compared between groups with and without successful FPE. Multivariate analysis was conducted to evaluate perioperative factors associated with FPE. Results: FPE was achieved in 26 of 91 (28.6%) patients and the claw sign was observed in 34 of 91 (37.4%) patients. The claw sign was significantly more frequent in the successful FPE group than in the failed FPE group (53.8% vs. 30.8%; P = 0.040). After the multivariate analysis, the claw sign was the only pretreatment parameter that could predict FPE (odds ratio, 2.67; 95% confidence interval, 1.01-7.06; P = 0.047). Conclusion: The claw sign is an angiographic imaging factor that might predict FPE after MT for anterior circulation acute ischemic stroke.

リンク情報
DOI
https://doi.org/10.25259/SNI_1160_2021
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/35242438
PubMed Central
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8888293
ID情報
  • DOI : 10.25259/SNI_1160_2021
  • PubMed ID : 35242438
  • PubMed Central 記事ID : PMC8888293

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