論文

国際誌
2020年10月13日

Validation of the Japanese version of the Lupus Damage Index Questionnaire in a large observational cohort: A two-year prospective study.

Modern rheumatology
  • Yuko Okamoto
  • ,
  • Yasuhiro Katsumata
  • ,
  • Sayumi Baba
  • ,
  • Yasushi Kawaguchi
  • ,
  • Masayoshi Harigai

開始ページ
1
終了ページ
9
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1080/14397595.2020.1829341

OBJECTIVES: The Lupus Damage Index Questionnaire (LDIQ) is a validated patient-reported outcome measure to assess accumulated damage in systemic lupus erythematosus (SLE). We aimed to translate it into Japanese and further investigate its validity and reliability. METHODS: The English version of the LDIQ was translated into Japanese and administered to Japanese patients with SLE (n = 259) at our university clinic. Physicians simultaneously completed the Systemic Lupus International Collaborating Clinics Damage Index (SDI) and SLE Disease Activity Index 2000 (SLEDAI-2K). Patients were prospectively followed for a repeat assessment the following year. RESULTS: The median LDIQ score was 2.0. The LDIQ demonstrated substantial correlation with the SDI but poor correlation with the SLEDAI-2K (Spearman's ρ = 0.75 and -0.08, respectively). These results suggested its convergent and discriminant validity. The LDIQ demonstrated good test-retest reliability (intraclass correlation coefficient = 0.85). When the effect size and standardized response mean for the LDIQ were assessed only in patients who had a change ≥1 in the SDI, they demonstrated a small to moderate responsiveness: 0.43 and 0.59, respectively. CONCLUSION: The Japanese version of the LDIQ had acceptable reliability and validity and its performance was comparable with the original version.

リンク情報
DOI
https://doi.org/10.1080/14397595.2020.1829341
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/32990111
ID情報
  • DOI : 10.1080/14397595.2020.1829341
  • PubMed ID : 32990111

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