2020年1月23日
The optimization of cancer photodynamic therapy by utilization of a pi-extended porphyrin-type photosensitizer in combination with MITO-Porter.
Chemical communications (Cambridge, England)
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- 巻
- 56
- 号
- 7
- 開始ページ
- 1145
- 終了ページ
- 1148
- 記述言語
- 英語
- 掲載種別
- DOI
- 10.1039/c9cc08563g
The uncontrolled production of reactive oxygen species during photodynamic therapy (PDT) induces oxidative stress. The full potential of PDT is accomplished by delivery of a pi-extended porphyrin-type photosensitizer into mitochondria of tumor cells using a MITO-Porter, a mitochondrial targeting nanodevice. This strategy can be implemented for innovative cancer therapy.
- ID情報
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- DOI : 10.1039/c9cc08563g
- PubMed ID : 31895356