伊東祐美 (Yumi Itoh) - マイポータル

基本情報

所属: 順天堂大学微生物学助教

J-GLOBAL ID: 202001015578057823
researchmap会員ID: R000003065

研究キーワード

研究分野

ライフサイエンス / ウイルス学 /

論文

Importin-7-dependent nuclear translocation of the Flavivirus core protein is required for infectious virus production.

Yumi Itoh, Yoichi Miyamoto, Makoto Tokunaga, Tatsuya Suzuki, Akira Takada, Akinori Ninomiya, Tomomi Hishinuma, Mami Matsuda, Yoshihiro Yoneda, Masahiro Oka …

PLoS pathogens 20(8) e1012409 2024年8月
An inhaled ACE2 decoy confers protection against SARS-CoV-2 infection in preclinical models.

Emiko Urano, Yumi Itoh, Tatsuya Suzuki, Takanori Sasaki, Jun-Ichi Kishikawa, Kanako Akamatsu, Yusuke Higuchi, Yusuke Sakai, Tomotaka Okamura, Shuya Mitoma …

Science translational medicine 15(711) eadi2623 2023年8月30日査読有り
Nsp14 of SARS-CoV-2 inhibits mRNA processing and nuclear export by targeting the nuclear cap-binding complex.

Jun Katahira, Tatsuya Ohmae, Mayo Yasugi, Ryosuke Sasaki, Yumi Itoh, Tomoko Kohda, Miki Hieda, Masami Yokota Hirai, Toru Okamoto, Yoichi Miyamoto

Nucleic acids research 2023年6月1日
A computationally designed ACE2 decoy has broad efficacy against SARS-CoV-2 omicron variants and related viruses in vitro and in vivo

Brandon Havranek, Graeme Walker Lindsey, Yusuke Higuchi, Yumi Itoh, Tatsuya Suzuki, Toru Okamoto, Atsushi Hoshino, Erik Procko, Shahidul M. Islam

Communications Biology 6(1) 2023年5月12日
Antibody feedback contributes to facilitating the development of Omicron-reactive memory B cells in SARS-CoV-2 mRNA vaccinees

Takeshi Inoue, Ryo Shinnakasu, Chie Kawai, Hiromi Yamamoto, Shuhei Sakakibara, Chikako Ono, Yumi Itoh, Tommy Terooatea, Kazuo Yamashita, Toru Okamoto …

Journal of Experimental Medicine 220(2) 2023年2月6日
An engineered ACE2 decoy neutralizes the SARS-CoV-2 Omicron variant and confers protection against infection in vivo.

Nariko Ikemura, Shunta Taminishi, Tohru Inaba, Takao Arimori, Daisuke Motooka, Kazutaka Katoh, Yuhei Kirita, Yusuke Higuchi, Songling Li, Tatsuya Suzuki …

Science translational medicine 14(650) eabn7737 2022年6月22日査読有り
Cell response analysis in SARS-CoV-2 infected bronchial organoids.

Emi Sano, Tatsuya Suzuki, Rina Hashimoto, Yumi Itoh, Ayaka Sakamoto, Yusuke Sakai, Akatsuki Saito, Daisuke Okuzaki, Daisuke Motooka, Yukiko Muramoto …

Communications biology 5(1) 516-516 2022年5月30日査読有り
SARS-CoV-2 ORF6 disrupts nucleocytoplasmic trafficking to advance viral replication.

Yoichi Miyamoto, Yumi Itoh, Tatsuya Suzuki, Tomohisa Tanaka, Yusuke Sakai, Masaru Koido, Chiaki Hata, Cai-Xia Wang, Mayumi Otani, Kohji Moriishi …

Communications biology 5(1) 483-483 2022年5月19日査読有り
Establishment of monoclonal antibodies broadly neutralize infection of hepatitis B virus.

He Zhang, Yumi Itoh, Tatsuya Suzuki, Kan-Ichiro Ihara, Tomohisa Tanaka, Saori Haga, Hajime Enatsu, Maho Yumiya, Mari Kimura, Akira Takada …

Microbiology and immunology 66(4) 179-192 2022年4月1日査読有り
Hepatitis C virus modulates signal peptide peptidase to alter host protein processing

Junki Hirano, Sachiyo Yoshio, Yusuke Sakai, Li Songling, Tatsuya Suzuki, Yumi Itoh, He Zhang, David Virya Chen, Saori Haga, Hiroko Oomori …

Proceedings of the National Academy of Sciences of the United States of America 118(22) 2021年6月1日査読有り
Engineered ACE2 receptor therapy overcomes mutational escape of SARS-CoV-2

Yusuke Higuchi, Tatsuya Suzuki, Takao Arimori, Nariko Ikemura, Emiko Mihara, Yuhei Kirita, Eriko Ohgitani, Osam Mazda, Daisuke Motooka, Shota Nakamura …

Nature Communications 12(1) 2021年6月1日査読有り
Deneddylation by SENP8 restricts hepatitis B virus propagation

David Virya Chen, Tatsuya Suzuki, Yumi Itoh, Yusuke Maeda, Junki Hirano, Saori Haga, He Zhang, Daiki Ito, Yoshiharu Matsuura, Toru Okamoto

Microbiology and Immunology 65(3) 125-135 2021年3月1日査読有り
High affinity modified ACE2 receptors protect from SARS-CoV-2 infection in hamsters

Yusuke Higuchi, Tatsuya Suzuki, Takao Arimori, Nariko Ikemura, Emiko Mihara, Yuhei Kirita, Eriko Ohgitani, Osam Mazda, Daisuke Motooka, Shota Nakamura …

2020年9月16日
Generation of human bronchial organoids for SARS-CoV-2 research

Tatsuya Suzuki, Yumi Itoh, Yusuke Sakai, Akatsuki Saito, Daisuke Okuzaki, Daisuke Motooka, Shohei Minami, Takeshi Kobayashi, Takuya Yamamoto, Toru Okamoto …

2020年5月26日査読有り
Monitoring of glutamate-induced excitotoxicity by mitochondrial oxygen consumption

Ayako Kumagai, Tsutomu Sasaki, Kenta Matsuoka, Masayoshi Abe, Toshihide Tabata, Yumi Itoh, Hiroyuki Fuchino, Sartagul Wugangerile, Mika Suga, Tomoko Yamaguchi …

Synapse 73(1) e22067-e22067 2019年1月
Carnosol suppresses interleukin-6 production in mouse lungs injured by ischemia–reperfusion operation and in RAW264.7 macrophages treated with lipopolysaccharide

Toru Momozane, Tomohiro Kawamura, Yumi Itoh, Masato Sanosaka, Tsutomu Sasaki, Ryu Kanzaki, Naoko Ose, Soichiro Funaki, Yasushi Shintani, Masato Minami …

Biochemistry and Cell Biology 96(6) 769-776 2018年12月
Simple chronic colitis model using hypopigmented mice with aHermansky-Pudlak syndrome 5gene mutation

Yumi Itoh, Yasuo Nagaoka, Yoshio Katakura, Hidehisa Kawahara, Hiroshi Takemori

Pigment Cell & Melanoma Research 29(5) 578-582 2016年9月
Corrigendum: Pterosin B prevents chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3.

Yasuhito Yahara, Hiroshi Takemori, Minoru Okada, Azuma Kosai, Akihiro Yamashita, Tomohito Kobayashi, Kaori Fujita, Yumi Itoh, Masahiro Nakamura, Hiroyuki Fuchino …

Nature communications 7 12117-12117 2016年6月27日
Pterosin B prevents chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3

Yasuhito Yahara, Hiroshi Takemori, Minoru Okada, Azuma Kosai, Akihiro Yamashita, Tomohito Kobayashi, Kaori Fujita, Yumi Itoh, Masahiro Nakamura, Hiroyuki Fuchino …

Nature Communications 7(1) 10959-10959 2016年4月22日
Pterosin B has multiple targets in gluconeogenic programs, including coenzyme Q in RORα–SRC2 signaling

Yumi Itoh, Hiroyuki Fuchino, Masato Sanosaka, Koichiro Kako, Kazumasa Hada, Akiyoshi Fukamizu, Hiroshi Takemori, Nobuo Kawahara

Biochemical and Biophysical Research Communications 473(2) 415-420 2016年4月

もっとみる

MISC

Engineered ACE2 receptor has a potential for a new therapy of COVID-19

Yumi Itoh, Hajime Enatsu, Akira Takada, Toru Okamoto

Folia Pharmacologica Japonica 157(2) 155 2022年
GRID2はメマンチンの作用機序における新しい調節因子である

熊谷彩子, 伊東祐美, 賀川舞, 松田潤一郎, 佐々木勉, 田端俊英

日本生化学会大会(Web) 87th 4T13A-02(4P-008) (WEB ONLY)-02] 2014年10月
GRID2はメマンチンの作用機序における新しい調節因子である

熊谷彩子, 伊東祐美, 賀川舞, 松田潤一郎, 佐々木勉, 田端俊英, 竹森洋

日本臨床分子医学会学術総会プログラム・抄録集 51回 95-95 2014年4月
塩誘導性キナーゼSIKは核内受容体の反応性を決定する

竹森洋, 上尾達也, 熊谷彩子, 伊東祐美, 秦野修, 早坂直人, 中村和臣, 小浦美奈子, 松田潤一郎

日本内分泌学会雑誌 86(2) 408-408 2010年9月

共同研究・競争的資金等の研究課題

フラビウイルス感染細胞のエネルギー代謝制御機構の解明

日本学術振興会科学研究費助成事業若手研究 2023年4月 - 2025年3月

伊東祐美