Yutaka Sakai

Profile Information

Affiliation: 教授, 脳科学研究所, 玉川大学

Degree: Ph.D(Kyoto University)

J-GLOBAL ID: 200901051484490556
researchmap Member ID: 1000359714

External link: http://spike.lab.tamagawa.ac.jp/index-e.html

A biological brain is an excellent learning machine. I am exploring brain functions, which have not yet been achieved by artificial computers, with multiple levels of approach from synaptic learning rules to learning behavior of animals.

Research Interests

Research Areas

Research History

Apr, 2013 - Present

Professor, Tamagawa University Brain Science Institute
Apr, 2007 - Mar, 2013

Associate Professor, Tamagawa University Brain Science Institute
Apr, 2004 - Mar, 2007

Associate Professor, College of Engineering, Tamagawa University
Apr, 2000 - Mar, 2004

Research Associate, Faculty of Engineering, Saitama University
Apr, 1997 - Mar, 2000

Ph.D course, Graduate School of Science, Kyoto University
Apr, 1995 - Mar, 1997

Master course, Graduate School of Science, Kyoto University
Apr, 1991 - Mar, 1995

Faculty of Science, Kyoto University

Awards

2000

日本神経回路学会奨励賞

Papers

Goal-oriented inference of environment from redundant observations.

Kazuki Takahashi, Tomoki Fukai, Yutaka Sakai, Takashi Takekawa

Neural networks : the official journal of the International Neural Network Society, 174 106246-106246, Jun, 2024
State-transition-free reinforcement learning in chimpanzees (Pan troglodytes).

Yutaro Sato, Yutaka Sakai, Satoshi Hirata

Learning & behavior, 51(4) 413-427, Dec, 2023
Reward expectation enhances action-related activity of nigral dopaminergic and two striatal output pathways.

Alain Rios, Satoshi Nonomura, Shigeki Kato, Junichi Yoshida, Natsuki Matsushita, Atsushi Nambu, Masahiko Takada, Riichiro Hira, Kazuto Kobayashi, Yutaka Sakai …

Communications biology, 6(1) 914-914, Sep 6, 2023
Rat hippocampal CA1 region represents learning-related action and reward events with shorter latency than the lateral entorhinal cortex.

Shogo Soma, Shinya Ohara, Satoshi Nonomura, Naofumi Suematsu, Junichi Yoshida, Eva Pastalkova, Yutaka Sakai, Ken-Ichiro Tsutsui, Yoshikazu Isomura

Communications biology, 6(1) 584-584, May 31, 2023
Automated and parallelized spike collision tests to identify spike signal projections.

Keita Mitani, Masanori Kawabata, Yoshikazu Isomura, Yutaka Sakai

iScience, 25(10) 105071-105071, Oct 21, 2022
Memory trace imbalance in reinforcement and punishment systems can reinforce implicit choices leading to obsessive-compulsive behavior.

Yuki Sakai, Yutaka Sakai, Yoshinari Abe, Jin Narumoto, Saori C Tanaka

Cell reports, 40(9) 111275-111275, Aug 30, 2022
Computerized intertemporal choice task in chimpanzees (Pan troglodytes) with/without postreward delay.

Yutaro Sato, Yutaka Sakai, Satoshi Hirata

Journal of comparative psychology (Washington, D.C. : 1983), 135(2) 185-195, May, 2021
A spike analysis method for characterizing neurons based on phase locking and scaling to the interval between two behavioral events.

Masanori Kawabata, Shogo Soma, Akiko Saiki-Ishikawa, Satoshi Nonomura, Junichi Yoshida, Alain Ríos, Yutaka Sakai, Yoshikazu Isomura

Journal of neurophysiology, 124(6) 1923-1941, Dec 1, 2020
Differential Changes in the Lateralized Activity of Identified Projection Neurons of Motor Cortex in Hemiparkinsonian Rats.

Alain Ríos, Shogo Soma, Junichi Yoshida, Satoshi Nonomura, Masanori Kawabata, Yutaka Sakai, Yoshikazu Isomura

eNeuro, 6(4) ENEURO.0110-19.2019-19.2019, Jun, 2019 Peer-reviewed
Ipsilateral-Dominant Control of Limb Movements in Rodent Posterior Parietal Cortex

Shogo Soma, Junichi Yoshida, Shigeki Kato, Yukari Takahashi, Satoshi Nonomura, Yae K. Sugimura, Alain Ríos, Masanori Kawabata, Kazuto Kobayashi, Fusao Kato …

The Journal of Neuroscience, 39(3) 485-502, Jan 16, 2019 Peer-reviewed
Monitoring and Updating of Action Selection for Goal-Directed Behavior through the Striatal Direct and Indirect Pathways.

Satoshi Nonomura, Kayo Nishizawa, Yutaka Sakai, Yasuo Kawaguchi, Shigeki Kato, Motokazu Uchigashima, Masahiko Watanabe, Ko Yamanaka, Kazuki Enomoto, Satomi Chiken …

Neuron, 99(6) 1302-1314, Sep 19, 2018 Peer-reviewed
Area-specific Modulation of Functional Cortical Activity During Block-based and Trial-based Proactive Inhibition.

Junichi Yoshida, Akiko Saiki, Shogo Soma, Ko Yamanaka, Satoshi Nonomura, Alain Ríos, Masanori Kawabata, Minoru Kimura, Yutaka Sakai, Yoshikazu Isomura

Neuroscience, 388 297-316, Sep 15, 2018 Peer-reviewed
In Vivo Spiking Dynamics of Intra- and Extratelencephalic Projection Neurons in Rat Motor Cortex.

Akiko Saiki, Yutaka Sakai, Ryoji Fukabori, Shogo Soma, Junichi Yoshida, Masanori Kawabata, Hiromu Yawo, Kazuto Kobayashi, Minoru Kimura, Yoshikazu Isomura

Cerebral cortex (New York, N.Y. : 1991), 28(3) 1024-1038, Mar 1, 2018 Peer-reviewed
Efficient Control of Theta TravelingWaves by Synchronized Inhibition through Gap Junctions and GABAergic Connections in a Hippocampal CA3 Model

Toshikazu Samura, Yutaka Sakai, Hatsuo Hayashi, Takeshi Aihara

Proceedings of the 2017 International Symposium on Nonlinear Theory and its Applications (NOLTA2017), 367-370, Dec, 2017 Peer-reviewed
Distinct Laterality in Forelimb-Movement Representations of Rat Primary and Secondary Motor Cortical Neurons with Intratelencephalic and Pyramidal Tract Projections.

Shogo Soma, Akiko Saiki, Junichi Yoshida, Alain Ríos, Masanori Kawabata, Yutaka Sakai, Yoshikazu Isomura

The Journal of neuroscience : the official journal of the Society for Neuroscience, 37(45) 10904-10916, Nov 8, 2017 Peer-reviewed
A balanced motor primitive framework can simultaneously explain motor learning in unimanual and bimanual movements.

Ken Takiyama, Yutaka Sakai

Neural networks : the official journal of the International Neural Network Society, 86 80-89, Feb, 2017 Peer-reviewed
Large-scale analysis reveals populational contributions of cortical spike rate and synchrony to behavioural functions.

Rie Kimura, Akiko Saiki, Yoko Fujiwara-Tsukamoto, Yutaka Sakai, Yoshikazu Isomura

The Journal of physiology, 595(1) 385-413, Jan 1, 2017 Peer-reviewed
Similarity in Neuronal Firing Regimes across Mammalian Species.

Yasuhiro Mochizuki, Tomokatsu Onaga, Hideaki Shimazaki, Takeaki Shimokawa, Yasuhiro Tsubo, Rie Kimura, Akiko Saiki, Yutaka Sakai, Yoshikazu Isomura, Shigeyoshi Fujisawa …

The Journal of neuroscience : the official journal of the Society for Neuroscience, 36(21) 5736-47, May 25, 2016 Peer-reviewed
Balanced motor primitive can explain generalization of motor learning effects between unimanual and bimanual movements.

Ken Takiyama, Yutaka Sakai

Scientific reports, 6 23331-23331, Mar 30, 2016 Peer-reviewed
Roles of Gap Junctions in Organizing Traveling Waves in a Hippocampal CA3 Network Model

Toshikazu Samura, Yutaka Sakai, Hatsuo Hayashi, Takeshi Aihara

ICONIP2016, Lecture Notes in Computer Science, 9947 384-392, 2016 Peer-reviewed

Misc.

Analysis of Essays on the Themes of 'Past' and 'Future'

34(1) 17-30, Jun, 2023
Working memory-based and -free reward prediction in a dual dopamine system in the basal ganglia

Tomohiko Yoshizawa, Yuuto Miyamura, Yuta Ochi, Riichiro Hira, Makoto Funahashi, Yutaka Sakai, Yilong Cui, Yoshikazu Isomura

bioRxiv (preprint), Mar, 2023
Hippocampal CA1 represents action and reward events instantly compared to the superficial and deep layers of the lateral entorhinal cortex

Shogo Soma, Shinya Ohara, Satoshi Nonomura, Junichi Yoshida, Naofumi Suematsu, Eva Pastalkova, Yutaka Sakai, Ken-Ichiro Tsutsui, Yoshikazu Isomura

bioRxiv, (preprint), Apr 1, 2022
Phasic Firings of Neurons in Motor Cortex and Striatum during Spindle on Electrocorticogram Signals

黒宮光平, 塚元葉子, 酒井裕, 礒村宜和, 藤山文乃, 佐村俊和

電子情報通信学会技術研究報告 = IEICE technical report : 信学技報, 116(424) 49-52, Jan 26, 2017
パブロフ条件づけとインストゥルメンタル条件づけが影響し合う学習行動を再現する統合計算論モデル

沖津健吾, 酒井裕

基礎心理学研究, 34(2) 301, Mar 31, 2016
Computational Model Reproducing Pavlovian-to-Instrumental Transfer

OKITSU Kengo, SAKAI Yutaka

IEICE technical report. Neurocomputing, 114(515) 145-150, Mar 16, 2015
静的・動的抑制構造によって制御されるリカレントネットワークの神経活動伝播

佐村俊和, 林初男, 酒井裕, 相原威

日本神経回路学会誌, 21(2) 50-56, Jun, 2014
27pAJ-8 Computational theory of conditioning

Sakai Yutaka, Takiyama Ken

Meeting abstracts of the Physical Society of Japan, 69(1) 301-301, Mar 5, 2014
AS-1-4 Unidirectional Spike Propagation Organized in a Recurrent Network

Samura Toshikazu, Sakai Yutaka, Hayashi Hatsuo, Aihara Takeshi

Proceedings of the IEICE General Conference, 2014 "S-7"-"S-8", Mar 4, 2014
Rational learning strategy behind irrational behavior(The 30th Annual Meeting)

SAKAI Yutaka

The Japanese Journal of Psychonomic Science, 31(2) 187-191, Mar, 2013
長期抑圧の調節によるリカレントネットワークに生じる距離に依存する結合強度分布と指向性興奮伝搬への影響

佐村俊和, 杉崎えり子, 酒井裕, 林初男, 相原威

電子情報通信学会技術研究報告（NC）, 112(227) 73-78, Oct, 2012
25pTD-14 Reconsideration of temporal discount in reinforcement learning

Yamaguchi Yoshiya, Sakai Yutaka

Meeting abstracts of the Physical Society of Japan, 66(1) 292-292, Mar 3, 2011
Ensemble spiking activities in rat motor cortex during externally- and internally-initiated movements

Rie Kimura, Yutaka Sakai, Akiko Saiki, Yoko Fujiwara-Tsukamoto, Yoshikazu Isomura

NEUROSCIENCE RESEARCH, 71 E348-E348, 2011
The reward-maximization learning indifferent to historical state reproduces the preference reversal in intertemporal choice

Yoshiya Yamaguchi, Yutaka Sakai

NEUROSCIENCE RESEARCH, 71 E408-E408, 2011
サイエンスコラムシナプス可塑性と学習--新たな学習原理の発見へ

酒井裕

未来材料, 10(8) 67-72, Aug, 2010
Purpose or Strategy? Reconsideration of temporal discount in non-Markov situation

Yoshiya Yamaguchi, Yutaka Sakai

NEUROSCIENCE RESEARCH, 68 E437-E437, 2010
Reinforcement meta-learning rule solves the distal reward problem

ARAKI Shojiro, SAKAI Yutaka

IEICE technical report, 108(383) 79-83, Jan 12, 2009
「学習行動主義」のススメ

酒井裕

日本神経回路学会誌, 16(3) 141-142, 2009
26pXD-7 BCM-type synaptic plasticity using the sliding threshold as linear summation of calcium concentration

Kurashige Hiroki, Sakai Yutaka

Meeting abstracts of the Physical Society of Japan, 61(2) 246-246, Aug 18, 2006
BCM-type synaptic plasticity using the threshold as linear summation of calcium concentration

KURASHIGE Hiroki, SAKAI Yutaka

IEICE technical report, 105(657) 45-50, Mar 15, 2006

Books and Other Publications

CLINICAL NEUROSCIENCE Vol.41 No.8【特集】時間の神経科学―時を生み出すこころと脳の仕組み

(Role: Contributor, 離れた時間を結びつける学習とその障がい)

中外医学社, Aug, 2023
Matching law

Yutaka Sakai

Feb, 2013 Peer-reviewed
応用数理ハンドブック

酒井裕 (Role: Contributor, “神経回路と強化学習”, 第I編, pp. 116-117)

朝倉書店, 2013 (ISBN: 9784254111415)

Presentations

過去・現在・未来をつなぐ学習のメカニズム

酒井裕

「意志創発の進化・脳・心理基盤」次世代脳2017年度冬のシンポジウム, Dec 20, 2017 Invited
Defect of prospective and retrospective time scales in reinforcement learning behind Obsessive Compulsive Disorder

Yutaka Sakai

The 2nd International Symposium on the Science of Mental Time, Sep. 12-13, 2017, Nara, Japan, Sep 13, 2017 Invited
Computational model of Obsessive-Compulsive Disorder (OCD)

Yutaka Sakai, Yuki Sakai, Saori C Tanaka

The 40th Annual Meeting of the Japan Neuroscience Society, Jul 21, 2017 Invited
A model-based reinforcement learning model using Rescorla-Wagner principle reproduces Pavlovian-to-Instrumental Transfer

Okitsu K, Sakai Y

Neuroscience 2016, The Annual Meeting of the Society for Neuroscience, San Diego, CA, USA, Nov 11-16, 2016, Nov 16, 2016
Computational model of Obsessive-Compulsive Disorder

utaka Sakai, Tamagawa Uni, Yuki Sakai (ATR, Kyoto Prefectural, Univ. of Me, Saori C Tanaka

Workshop on the Mechanism of Brain and Mind 2016, Jan 6, 2016
Roles of Gap Junctions in Organizing Traveling Waves in a Hippocampal CA3 Network Model.

Toshikazu Samura, Yutaka Sakai, Hatsuo Hayashi, Takeshi Aihara

Neural Information Processing - 23rd International Conference, ICONIP 2016, Kyoto, Japan, October 16-21, 2016, Proceedings, Part I, 2016
Interpretation of inter-spike interval statistics through the Markov switching Poisson process

Y Sakai, S Yoshizawa, H Ohno

8TH INTERNATIONAL CONFERENCE ON NEURAL INFORMATION PROCESSING, VOLS 1-3, PROCEEDING, 2001, FUDAN UNIV PRESS

Research Projects

時間に関連した認知機能の進化的基盤を探る

科学研究費助成事業, 基盤研究(A), 日本学術振興会, Apr, 2023 - Mar, 2028

平田聡, 黒島妃香, 酒井裕
Chronogenesis: how the mind generates time

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area), Japan Society for the Promotion of Science, Jun, 2018 - Mar, 2023
Ontogeny and phylogeny of the acquisition of time

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area), Japan Society for the Promotion of Science, Jun, 2018 - Mar, 2023
Development of computational models of mental disorders and evaluation of therapeutic effects by simulation

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2016 - Mar, 2020

Saori Tanaka
Neural mechanisms of adaptive circuit shift in operant learning of behaviors

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area), Japan Society for the Promotion of Science, Jul, 2014 - Mar, 2019

ISOMURA Yoshikazu
Exploring mental time using theoretical frameworks for conditionings with delays

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area), Japan Society for the Promotion of Science, Apr, 2016 - Mar, 2018
時間割引から探るこころの時間～異種間比較の枠組構築

科学研究費助成事業, 新学術領域研究(研究領域提案型), 日本学術振興会, Apr, 2014 - Mar, 2016

酒井裕
Derivation of a learning principle from irrational behaviors

Grants-in-Aid for Scientific Research, Grant-in-Aid for Young Scientists (B), Japan Society for the Promotion of Science, 2009 - 2012

SAKAI Yutaka
Mechanism of self-organization induced by the interaction of different inputs

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area), Japan Society for the Promotion of Science, 2009 - 2012

AIHARA Takeshi, SAKAI Yutaka, FUJII Stoshi, TSUKADA Minoru
情報源に依存したマッチング行動

科学研究費補助金(特定領域研究), 特定領域研究, 文部科学省, 2008 - 2009

酒井裕
A study of information representation in learning and memory and its application to artificial models.

Grants-in-Aid for Scientific Research(基盤研究(A)), 基盤研究(A), Ministry of Education, Culture, Sports, Science and Technology, 2007 - 2009

Minoru TSUKADA, 小島比呂志, 大森隆司, 岡田浩之, 酒井裕, 奥田次郎, 小島比呂志, 大森隆司, 岡田浩之, 酒井裕, 奥田次郎
マルチニューロンデータのスパイク高次相関の解析

科学研究費補助金(特定領域研究), 特定領域研究, 文部科学省, 2006 - 2007

酒井裕
神経細胞集団のスパイク高次相関の解析と回路特性としての解釈

科学研究費補助金(特定領域研究), 特定領域研究, 文部科学省, 2005 - 2005

酒井裕
発火時刻依存学習則により形成される神経回路構造とその集団発火統計

科学研究費補助金(特定領域研究), 特定領域研究, 文部科学省, 2004 - 2004

酒井裕
神経細胞集団の回路構造とその集団発火統計

科学研究費補助金(特定領域研究), 特定領域研究, 文部科学省, 2003 - 2003

酒井裕
神径細胞集団の連鎖を伝播する集団発火活動と情報表現

科学研究費補助金(特定領域研究), 特定領域研究, 文部科学省, 2002 - 2002

酒井裕
スパイクの独立性の維持機構に関する研究

科学研究費補助金(特定領域研究(C)), 特定領域研究(C), 文部科学省, 2001 - 2001

酒井裕

Education

Apr, 1995 - Mar, 2000

Graduate School of Science, Kyoto University
Apr, 1991 - Mar, 1995

Faculty of Science, Kyoto University

Industrial Property Rights

特許第6970957号投射先同定装置、投射先同定方法及びプログラム

酒井裕, 礒村宜和