Yutaka Satou - My portal

Profile Information

Affiliation: 准教授, 大学院理学研究科生物科学専攻, 京都大学

Degree: 博士（理学）(京都大学)

J-GLOBAL ID: 201401073844191800
researchmap Member ID: B000240950

External link: http://develop.zool.kyoto-u.ac.jp/

Research Interests

Research Areas

Research History

Apr, 2007 - Present

Associate professor, Graduate School of Science, Kyoto University
Aug, 2004 - Mar, 2007

Associate professor, Graduate School of Science, Kyoto University
Oct, 2005 - Sep, 2006

客員研究員, 米国UCバークレイ
Jul, 1999 - Jul, 2004

Assistant professor, Graduate School of Science, Kyoto University

Education

Apr, 1994 - Mar, 1999

Graduate School of Science, Kyoto University
Apr, 1990 - Mar, 1994

Faculty of Science, Kyoto University

Awards

Dec, 2018

日本動物学会学会賞, 公益社団法人日本動物学会

佐藤ゆたか
Feb, 2014

JSPS PRIZE, Japan Society of the Promotion of Science

Yutaka Satou

Major Papers

154

Ascidian embryonic cells with properties of neural-crest cells and neuromesodermal progenitors of vertebrates

Tasuku Ishida, Yutaka Satou

Nature Ecology & Evolution, Apr 2, 2024
A digital twin reproducing gene regulatory network dynamics of early Ciona embryos indicates robust buffers in the network

Miki Tokuoka, Yutaka Satou

PLOS Genetics, 19(9), Sep 27, 2023 Peer-reviewedLast authorCorresponding author
Regulators specifying cell fate activate cell cycle regulator genes to determine cell numbers in ascidian larval tissues

Kenji Kobayashi, Miki Tokuoka, Hiroaki Sato, Manami Ariyoshi, Shiori Kawahara, Shigeki Fujiwara, Takeo Kishimoto, Yutaka Satou

Development, Nov 15, 2022 Peer-reviewedLast author
Chromosomal Inversion Polymorphisms in Two Sympatric Ascidian Lineages

Yutaka Satou, Atsuko Sato, Hitoyoshi Yasuo, Yukie Mihirogi, John Bishop, Manabu Fujie, Mayumi Kawamitsu, Kanako Hisata, Noriyuki Satoh

Genome Biology and Evolution, 13(6), Jun 8, 2021 Peer-reviewedLead authorCorresponding author
The gene regulatory system for specifying germ layers in early embryos of the simple chordate

Miki Tokuoka, Kazuki Maeda, Kenji Kobayashi, Atsushi Mochizuki, Yutaka Satou

Science Advances, 7(24) eabf8210-eabf8210, Jun, 2021 Peer-reviewedLast authorCorresponding author
Two distinct motifs for Zic-r.a drive specific gene expression in two cell lineages

Izumi Oda-Ishii, Deli Yu, Yutaka Satou

Development, 148(11), Jun 1, 2021 Peer-reviewedLast authorCorresponding author
A Nearly Complete Genome of Ciona intestinalis Type A (C. robusta) Reveals the Contribution of Inversion to Chromosomal Evolution in the Genus Ciona

Yutaka Satou, Ryohei Nakamura, Deli Yu, Reiko Yoshida, Mayuko Hamada, Manabu Fujie, Kanako Hisata, Hiroyuki Takeda, Noriyuki Satoh

Genome biology and evolution, 11(11) 3144-3157, Nov 1, 2019 Peer-reviewedLead authorCorresponding author
Foxg specifies sensory neurons in the anterior neural plate border of the ascidian embryo

Boqi Liu, Yutaka Satou

Nature Communications, 10 4911, Oct 29, 2019 Peer-reviewedLast authorCorresponding author
The regulatory pathway from genes directly activated by maternal factors to muscle structural genes in ascidian embryos

Deli Yu, Izumi Oda-Ishii, Atsushi Kubo, Yutaka Satou

Development, 146(3) dev.173104, Jan 1, 2019 Peer-reviewedLast authorCorresponding author
Initiation of the zygotic genetic program in the ascidian embryo

Oda-Ishii, I., Satou, Y.

Semin Cell Dev Biol, 84 111-117, Dec, 2018 Peer-reviewedLast authorCorresponding author
Controlling Cell Fate Specification System by Key Genes Determined from Network Structure

Kenji Kobayashi, Kazuki Maeda, Miki Tokuoka, Atsushi Mochizuki, Yutaka Satou

iScience, 4 281-293, Jun, 2018 Peer-reviewedLast authorCorresponding author
Distinct regulation of Snail in two muscle lineages of the ascidian embryo achieves temporal coordination of muscle development

Miki Tokuoka, Kenji Kobayashi, Yutaka Satou

Development, 145(11) dev.163915, Jun, 2018 Peer-reviewedLast authorCorresponding author
Differential gene expression along the animal-vegetal axis in the ascidian embryo is maintained by a dual functional protein Foxd

Shin-ichi Tokuhiro, Miki Tokuoka, Kenji Kobayashi, Atsushi Kubo, Izumi Oda-Ishii, Yutaka Satou

PLOS GENETICS, 13(5) e1006741, May, 2017 Peer-reviewedLast authorCorresponding author
Differential temporal control of Foxa.a and Zic-r.b specifies brain versus notochord fate in the ascidian embryo

Tatsuro Ikeda, Yutaka Satou

DEVELOPMENT, 144(1) 38-43, Jan, 2017 Peer-reviewedLast authorCorresponding author
Tfap2 and Sox1/2/3 cooperatively specify ectodermal fates in ascidian embryos

Kaoru S. Imai, Hiroki Hikawa, Kenji Kobayashi, Yutaka Satou

DEVELOPMENT, 144(1) 33-37, Jan, 2017 Peer-reviewedLast authorCorresponding author
Antagonism between beta-catenin and Gata. a sequentially segregates the germ layers of ascidian embryos

Kaoru S. Imai, Clare Hudson, Izumi Oda-Ishii, Hitoyoshi Yasuo, Yutaka Satou

DEVELOPMENT, 143(22) 4167-4172, Nov, 2016 Peer-reviewedLast authorCorresponding author
A Maternal System Initiating the Zygotic Developmental Program through Combinatorial Repression in the Ascidian Embryo

Izumi Oda-Ishii, Atsushi Kubo, Willi Kari, Nobuhiro Suzuki, Ute Rothbaecher, Yutaka Satou

PLOS GENETICS, 12(5) e1006045, May, 2016 Peer-reviewedLast authorCorresponding author
Genetic pathways for differentiation of the peripheral nervous system in ascidians

Kana Waki, Kaoru S. Imai, Yutaka Satou

NATURE COMMUNICATIONS, 6, Oct, 2015 Peer-reviewedLast authorCorresponding author
Sustained Heterozygosity Across a Self-Incompatibility Locus in an Inbred Ascidian

Yutaka Satou, Kazuko Hirayama, Kaoru Mita, Manabu Fujie, Shota Chiba, Reiko Yoshida, Toshinori Endo, Yasunori Sasakura, Kazuo Inaba, Nori Satoh

MOLECULAR BIOLOGY AND EVOLUTION, 32(1) 81-90, Jan, 2015 Peer-reviewedLead authorCorresponding author
A time delay gene circuit is required for palp formation in the ascidian embryo

Ikeda Tatsuro, Matsuoka Terumi, Satou Yutaka

Development, 140(23) 4703-4708, 2013 Peer-reviewedLast authorCorresponding author
Multiple Signaling Pathways Coordinate to Induce a Threshold Response in a Chordate Embryo

Ohta Naoyuki, Satou Yutaka

Plos Genetics, 9(10), 2013 Peer-reviewedLast authorCorresponding author
Cis-Acting Transcriptional Repression Establishes a Sharp Boundary in Chordate Embryos

Kaoru S. Imai, Yutaka Daido, Takehiro G. Kusakabe, Yutaka Satou

SCIENCE, 337(6097) 964-967, Aug, 2012 Peer-reviewedLast authorCorresponding author
Genomic cis-regulatory networks in the early Ciona intestinalis embryo

Atsushi Kubo, Nobuhiro Suzuki, Xuyang Yuan, Kenta Nakai, Nori Satoh, Kaoru S. Imai, Yutaka Satou

DEVELOPMENT, 137(10) 1613-1623, May, 2010 Peer-reviewedLast authorCorresponding author
Gene regulatory networks underlying the compartmentalization of the Ciona central nervous system

Kaoru S. Imai, Alberto Stolfi, Michael Levine, Yutaka Satou

DEVELOPMENT, 136(2) 285-293, Jan, 2009 Peer-reviewedLast authorCorresponding author
Improved genome assembly and evidence-based global gene model set for the chordate Ciona intestinalis: new insight into intron and operon populations

Yutaka Satou, Katsuhiko Mineta, Michio Ogasawara, Yasunori Sasakura, Eiichi Shoguchi, Keisuke Ueno, Lixy Yamada, Jun Matsumoto, Jessica Wasserscheid, Ken Dewar …

GENOME BIOLOGY, 9(10), 2008 Peer-reviewedLead authorCorresponding author
Regulatory blueprint for a chordate embryo

KS Imai, M Levine, N Satoh, Y Satou

SCIENCE, 312(5777) 1183-1187, May, 2006 Peer-reviewedLast authorCorresponding author
Genomic overview of mRNA 5'-leader trans-splicing in the ascidian Ciona intestinalis

Yutaka Satou, Makoto Hamaguchi, Keisuke Takeuchi, Kenneth E. M. Hastings, Nori Satoh

NUCLEIC ACIDS RESEARCH, 34(11) 3378-3388, 2006 Peer-reviewedLead authorCorresponding author
Gene expression profiles of transcription factors and signaling molecules in the ascidian embryo: towards a comprehensive understanding of gene networks

KS Imai, K Hino, K Yagi, N Satoh, Y Satou

DEVELOPMENT, 131(16) 4047-4058, Aug, 2004 Peer-reviewedLast authorCorresponding author
The ascidian Mesp gene specifies heart precursor cells

Y Satou, KS Imai, N Satoh

DEVELOPMENT, 131(11) 2533-2541, Jun, 2004 Peer-reviewedLead authorCorresponding author
A zinc finger transcription factor, ZicL, is a direct activator of Brachyury in the notochord specification of Ciona intestinalis

K Yagi, Y Satou, N Satoh

DEVELOPMENT, 131(6) 1279-1288, Mar, 2004 Peer-reviewed
A Twist-like bHLH gene is a downstream factor of an endogenous FGF and determines mesenchymal fate in the ascidian embryos

KS Imai, N Satoh, Y Satou

DEVELOPMENT, 130(18) 4461-4472, Sep, 2003 Peer-reviewedLast authorCorresponding author
The draft genome of Ciona intestinalis: Insights into chordate and vertebrate origins

P Dehal, Y Satou, RK Campbell, J Chapman, B Degnan, A De Tomaso, B Davidson, A Di Gregorio, M Gelpke, DM Goodstein …

SCIENCE, 298(5601) 2157-2167, Dec, 2002 Peer-reviewedLead author
An essential role of a FoxD gene in notochord induction in Ciona embryos

Imai, KS, Satoh, N, Satou, Y

Development, 129(14) 3441-3453, Jul 15, 2002 Peer-reviewedLast author
Multiple functions of a Zic-like gene in the differentiation of notochord, central nervous system and muscle in Ciona savignyi embryos

KS Imai, Y Satou, N Satoh

DEVELOPMENT, 129(11) 2723-2732, Jun, 2002 Peer-reviewedLead author
Early embryonic expression of FGF4/6/9 gene and its role in the induction of mesenchyme and notochord in Ciona savignyi embryos

Imai, KS, Satoh, N, Satou, Y

Development, 129(7) 1729-1738, Apr 1, 2002 Peer-reviewedLast author
Early embryonic expression of a LIM-homeobox gene Cs-lhx3 is downstream of beta-catenin and responsible for the endoderm differentiation in Ciona savignyi embryos

Y Satou, KS Imai, N Satoh

DEVELOPMENT, 128(18) 3559-3570, Sep, 2001 Peer-reviewedLead authorCorresponding author
Gene expression profiles in Ciona intestinalis tailbud embryos

Satou, Y, Takatori, N, Yamada, L, Mochizuki, Y, Hamaguchi, M, Ishikawa, H, Chiba, S, Imai, K, Kano, S, Murakami, SD …

Development, 128(15) 2893-2904, Aug 1, 2001 Peer-reviewedLead author
beta-catenin mediates the specification of endoderm cells in ascidian embryos

K Imai, N Takada, N Satoh, Y Satou

DEVELOPMENT, 127(14) 3009-3020, Jul, 2000 Peer-reviewedLast author

Misc.

A gene regulatory network for cell fate specification in Ciona embryos

Yutaka Satou

Current Topics in Developmental Biology, 2020 Peer-reviewed
High-Throughput Protein Production Combined with High- Throughput SELEX Identifies an Extensive Atlas of Ciona robusta Transcription Factor DNA-Binding Specificities

Kazuhiro R Nitta, Renaud Vincentelli, Edwin Jacox, Agnès Cimino, Yukio Ohtsuka, Daniel Sobral, Yutaka Satou, Christian Cambillau, Patrick Lemaire

High-Throughput Protein Production and Purification (Methods and Protocols), 487-517, 2019 Peer-reviewed
Microinjection of Exogenous Nucleic Acids into Eggs: Ciona Species

Kenji Kobayashi, Yutaka Satou

Transgenic Ascidians, 1029 5-13, 2018 Peer-reviewed
Ascidian Zic Genes

Satou Y, Imai K. S

Adv Exp Med Biol, 1046 87-106, 2018 Invited
Embryonic developmental system in Ciona intestinalis

Protein, nucleic acid and enzyme, 52(8) 833-841, Jul, 2007
Urochordate genomes

Satoh N, Kawashima T, Shoguchi E, Satou Y, Volff J

Vertebrate Genomes, 2 198-212, 2006 Peer-reviewed
発生・進化メカニズムホヤ発生ゲノム科学の新展開 (ゲノムから生命システムへ) -- (ゲノムから生物学)

川島武士, 將口栄一, 佐藤ゆたか

蛋白質核酸酵素, 50(16) 2153-2159,2032, Dec, 2005
ゲノムからみたホヤの発生と進化 (発生システムのダイナミクス) -- (進化)

佐藤ゆたか, 佐藤矩行

蛋白質核酸酵素, 50(6) 774-778,499, May, 2005
Genome Science of Ciona intestinalis : Its Recent Progress(Comparative Genomics of Animals,Symposium,PROCEEDING OF THE 76^<TH> ANNUAL MEETING OF THE ZOOLOGICAL SOCIETY OF JAPAN) :

Satoh Nori, Satou Yutaka, Kawashima Takeshi, Shoguchi Eiichi

Zoological science, 22(12) 1377-1378, 2005
Special Review ホヤのゲノムワイドな遺伝子科学:脊索動物の普遍的な生命現象の理解を目指して

佐藤ゆたか, 佐藤矩行

細胞工学, 22(9) 1003-1008, Sep, 2003
Special Review ホヤ・ゲノムの解読:動物の進化・比較ゲノム科学の新展開

佐藤矩行, 佐藤ゆたか, 小原雄治

細胞工学, 22(7) 776-783, Jul, 2003
ゲノム情報ホヤゲノム解読の意義

佐藤ゆたか, 佐藤矩行

蛋白質核酸酵素, 48(9) 1282-1286, Jul, 2003
THE ROLE OF FGF9/16/20 IN THE FORMATION OF MESENCHYME CELLS AND TRUNK LATERAL CELLS IN CIONA INTESTINALIS EMBRYOS(Developmental Biology,Abstracts of papers presented at the 74^<th> Annual Meeting of the Zoological Society of Japan) :

Tokuoka Miki, Imai Kaoru, Satou Yutaka, Satoh Nori

Zoological science, 20(12) 1568-1569, 2003
EXPRESSION OF NOVEL ENDOSTYLE-SPECIFIC GENES IN CIONA INTESTINALIS(Taxonomy and Systematics)(Proceedings of the Seventy-Third Annual Meeting of the Zoological Society of Japan) :

Miyamoto Yuki, Sasaki Akane, Satou Yutaka, Satoh Noriyuki, Ogasawara Michio

Zoological science, 19(12) 1426-1426, 2002
脊索動物モデルのホヤ発生の遺伝子システム (ゲノムサイエンスの新たなる挑戦) -- (第2部ゲノムの機能解析から生命の多様性に迫る 2.多細胞生物へ)

佐藤矩行, 佐藤ゆたか

蛋白質核酸酵素, 46(16) 2451-2455, Dec, 2001
ホヤのゲノム科学:発生生物学の新たな展開 (特集ゲノム研究から見た21世紀の生命科学)

佐藤矩行, 佐藤ゆたか

細胞工学, 20(1) 51-56, Jan, 2001
EXPRESSION PATTERNS OF THREE BRAIN VESICLE-SPECIFIC GENES DURING EMBRYOGENESIS OF THE ASCIDIAN CIONA INTESTINALIS(Developmental Biology)(Proceeding of the Seventy-Third Annual Meeting of the Zoological Society of Japan) :

Kusakabe R., Kusakabe T., Kawakami I., Satou Y., Satoh N., Tsuda M.

Zoological science, 18 69-69, 2001
Genes expressed in mesendodermal cells in Hemicentrotus pulcherrimus(Developmental Biology)(Proceeding of the Seventy-Third Annual Meeting of the Zoological Society of Japan) :

Tokuoka Miki, Shoguchi Eiichi, Nagai Aki, Honda Yuko, Satou Yutaka, Satoh Noriyuki, Kominami Tetsuya

Zoological science, 18 80-80, 2001

Research Projects

Construction mechanism of basic design for adaptive neuronal circuits

Grants-in-Aid for Scientific Research Grant-in-Aid for Transformative Research Areas (A), Grant-in-Aid for Transformative Research Areas (A), Japan Society for the Promotion of Science, Sep, 2021 - Mar, 2026
ホヤ初期胚の細胞運命決定機構

科学研究費助成事業基盤研究(B), 基盤研究(B), 日本学術振興会, Apr, 2021 - Mar, 2024

佐藤ゆたか
再構成された遺伝調節ネットワークで胚発生の遺伝子発現変化を論理的に再現する

科学研究費助成事業基盤研究(B), 基盤研究(B), 日本学術振興会, Jul, 2017 - Mar, 2022

佐藤ゆたか
Development of a tool for measuring the activity of core promoters using animal early embryos

Grants-in-Aid for Scientific Research Grant-in-Aid for Challenging Exploratory Research, Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, Apr, 2015 - Mar, 2017

Satou Yutaka
DNAループによる転写調節機構の解明

科学研究費補助金(新学術領域研究(研究領域提案型)), 新学術領域研究(研究領域提案型), 文部科学省, 2013 - 2014

佐藤ゆたか
ゲノムワイドな遺伝子ネットワーク解析による脊索動物の発生と進化のシステム的理解

科学研究費補助金(若手研究(S)), 若手研究(S), 文部科学省, 2009 - 2013

佐藤ゆたか
ホヤ胚発生を支配する転写制御ネットワーク

科学研究費補助金(若手研究(A)), 若手研究(A), 文部科学省, 2008 - 2009

佐藤ゆたか
ホヤ胚発生の包括的理解のための遺伝子発現アトラスの作製にむけた試み

科学研究費補助金(萌芽研究, 挑戦的萌芽研究), 萌芽研究, 挑戦的萌芽研究, 文部科学省, 2008 - 2009

佐藤ゆたか
ホヤ初期胚発生におけるゲノムワイドな転写因子ネットワークの解析

科学研究費補助金(若手研究(A)), 若手研究(A), 文部科学省, 2005 - 2007

佐藤ゆたか
ホヤゲノムにおける5'スプライスリーダー配列をもつmRNAの網羅的解析

科学研究費補助金(特定領域研究), 特定領域研究, 文部科学省, 2005 - 2005

佐藤ゆたか, 佐藤矩行
Mechanism of evolution and structure of developmental systems

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research on Priority Areas, Grant-in-Aid for Scientific Research on Priority Areas, Japan Society for the Promotion of Science, 2001 - 2005

NOJI Sumihare, SATOU Yutaka, KURATANI Shigeru, AKASAKA Koji, HASEBE Mitsuyasu
ホヤ胚の内胚葉分化と中胚葉誘導における分子機構の解明

科学研究費補助金(若手研究(A)), 若手研究(A), 文部科学省, 2002 - 2004

佐藤ゆたか
ホヤ胚の筋肉細胞分化決定機構の解析

科学研究費補助金(奨励研究(A)), 奨励研究(A), 文部科学省, 2000 - 2001

佐藤ゆたか
ホヤ胚の筋肉および内胚葉細胞分化における内在的決定機構の解析

科学研究費助成事業特別研究員奨励費, 特別研究員奨励費, 日本学術振興会, 1999 - 1999

佐藤ゆたか
ホヤ胚の筋肉細胞分化における筋肉アクチン遺伝子の特異的発現調節機構の解析

科学研究費助成事業特別研究員奨励費, 特別研究員奨励費, 日本学術振興会, 1998 - 1998

佐藤ゆたか