Division of Bioscience and Biotechnology for Future Bioindustries Department of Applied Bioorganic Chemistry, Graduate School of Agriculture, Tohoku University
Apr 2011
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Mar 2013
Division of Bioscience and Biotechnology for Future Bioindustries Department of Applied Bioorganic Chemistry, Graduate School of Agriculture, Tohoku University
Isolation and Biological Activity of 8-Epitetrodotoxin and the Structure of a Possible Biosynthetic Shunt Product of Tetrodotoxin, Cep-226A, from the Newt Cynops ensicauda popei
Yuta Kudo, Mari Yotsu-Yamashita
Journal of Natural Products 82(6) 1656-1663 May 2019 [Refereed]
Total syntheses and determination of absolute configurations of Cep-212 and Cep-210, predicted biosynthetic intermediates of tetrodotoxin isolated from toxic newt
Masaatsu Adachi, Tadachika Miyasaka, Yuta Kudo, Keita Sugimoto, Mari Yotsu-Yamashita, and Toshio Nishikawa
Organic Letters 21(3) 780-784 Jan 2019 [Refereed]
Structural Elucidation of Trace Components Combining GC/MS, GC/IR, DFT‐Calculation and Synthesis—Salinilactones, Unprecedented Bicyclic Lactones from Salinispora Bacteria
Christian Schlawis, Simone Kern, Yuta Kudo, Jörg Grunenberg, Bradley S. Moore, Stefan Schulz
Angewandte Chemie International Edition 2018 [Refereed]
Spiro bicyclic guanidino compounds from pufferfish, possible biosynthetic intermediates of tetrodotoxin in marine environments
Nozomi Ueyama, Keita Sugimoto, Yuta Kudo, Ken-ichi Onodera, Yuko Cho, Keiichi Konoki, Toshio Nishikawa, Mari Yotsu-Yamashita
Chemistry, a European Journal 24(28) 7250-7258 2018 [Refereed]
Comparative transcriptomics as a guide to natural product discovery and biosynthetic gene cluster functionality
Gregory C. A. Amos, Takayoshi Awakawa, Robert N. Tuttle, Anne-Catrin Letzel, Min Cheol Kim, Yuta Kudo, William Fenical, Bradley S. Moore, Paul R. Jensen
Proceedings of the National Academy of Sciences USA 114 11121-11130 2017 [Refereed]
Identification of new analogs and putative biosynthetic intermediates of tetrodotoxin aimed at elucidating its biosynthetic pathway and structure activity relationship
Yuta Kudo, Mari Yotsu-Yamashita
60 th American Society of Pharmacognosy Annual Meeting 2019 16 Jul 2019
Administration of possible biosynthetic intermediates of tetrodotoxin to tetrodotoxin possessing animals
Keita Sugimoto, Yuta Kudo, Tadachika Miyasaka, Masaatsu Adachi, Yuko Cho, Keiichi Konoki, Chikafumi Chiba, Toshio Nishikawa, Mari Yotsu-Yamashita
26 Mar 2019
Structures and bioactivities of new tetrodotoxin analogue and biosynthetic shunt compound from the newt
Yuta Kudo, Mari Yotsu-Yamashita
26 Mar 2019
Analysis of paralytic shellfish toxins in the scallop cultured in a coast of eastern Japan by LC-MS/MS
Satoshi Numano, Yuta Kudo, Yuko Cho, Keiichi Konoki, Mari Yotsu-Yamashita
26 Mar 2019
Total Syntheses and Determination of Absolute Configurations of Predicted Biosynthetic Intermediates of Tetrodotoxin
Tadachika Miyasaka, Masaatsu Adachi, Yuta Kudo, Keita Sugimoto, Mari Yotsu-Yamashita, Toshio Nishikawa
24 Mar 2019
Investigations of the biosynthesis and signaling function of salinipostin, an unusual phosphotriester gamma-butyrolactone compound from Salinispora
Yuta Kudo, Takayoshi Awakawa, Yi-Ling Du, Peter Jordan, Katherine Ryan, Rojer Linington and Bradley S. Moore
2nd International Conference on Natural Product Discovery and Development in the Genomic Era, Society for Industrial Microbiology & Biotechnology Jan 2018
Prediction of biosynthetic pathways of tetrodotoxin and saxitoxin on the basis of the structures of their intermediates
Mari Yotsu-Yamashita, Yuta Kudo, Shigeki Tsuchiya, Yuko Cho, and Keiichi Konoki
US-Japan Symposium in Marine Bioorganic Chemistry: 21st Century Innovations in Natural Products Nov 2016
Screening of bioactive compounds in pufferfish and marine invertebrates from Solomon Islands
Clyde Gorapava Puilingi, Yuta Kudo、Keiichi Konoki、Yuko Cho、Mari Yotsu-Yamashita
Mar 2016
Screening and structure elucidation of the possible biosynthetic intermediates of tetrodotoxin from the newts
Yuta Kudo, Yuko Cho, Keiichi Konoki and Mari Yotsu-Yamashita
The 2015 International Chemical Congress of Pacific Basin Societies Dec 2015
Our recent studies of tetrodotoxin, saxitoxin and polycavernosides
Mari Yotsu-Yamashita, Yuta Kudo, Shigeki Tsuchiya, Kosuke Maeta, Yuko Cho, Keiichi Konoki
The 2015 International Chemical Congress of Pacific Basin Societies Dec 2015
Identification of analogues and biosynthetic intermediates of tetrodotoxin aimed at elucidating its biosynthesis[Invited]
Yuta Kudo
Tohoku University’s Chemistry Summer School 2015 Aug 2015
Tetrodotoxin study in pufferfish and screening of bioactive compounds in marine invertebrates from Solomon Islands
Clyde Gorapava Puilingi, Yuta Kudo, Keiichi Konoki, Yuko Cho and Mari Yotsu-Yamashit
Tohoku University’s Chemistry Summer School 2015 Aug 2015
Investigation of tetrodotoxin in pufferfish and screening of bioactive compounds in marine invertebrates from Solomon Islands
Clyde Gorapava Puilingi, Yuta Kudo、Keiichi Konoki、Yuko Cho、Mari Yotsu-Yamashita
Mar 2015
Screening of New Tetrodotoxin Analogues Using HILIC-LC-MS/MS and Their Structure Determination
Yuta Kudo, Keiichi Konoki, Yuko Cho and Mari Yotsu-Yamashita
Tohoku University’s Chemistry Summer school Aug 2014
Screening of tetrodotoxin in pufferfish from Solomon Islands
Clyde Gorapava Puilingi, Yuta Kudo, Keiichi Konoki, Yuko Cho, Mari Yotsu-Yamashita
Tohoku University’s Chemistry Summer school Aug 2014
Approach to elucidation of biosynthetic pathways towards tetrodotoxin and saxitoxin
Mari Yotsu-Yamashita, Yuta Kudo, Shigeki Tsuchiya, Yuko Cho, Keiichi Konoki
Tohoku University’s Chemistry Summer school Aug 2014
Structure elucidation of 10-hemiketal-type tetrodotoxin analogues, indicative of the biosynthetic pathway
Yuta Kudo, Yoko Yamashita, Keiichi Konoki, Yuko Cho, Takeshi Yasumoto and Mari Yotsu-Yamashita
Gordon Research Conference: Natural Products Jul 2014
The first identification of the novel tetrodotoxin analog, 6-deoxytetrodotoxin, and its biological activity
Yuta Kudo, Keiichi Konoki, Yuko Cho and Mari Yotsu-Yamashita
The American Society of Pharmacognosy’s 2013 annual meeting Sep 2013
The structure of the novel tetrodotoxin analog, 6-deoxytetrodotoxin, and structure activity relationship study on C-6 and C-11 hydroxyl groups of tetrodotoxin
Yuta Kudo, Keiichi Konoki, Yuko Cho, and Mari Yotsu-Yamashita
Sep 2013
Identification of 5,11-dideoxytetrodotoxin in marine animals, and characterization of ESI-MS fragment ions of tetrodotoxin and its analogs
Mari Yotsu-Yamashita, Yuka Abe, Yuta Kudo, Keiichi Konoki, Yuko Cho, Toshio Nishikawa, Minoru Isobe
Sep 2013
Isolation and Structural Determination of the First 8-epi-type Tetrodotoxin Analogs from the Newt, Cynops ensicauda popei, and Comparison of Tetrodotoxin Analogs Profiles of This Newt and the Puffer Fish, Fugu poecilonotus
Yuta Kudo, Takeshi Yasumoto, Keiichi Konoki, Yuko Cho and Mari Yotsu-Yamashita
