© 2017 Published under licence by IOP Publishing Ltd. This study examined the effect of Reynolds number on plasma-assisted flow control ahead of a compression ramp geometry in Mach-2 supersonic flow. The experiments were conducted in the supersonic wind tunnel SBR-50 at the University of Notre Dame. Stagnation temperature and pressure were varied as T0=294-500K and P0=1-3bar to attain Reynolds number ranging from 3.4×105-2.2×106. Ramp pressure measurements, schlieren visualization, and high-speed camera imaging were used for the evaluation of plasma-assisted flow control effects. A linear dependency was found between the ramp pressure change per averaged plasma power and Reynolds number.