Yoshitaka Zaimoku

Profile Information

Affiliation: Assistant professor, Department of Infection Control and Prevention, Kanazawa University Hospital

Degree: 医学博士(Jun, 2017, 金沢大学)

Researcher number: 70895747
ORCID ID: https://orcid.org/0000-0002-4108-5245
J-GLOBAL ID: 202001015600337274
researchmap Member ID: R000011599

Research Interests

Research Areas

Life sciences / Hematology and oncology /

Research History

Apr, 2021 - Present

Assistant Professor, Department of Infection Control and Prevention, Kanazawa University Hospital
Apr, 2020 - Mar, 2021

医員, 血液内科, 金沢大学附属病院
Oct, 2017 - Mar, 2020

Hematology Branch, National Institutes of Health

Education

Apr, 2011 - Jun, 2017

がん医科学, 医学系, 金沢大学大学院
Apr, 2003 - Mar, 2009

Kanazawa University

Awards

2019

第61回米国血液学会学術集会Achievement Award, 米国血液学会

材木義隆
2018

最優秀論文賞（高安賞）, 金沢大学十全医学会

材木義隆
2017

奨励賞, 日本造血細胞移植学会

材木義隆
2016

第58回米国血液学会学術集会Achievement Award, 米国血液学会

材木義隆
2014

第56回米国血液学会学術集会Achievement Award, 米国血液学会

材木義隆
2014

EHA Travel Award, 日本血液学会

材木義隆

Papers

3D CNN-based Deep Learning Model-based Explanatory Prognostication in Patients with Multiple Myeloma using Whole-body MRI

Kento Morita, Shigehiro Karashima, Toshiki Terao, Kotaro Yoshida, Takeshi Yamashita, Takeshi Yoroidaka, Mikoto Tanabe, Tatsuya Imi, Yoshitaka Zaimoku, Akiyo Yoshida …

Journal of Medical Systems, 48(1), Mar 8, 2024
HLA Class I Allele Loss and Bone Marrow Transplantation Outcomes in Immune Aplastic Anemia

Yoshitaka Zaimoku, Takamasa Katagiri, Noriharu Nakagawa, Tatsuya Imi, Hiroyuki Maruyama, Hiroyuki Takamatsu, Ken Ishiyama, Hirohito Yamazaki, Toshihiro Miyamoto, Shinji Nakao

Transplantation and Cellular Therapy, Mar, 2024
Minor GPI(-) granulocyte populations in aplastic anemia and healthy individuals derived from a few PIGA-mutated hematopoietic stem progenitor cells.

Hiroki Mizumaki, Dung Cao Tran, Kohei Hosokawa, Kazuyoshi Hosomichi, Yoshitaka Zaimoku, Hiroyuki Takamatsu, Hirohito Yamazaki, Ken Ishiyama, Rena Yamazaki, Hiroshi Fujiwara …

Blood cancer journal, 13(1) 165-165, Nov 8, 2023
HLA遺伝子型が再生不良性貧血の同種造血細胞移植成績に及ぼす影響 TRUMPデータ解析

材木義隆, 山崎宏人, 金谷穣, 平本展大, 石山謙, 内田直之, 土岐典子, 山本隆介, 西田徹也, 小野寺晃一 …

日本血液学会学術集会, 85回 69-69, Oct, 2023
HLA-B*40:02,A*02:06欠失を伴う免疫性再生不良性貧血の骨髄移植予後は良好である

材木義隆, 片桐孝和, 中川紀温, 井美達也, 丸山裕之, 高松博幸, 石山謙, 山崎宏人, 宮本敏浩, 中尾眞二

日本血液学会学術集会, 85回 1346-1346, Oct, 2023
Correction: Frequent HLA-DR loss on hematopoietic stem progenitor cells in patients with cyclosporine-dependent aplastic anemia carrying HLA-DR15.

Noriaki Tsuji, Kohei Hosokawa, Ryota Urushihara, Mikoto Tanabe, Yoshitaka Zaimoku, Takamasa Katagiri, Tatsuhiko Ozawa, Hiroyuki Takamatsu, Ken Ishiyama, Hirohito Yamazaki …

Leukemia, 37(10) 2143-2143, Oct, 2023
肝炎関連再生不良性貧血におけるHLAクラスIアレル欠失血球の特徴

岩崎寛香, 上森瑞穂, 材木義隆, 細川晃平, 中尾眞二, 片桐孝和

日本血液学会学術集会, 85回 316-316, Oct, 2023
再生不良性貧血におけるシクロスポリン非依存性の寛解には造血幹細胞の進化が必要である

細川晃平, Tran Dung Cao, 水牧裕希, 鎧高健志, 井美達也, 丸山裕之, 辻紀章, 漆原涼太, 田辺命, 材木義隆 …

日本血液学会学術集会, 85回 1347-1347, Oct, 2023
難治性ALK陽性未分化大細胞リンパ腫に対してアレクチニブにより自家移植のブリッジングに成功した一例

村宏樹, 酒井悟臣, 吉野裕貴, 中川紀温, 井美達也, 松浦絵里香, 材木義隆, 細川晃平, 丸山裕之, 吉田晶代 …

日本血液学会学術集会, 85回 1529-1529, Oct, 2023
Comparison of haploidentical stem cell transplantation with post-transplant cyclophosphamide versus umbilical cord blood transplantation in adult patients with aplastic anemia.

Yasushi Onishi, Takehiko Mori, Hirohito Yamazaki, Nobuhiro Hiramoto, Yoshitaka Zaimoku, Minoru Kanaya, Kosei Matsue, Makoto Onizuka, Nobuyuki Aotsuka, Naoyuki Uchida …

Transplantation and cellular therapy, Sep 18, 2023 Peer-reviewed
Familial immune‐mediated aplastic anaemia in six different families

Tatsuya Imi, Hiroki Mizumaki, Kazuyoshi Hosomichi, Yasuhito Nannya, Yoshitaka Zaimoku, Takeshi Yoroidaka, Takamasa Katagiri, Ken Ishiyama, Hirohito Yamazaki, Ryosuke Ogawa …

eJHaem, 4(3) 714-718, Jun 28, 2023 Peer-reviewed
Late graft failure with donor-derived GPI-deficient cells in a mixed chimera following allogeneic bone marrow transplantation for severe aplastic anemia

Hiroo Katsuya, Kyosuke Yamaguchi, Trung Cao Dung, Haruhiko Sano, Hidekazu Itamura, Sho Okamoto, Mariko Yoshimura, Hiroshi Ureshino, Toshihiko Ando, Yoshitaka Zaimoku …

Bone Marrow Transplantation, 58(4) 465-468, Jan 21, 2023 Peer-reviewed
Systematic active environmental surveillance successfully identified and controlled the Legionella contamination in the hospital.

Junya Nakade, Yoko Nakamura, Yusuke Katayama, Hiroyuki Obata, Yoshinori Takahashi, Yoshitaka Zaimoku, Yumi Fujii, Yasunori Iwata

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 29(1) 43-47, Jan, 2023 Peer-reviewed
Predictors of clonal evolution and myeloid neoplasia following immunosuppressive therapy in severe aplastic anemia.

Emma M Groarke, Bhavisha A Patel, Ruba Shalhoub, Fernanda Gutierrez-Rodrigues, Parth Desai, Harshraj Leuva, Yoshitaka Zaimoku, Casey Paton, Nina Spitofsky, Jennifer Lotter …

Leukemia, 36(9) 2328-2337, Sep, 2022 Peer-reviewed
DLBCLに対する化学療法後早期に発症した治療関連AML(M6b)の1例

吉野裕貴, 丸山裕之, 川島隼人, 萩原剛志, 村宏樹, 松浦絵里香, 井美達也, 材木義隆, 細川晃平, 吉田晶代 …

臨床血液, 63(8) 951-951, Aug, 2022 Peer-reviewed
Frequent HLA-DR loss on hematopoietic stem progenitor cells in patients with cyclosporine-dependent aplastic anemia carrying HLA-DR15.

Noriaki Tsuji, Kohei Hosokawa, Ryota Urushihara, Mikoto Tanabe, Yoshitaka Zaimoku, Takamasa Katagiri, Tatsuhiko Ozawa, Hiroyuki Takamatsu, Ken Ishiyama, Hirohito Yamazaki …

Leukemia, 36(6) 1666-1675, Jun, 2022 Peer-reviewed
HLA associations, somatic loss of HLA expression, and clinical outcomes in immune aplastic anemia

Yoshitaka Zaimoku, Bhavisha A. Patel, Sharon D. Adams, Ruba Shalhoub, Emma M. Groarke, Audrey Ai Chin Lee, Sachiko Kajigaya, Xingmin Feng, Olga Julia Rios, Holly Eager …

Blood, 138(26) 2799-2809, Dec 30, 2021 Peer-reviewedLead authorCorresponding author
The effectiveness of immunosuppressive therapy in patients with aplastic anaemia secondary to chemoradiotherapy for cancers

Noriharu Nakagawa, Ken Ishiyama, Mikoto Tanabe, Takeshi Yoroidaka, Hiroki Mizumaki, Tatsuya Imi, Yoshitaka Zaimoku, Hiroyuki Maruyama, Kohei Hosokawa, Hirohito Yamazaki …

British Journal of Haematology, 195(5) 770-780, Dec, 2021 Peer-reviewed
RS3PE症候群を合併した血管免疫芽球性T細胞リンパ腫の1例

東大貴, 畑田達哉, 漆原涼太, 田辺命, 井美達也, 材木義隆, 丸山裕之, 細川晃平, 吉田晶代, 石山謙

臨床血液, 62(10) 1537-1538, Oct, 2021 Peer-reviewed
HLA class I allele-lacking leukocytes predict rare clonal evolution to MDS/AML in patients with acquired aplastic anemia.

Hosokawa K, Mizumaki H, Yoroidaka T, Maruyama H, Imi T, Tsuji N, Urushihara R, Tanabe M, Zaimoku Y, Nguyen MAT …

Blood, 137(25) 3576-3580, Jun 24, 2021 Peer-reviewed

Misc.

再生不良性貧血における新たな免疫逃避機構の同定

辻紀章, 細川晃平, 漆原涼太, 田辺命, 材木義隆, 高松博幸, 石山謙, 山崎宏人, 中尾眞二, 宮本敏浩

日本内科学会雑誌, 112, 2023
HLA Class I Allele-Specific Pathology Defines Clinical Manifestations of Immune Aplastic Anemia

Yoshitaka Zaimoku, Hiroki Mizumaki, Takeshi Yoroidaka, Noriharu Nakagawa, Tatsuya Imi, Hiroyuki Maruyama, Mikoto Tanabe, Noriaki Tsuji, Ryota Urushihara, Kohei Hosokawa …

BLOOD, 140, Nov, 2022
A case of late graft failure with PNH type positive blood cells post transplantation

川島隼人, 丸山裕之, 萩原剛志, 吉野裕貴, 村宏樹, 井美達也, 吉田晶代, 材木義隆, 細川晃平, 高松博幸 …

日本造血・免疫細胞療法学会総会プログラム・抄録集, 45th, 2022
Acute ATLL in which PTCy haplotransplantation was performed with HHV-6 encephalitis treatment

吉野裕貴, 井美達也, 川島隼人, 萩原剛志, 村宏樹, 松浦絵里香, 材木義隆, 細川晃平, 丸山裕之, 吉田晶代 …

日本造血・免疫細胞療法学会総会プログラム・抄録集, 45th, 2022
Two cases of lung cancer that rapidly progressed after allogenic stem cell transplantation

村宏樹, 川島隼人, 吉野裕貴, 萩原剛志, 井美達也, 松浦絵里香, 材木義隆, 細川晃平, 丸山裕之, 吉田晶代 …

日本造血・免疫細胞療法学会総会プログラム・抄録集, 45th, 2022
A case of allogeneic cord blood transplantation for adult-onset chronic active EBV infection

酒井悟臣, 村宏樹, 井美達也, 川島隼人, 萩原剛志, 松浦絵里香, 材木義隆, 丸山裕之, 細川晃平, 吉田昌代 …

日本造血・免疫細胞療法学会総会プログラム・抄録集, 45th, 2022
Progressive pulmonary Aspergillus nodules after auto-PBSCT for refractory DLBCL-a case report

畑田達哉, 材木義隆, 東大貴, 漆原涼太, 田辺命, 井美達也, 丸山裕之, 細川晃平, 吉田晶代, 石山謙 …

日本造血・免疫細胞療法学会総会プログラム・抄録集, 44th, 2022
The Copy Number of Disease-Associated HLA Alleles Predicts the Response to Immunosuppressive Therapy in Acquired Aplastic Anemia

Yoshitaka Zaimoku, Hiroki Mizumaki, Tatsuya Imi, Kohei Hosokawa, Hiroyuki Maruyama, Takamasa Katagiri, Takeshi Yoroidaka, Noriharu Nakagawa, Mikoto Tanabe, Noriaki Tsuji …

BLOOD, 138, Nov, 2021
Successful engraftment of CBT in a case of MDS-EB-1 with donor-specific HLA antibodies

山野塁子, 岩城憲子, 材木義隆, 丸山裕之, 水牧裕希, 石山謙, 中尾眞二

日本造血細胞移植学会総会プログラム・抄録集, 43rd, 2021
The impact of pretransplant cytoreductive chemotherapy on the outcome of HSCT for MDS-EB

丸山裕之, 山野塁子, 田辺命, 高橋稚奈, 井美達也, 材木義隆, 岩城憲子, 高松博幸, 石山謙, 奥村廣和 …

日本造血細胞移植学会総会プログラム・抄録集, 43rd, 2021
CD34⁺ cell doses and engraftment failure: a single institution retrospective study

材木義隆, 石山謙, 佐藤英洋, 山崎宏人, 中尾眞二

日本造血細胞移植学会総会プログラム・抄録集, 43rd, 2021
A case of acute megakaryoblastic leukemia following primary mediastinal germ cell tumor

丸山裕之, 山野塁子, 畑田達哉, 田辺命, 高橋稚奈, 井美達也, 材木義隆, 岩城憲子, 高松博幸, 石山謙 …

日本血液学会学術集会抄録(Web), 83rd, 2021
Recurrent pericarditis induced by cytarabine therapy for acute myeloid leukemia

吉野裕貴, 高橋稚奈, 下島正也, 山野累子, 畑田達哉, 辻紀章, 田辺命, 井美達也, 材木義隆, 丸山裕之 …

日本血液学会学術集会抄録(Web), 83rd, 2021
Markedly high prevalence of HLA-lacking leukocytes in patients with very severe aplastic anemia

井美達也, 漆原涼太, 辻紀章, 田辺命, 水牧裕希, 材木義隆, 細川晃平, 高松博幸, 石山謙, 山崎宏人 …

日本血液学会学術集会抄録(Web), 83rd, 2021
Uncontrollable bleeding associated with marked leukocytosis due to CML in CP at presentation

畑田達哉, 岩城憲子, 山野塁子, 材木義隆, 丸山裕之, 井美達也, 細川晃平, 高松博幸, 石山謙, 中尾眞二

日本血液学会学術集会抄録(Web), 83rd, 2021
Frequencies and clinical significance of HLA alleles in acquired aplastic anemia

材木義隆, 細川晃平, 片桐孝和, 丸山裕之, 井美達也, 水牧裕希, 鎧高健志, 田辺命, 漆原涼太, 辻紀章 …

日本血液学会学術集会抄録(Web), 83rd, 2021
Clinical usefulness of repeat blood cultures in febrile patients

漆原涼太, 材木義隆, 大谷初美, 石山謙, 中尾眞二

日本血液学会学術集会抄録(Web), 83rd, 2021
Additional chemotherapy and DLI after PTCy haplo-SCT improved the survival of two refractory myeloma

井美達也, 高松博幸, 萩原剛志, 田辺命, 高橋稚奈, 山野塁子, 材木義隆, 丸山裕之, 岩城憲子, 細川晃平 …

日本造血細胞移植学会総会プログラム・抄録集, 43rd, 2021
Outcome of allogeneic hematopoietic stem cell transplantation for 25 cases of aplastic anemia

高橋稚奈, 山野塁子, 田辺命, 材木義隆, 丸山裕之, 井美達也, 細川晃平, 岩城憲子, 高松博幸, 石山謙 …

日本造血細胞移植学会総会プログラム・抄録集, 43rd, 2021
Clonal Hematopoiesis By HLA Class I Allele-Lacking Hematopoietic Stem Cells and Concomitant Aberrant Stem Cells Is Rarely Associated with Clonal Evolution to Secondary Myelodysplastic Syndrome and Acute Myeloid Leukemia in Patients with Acquired Aplastic Anemia

Kohei Hosokawa, Hiroki Mizumaki, Takeshi Yoroidaka, Hiroyuki Maruyama, Tatsuya Imi, Noriaki Tsuji, Ryota Urushihara, Mikoto Tanabe, Yoshitaka Zaimoku, Mai Anh Thi Nguyen …

BLOOD, 136, Nov, 2020

Presentations

HLA Class I Genotypes Predict the Survival after Hematopoietic Stem Cell Transplantation in Immune Aplastic Anemia

Yoshitaka Zaimoku, Hirohito Yamazaki, Minoru Kanaya, Nobuhiro Hiramoto, Ken Ishiyama, Naoyuki Uchida, Noriko Doki, Ryusuke Yamamoto, Tetsuya Nishida, Koichi Onodera, Shinichiro Machid, Yoshinobu Kanda, Tetsuya Eto, Fumihiko Ishimaru, Makoto Onizuka, Tatsuo Ichinohe, Yoshiko Atsuta, Yasushi Onishi

65TH ASH ANNUAL MEETING AND EXPOSITION, Dec 11, 2023
Prevalence and Outcome of Vexas Syndrome in Unrelated Hematopoietic Stem Cell Transplantation

Yoshitaka Zaimoku, Tatsuya Imi, Tatsuya Hatada, Hiroki Mura, Hiroki Yoshino, Dung Cao Tran, Yasuhito Nannya, Seishi Ogawa, Kazuyoshi Hosomichi, Noriko Doki, Yuta Katayama, Takashi Koike, Ken-ichi Matsuoka, Tetsuya Nishida, Yoshiyuki Takahashi, Keisuke Kataoka, Hideyuki Nakazawa, Yasunori Ueda, Takahiro Fukuda, Tatsuo Ichinohe, Fumihiko Ishimaru, Makoto Onizuka, Yoshiko Atsuta, Toshihiro Miyamoto

65TH ASH ANNUAL MEETING AND EXPOSITION, Dec 9, 2023
HLA Class I Allele-Specific Pathology Defines Clinical Manifestations of Immune Aplastic Anemia

Yoshitaka Zaimoku, Hiroki Mizumaki, Takeshi Yoroidaka, Noriharu Nakagawa, Tatsuya Imi, Hiroyuki Maruyama, Mikoto Tanabe, Noriaki Tsuji, Ryota Urushihara, Kohei Hosokawa, Takamasa Katagiri, Hiroyuki Takamatsu, Ken Ishiyama, Hirohito Yamazaki, Toshihiro Miyamoto, Shinji Nakao

64th ASH Annual Meeting and Exposition, Dec 10, 2022
Role of HLA in AA

Yoshitaka Zaimoku

8th International Bone Marrow Failure Disease Scientific Symposium, May 19, 2022 Invited
The Copy Number of Disease-Associated HLA Alleles Predicts the Response to Immunosuppressive Therapy in Acquired Aplastic Anemia

Yoshitaka Zaimoku, Hiroki Mizumaki, Tatsuya Imi, Kohei Hosokawa, Hiroyuki Maruyama, Takamasa Katagiri, Takeshi Yoroidaka, Noriharu Nakagawa, Mikoto Tanabe, Noriaki Tsuji, Ryota Urushihara, Hiroyuki Takamatsu, Hirohito Yamazaki, Ken Ishiyama, Shinji Nakao

63rd ASH Annual Meeting and Exposition, Dec 13, 2021
Spectrum and Clinical Significance of HLA Class I Alleles and their Somatic Mutations in Immune Aplastic Anemia

Zaimoku Y, Adams SD, Patel BA, Lee AAC, Kajigaya S, Feng X, Rios O, DiFebo H, Alemu L, Quinones Raffo D, Groarke EM, Flegel WA, Young NS

61st ASH Annual Meeting and Exposition. San Diego, CA, USA, Dec 9, 2019
Deficit of Circulating CD19+CD24hiCD38hi Regulatory B Cells in Severe Aplastic Anemia

Zaimoku Y, Patel BA, Kajigaya S, Feng X, Alemu L, Quinones Raffo D, Groarke EM, Young NS

61st ASH Annual Meeting and Exposition. San Diego, CA, USA, Dec 7, 2019
Identification of an HLA class I allele closely involved in the pathogenesis of acquired aplastic anemia

Zaimoku Y, Takamatsu H, Hosomichi K, Ozawa T, Nakagawa N, Imi T, Kishi H, Kashiwase K, Nakao S

58th ASH Annual Meeting and Exposition. San Diego, CA, USA., Dec 5, 2016
Identification of an HLA class I allele that is closely involved in the auto-antigen presentation by hematopoietic stem cells to T cells in acquired aplastic anemia.

Zaimoku Y, Takamatsu H, Nakagawa N, Imi T, Hosomichi K, Nakao S

5th International Bone Marrow Failure Disease Scientific Symposium. Rockville, MD, USA, Mar 17, 2016
Clonal dynamics of human hematopoiesis deduced from escape hematopoiesis of patients with acquired aplastic anemia

Zaimoku Y

2015 International Symposium: Leading Innovation in Immunology, Hematology, Oncology and Stem Cell Biology. Kanazawa, Japan., Feb 13, 2015 Invited
Donor-type aplastic anemia after HSCT: a common cause of late graft failure in patients with complete donor chimerism

Zaimoku Y, Maruyama K, Maruyama H, Katagiri T, Yamazaki H, Nakao S

19th Winter Scientific Meeting of the Korean Society of Blood and Marrow Transplantation. Pyengchang, Korea., Feb 6, 2015 Invited
Evidence that HLA-B*40:02 and HLA-Α*31:01 are strongly involved in the presentation of autoantigens to CTLs responsible for the development of acquired aplastic anemia

Zaimoku Y, Maruyama H, Maruyama K, Katagiri T, Dao AT, Takamatsu H, Yamazaki H, Kashiwase K, Nakao S

56th ASH Annual Meeting and Exposition. San Francisco, CA, USA., Dec 7, 2014

Professional Memberships

May, 2022 - Present

American Society of Hematology
2021 - Present

日本感染症学会
2021 - Present

日本輸血・細胞治療学会
2011 - Present

日本造血細胞移植学会
2011 - Present

日本血液学会
2011 - Present

日本内科学会

Research Projects

再生不良性貧血における７番染色体欠失クローン進展機序の解明

科学研究費助成事業, 若手研究, 日本学術振興会, Apr, 2021 - Mar, 2023

材木義隆

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