Research Projects

Apr, 2014 - Mar, 2018

Clarification of the tumor microenvironment in the development of urothelial carcinoma using animal model

Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B)  Grant-in-Aid for Scientific Research (B)
  • Nishiyama Hiroyuki

Grant number
26293349
Japan Grant Number (JGN)
JP26293349
Grant amount
(Total)
15,860,000 Japanese Yen
(Direct funding)
12,200,000 Japanese Yen
(Indirect funding)
3,660,000 Japanese Yen

We tested that guinea pigs can have bladder cancer by orally ingesting bracken. As a result of HE staining and immunostaining of the tumor of the bladder in the guinea pigs, it was confirmed that the tumor were non-muscle invaseve bladdere tumora. Guinea pigs have the same CD1b as human for lipid immunity. CD1b is a receptor for mycolic acid and we believe that future use of this bladder cancer cell line will elucidate the involvement of lipid immunity and T cell immunity.

Link information
Kaken Url
https://kaken.nii.ac.jp/file/KAKENHI-PROJECT-26293349/26293349seika.pdf
KAKEN
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-26293349
ID information
  • Grant number : 26293349
  • Japan Grant Number (JGN) : JP26293349