Apr, 2014 - Mar, 2018
Clarification of the tumor microenvironment in the development of urothelial carcinoma using animal model
Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B) Grant-in-Aid for Scientific Research (B)
- Grant number
- 26293349
- Japan Grant Number (JGN)
- JP26293349
- Grant amount
-
- (Total)
- 15,860,000 Japanese Yen
- (Direct funding)
- 12,200,000 Japanese Yen
- (Indirect funding)
- 3,660,000 Japanese Yen
We tested that guinea pigs can have bladder cancer by orally ingesting bracken. As a result of HE staining and immunostaining of the tumor of the bladder in the guinea pigs, it was confirmed that the tumor were non-muscle invaseve bladdere tumora. Guinea pigs have the same CD1b as human for lipid immunity. CD1b is a receptor for mycolic acid and we believe that future use of this bladder cancer cell line will elucidate the involvement of lipid immunity and T cell immunity.
- Link information
- ID information
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- Grant number : 26293349
- Japan Grant Number (JGN) : JP26293349