1995年3月
SYNTHESIS AND BIOLOGICAL-ACTIVITIES OF NEW CONFORMATIONALLY FIXED ANALOGS OF (-)-INDOLACTAM-V, THE CORE STRUCTURE OF TUMOR-PROMOTING TELEOCIDINS
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
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- 巻
- 5
- 号
- 5
- 開始ページ
- 453
- 終了ページ
- 458
- 記述言語
- 英語
- 掲載種別
- 研究論文（学術雑誌）
- DOI
- 10.1016/0960-894X(95)00047-W
- 出版者・発行元
- PERGAMON-ELSEVIER SCIENCE LTD
(-)-Indolactam-V(1) exists as two stable conformers, the twist and the sofa form, in solution at room temperature. 3-Aza-Cope rearrangement of (-)-N-13-desmethyl-N-13-allylindolactam-V (5) gave new conformationally restricted analogues (2a and 3) along with a normal rearrangement product (7). Both 2a and 3, whose fixed conformation was the twist form, showed significant biological activities related to tumor promotion.
- リンク情報
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- DOI
- https://doi.org/10.1016/0960-894X(95)00047-W
- Web of Science
- https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:A1995QM74100007&DestApp=WOS_CPL
- URL
- https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0028935575&origin=inward
- ID情報
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- DOI : 10.1016/0960-894X(95)00047-W
- ISSN : 0960-894X
- SCOPUS ID : 0028935575
- Web of Science ID : WOS:A1995QM74100007