2010年
Programmed-Assembly System Using DNA Jigsaw Pieces
CHEMISTRY-A EUROPEAN JOURNAL
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- 巻
- 16
- 号
- 18
- 開始ページ
- 5362
- 終了ページ
- 5368
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1002/chem.200903057
- 出版者・発行元
- WILEY-V C H VERLAG GMBH
A novel method for assembling multiple DNA origami structures has been developed by using designed 2D DNA origami rectangles, so-called "DNA jigsaw pieces" that have sequence-programmed connectors. Shape and sequence complementarity were introduced to the concavity and convex connectors in the DNA rectangles for selective connection with the help of nonselective pi-stacking interactions between the side edges of the DNA jigsaw piece structures. Single DNA jigsaw piece units were assembled into unidirectional nanostructures with the correct alignment and uniform orientation. Three and five different DNA jigsaw pieces were assembled into pre-designed and ordered nanostructures in a programmed fashion. Finally, three-, four-, and five-letter words have been displayed by using this programmed DNA jigsaw piece system.
- リンク情報
- ID情報
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- DOI : 10.1002/chem.200903057
- ISSN : 0947-6539
- PubMed ID : 20391568
- Web of Science ID : WOS:000277988900016