2000年1月1日
Recent advances in the study of the biosynthesis and functions of sulfated glycosaminoglycans
Current Opinion in Structural Biology
- ,
- 巻
- 10
- 号
- 開始ページ
- 518
- 終了ページ
- 527
- DOI
- 10.1016/S0959-440X(00)00125-1
Recent cDNA cloning of the glycosyltransferases involved in the synthesis of the sulfated glycosaminoglycan sidechains of proteoglycans has provided important clues to answering long-standing questions concerning the mechanisms of both chain polymerization and the biosynthetic sorting of glucosaminoglycans (heparin/heparan sulfate) and galactosaminoglycans (chondroitin/dermatan sulfate). These biosynthetic mechanisms are crucial to the expression and regulation of the biological functions of glycosaminoglycans in development and pathophysiology.
- リンク情報
- ID情報
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- DOI : 10.1016/S0959-440X(00)00125-1
- ISSN : 0959-440X
- PubMed ID : 11042448
- SCOPUS ID : 0033794318