Itoh Go

Profile Information

Affiliation: -

Researcher number: 60607563
J-GLOBAL ID: 201801013984884454
researchmap Member ID: B000343763

Research Interests

Research Areas

Research History

2014 - Present

Graduate School of Medicine, Akita University
2011 - 2014

Institute of Development, Aging and Cancer, Tohoku University
2008 - 2011

Institute of Development, Aging and Cancer, Tohoku University
2004 - 2008

修了（Ph.D.）, 山口大学大学院博士後期課程

Awards

Papers

Exosomes secreted by ST3GAL5high cancer cells promote peritoneal dissemination by establishing a pre-metastatic microenvironment.

Misato Horie, Kurara Takagane, Go Itoh, Sei Kuriyama, Kazuyoshi Yanagihara, Masakazu Yashiro, Michinobu Umakoshi, Akiteru Goto, Junichi Arita, Masamitsu Tanaka

Molecular oncology, Sep 16, 2023
CCDC85A is regulated by miR-224-3p and augments cancer cell resistance to endoplasmic reticulum stress.

So Takahashi, Kurara Takagane, Go Itoh, Sei Kuriyama, Michinobu Umakoshi, Akiteru Goto, Kazuyoshi Yanagihara, Masakazu Yashiro, Katsunori Iijima, Masamitsu Tanaka

Frontiers in oncology, 13 1196546-1196546, 2023
Dynamics of Actin Cytoskeleton and Their Signaling Pathways during Cellular Wound Repair.

Shigehiko Yumura, Md Shahabe Uddin Talukder, Mst Shaela Pervin, Md Istiaq Obaidi Tanvir, Takashi Matsumura, Koushiro Fujimoto, Masahito Tanaka, Go Itoh

Cells, 11(19), Oct 9, 2022 Peer-reviewed
Pigment Epithelium Derived Factor is involved in the late phase of osteosarcoma metastasis by increasing extravasation and cell-cell adhesion.

Sei Kuriyama, Gentaro Tanaka, Kurara Takagane, Go Itoh, Masamitsu Tanaka

Frontiers in Oncology, 12 818182-818182, Jan 31, 2022 Peer-reviewed
SKAP2 suppresses inflammation-mediated tumorigenesis by regulating SHP-1 and SHP-2.

Kurara Takagane, Michinobu Umakoshi, Go Itoh, Sei Kuriyama, Akiteru Goto, Masamitsu Tanaka

Oncogene, Jan 17, 2022 Peer-reviewed
Cancer-associated fibroblasts educate normal fibroblasts to facilitate cancer cell spreading and T cell suppression.

Go Itoh, Kurara Takagane, Yuma Fukushi, Sei Kuriyama, Michinobu Umakoshi, Akiteru Goto, Kazuyoshi Yanagihara, Masakazu Yashiro, Masamitsu Tanaka

Molecular Oncology, 16(1) 166-187, Jan 16, 2022 Peer-reviewed
Chromosome alignment-maintaining phosphoprotein CHAMP1 plays a role in cell survival through regulating Mcl-1 expression.

Maho Hino, Kenji Iemura, Masanori Ikeda, Go Itoh, Kozo Tanaka

Cancer Science, 111(9) 3711-3721, Jun 9, 2021 Peer-reviewed
Dynamics of Myosin II Filaments during Wound Repair in Dividing Cells.

Md Istiaq Obaidi Tanvir, Go Itoh, Hiroyuki Adachi, Shigehiko Yumura

Cells, 10(5), May 17, 2021 Peer-reviewed
Expression of asporin reprograms cancer cells to acquire resistance to oxidative stress.

Yuto Sasaki, Kurara Takagane, Takumi Konno, Go Itoh, Sei Kuriyama, Kazuyoshi Yanagihara, Masakazu Yashiro, Satoru Yamada, Shinya Murakami, Masamitsu Tanaka

Cancer Science, 112(3) 1251-1261, Mar, 2021 Peer-reviewed
Ca2+-Calmodulin Dependent Wound Repair in Dictyostelium Cell Membrane.

Md Shahabe Uddin Talukder, Mst Shaela Pervin, Md Istiaq Obaidi Tanvir, Koushiro Fujimoto, Masahito Tanaka, Go Itoh, Shigehiko Yumura

Cells, 9(4), Apr 23, 2020 Peer-reviewed
Dynamin-Like Protein B of Dictyostelium Contributes to Cytokinesis Cooperatively with Other Dynamins.

Fujimoto K, Tanaka M, Rana AYKMM, Jahan MGS, Go Itoh, Tsujioka M, Uyeda TQP, Miyagishima SY, Yumura S

Cells, 8(8), Jul, 2019 Peer-reviewed
Macrophage-mediated transfer of cancer-derived components to stromal cells contributes to establishment of a pro-tumor microenvironment.

Michinobu Umakoshi, So Takahashi, Go Itoh, Sei Kuriyama, Yuto Sasaki, Kazuyoshi Yanagihara, Masakazu Yashiro, Daichi Maeda, Akiteru Goto, Masamitsu Tanaka

Oncogene, 38(12) 2162-2176, Mar, 2019 Peer-reviewed
Lateral attachment of kinetochores to microtubules is enriched in prometaphase rosette and facilitates chromosome alignment and bi-orientation establishment

Go Itoh, Masanori Ikeda, Kenji Iemura, Mohammed Abdhullahel Amin, Sei Kuriyama, Masamitsu Tanaka, Natsuki Mizuno, Hiroko Osakada, Tokuko Haraguchi, Kozo Tanaka

Scientific Reports, 8(1) 3888, Dec 1, 2018 Peer-reviewed
A study of wound repair in Dictyostelium cells by using novel laserporation.

Mst Shaela Pervin, Go Itoh, Md Shahabe Uddin Talukder, Koushiro Fujimoto, Yusuke V Morimoto, Masamitsu Tanaka, Masahiro Ueda, Shigehiko Yumura

Scientific Reports, 8(1) 7969-7969, May 22, 2018 Peer-reviewed
Cancer-associated fibroblasts induce cancer cell apoptosis that regulates invasion mode of tumours

Go Itoh, Shinsuke Chida, Kazuyoshi Yanagihara, Masakazu Yashiro, Namiko Aiba, Masamitsu Tanaka

Oncogene, 36(31) 4434-4444, Aug, 2017 Peer-reviewed
Mesothelial Cells Create a Novel Tissue Niche That Facilitates Gastric Cancer Invasion

Masamitsu Tanaka, Sei Kuriyama, Go Itoh, Daichi Maeda, Akiteru Goto, Yutaro Tamiya, Kazuyoshi Yanagihara, Masakazu Yashiro, Namiko Aiba

Cancer Research, 77(3) 684-695, Feb, 2017 Peer-reviewed
Identification of anti-cancer chemical compounds using Xenopus embryos

Masamitsu Tanaka, Sei Kuriyama, Go Itoh, Aki Kohyama, Yoshiharu Iwabuchi, Hiroyuki Shibata, Masakazu Yashiro, Namiko Aiba

Cancer Science, 107(6) 803-811, Jun, 2016 Peer-reviewed
CLIP-170 recruits PLK1 to kinetochores during early mitosis for chromosome alignment

Mohammed Abdullahel Amin, Go Itoh, Kenji Iemura, Masanori Ikeda, Kozo Tanaka

Journal of Cell Science, 127(13) 2818-2824, Jul, 2014 Peer-reviewed
Nucleoporin Nup188 is required for chromosome alignment in mitosis

Go Itoh, Shiro Sugino, Masanori Ikeda, Mayumi Mizuguchi, Shin-ichiro Kanno, Amin Mohammed A, Kenji Iemura, Akira Yasui, Toru Hirota, Kozo Tanaka

Cancer Science, 104(7) 871-879, Jul, 2013 Peer-reviewed
Cell-scale dynamic recycling and cortical flow of the actin-myosin cytoskeleton for rapid cell migration

Shigehiko Yumura, Go Itoh, Yumi Kikuta, Takeomi Kikuchi, Toshiko Kitanishi-Yumura, Masatsune Tsujioka

Biology Open, 2(2) 200-209, Feb, 2013 Peer-reviewed

Misc.

Exosomes of ST3G5^high cancer cells promote pre-metastatic niche of peritoneal dissemination

田中正光, 堀江美里, 高金くらら, 伊藤剛, 栗山正, 柳原五吉, 八代正和

日本癌学会学術総会抄録集(Web), 82nd, 2023
線維芽細胞による腫瘍進展システム

伊藤剛, 高金くらら, 福士由真, 栗山正, 田中正光

Precision Medicine., 4(14), 2021 Invited
Mechanmisms for determing a disseminated and expansive cancer invasion.

Itoh G, Tanaka Masamitsu

Seikagaku., 2018 Invited
Cancer-stromal cells response controlled by death vesicles.

Itoh G, Tanaka Masamitsu

Akita J Med., 2018 Invited
CAMP is required for cell survival during mitotic arrest by anti-mitotic drugs)

家村顕自, 伊藤剛, 田中耕三

日本癌学会総会記事., 73回 J-3002, 2014

Teaching Experience

Professional Memberships

Research Projects

遠隔間質ニッチの形成による癌の拡散メカニズム

科学研究費助成事業, 基盤研究(B), 日本学術振興会, Apr, 2022 - Mar, 2025

田中正光, 栗山正, 伊藤剛
がん間質の細胞間応答が癌再燃ニッチ構築に与えるインパクト

東北大学加齢医学研究所令和5年度加齢研共同研究, Apr, 2023 - Mar, 2024

伊藤剛
間質細胞による癌細胞分裂の制御メカニズムの解明

基盤研究 (C), 日本学術振興会, 2022 - 2024

伊藤剛
癌の悪性化につながる間質細胞の細胞間マルチプル・ネットワークの創生と解析

2020年度医学系研究助成（がん領域・基礎）, 武田化学振興財団, Oct, 2020 - Oct, 2023

伊藤剛
巨核・多核癌細胞が与えるがん微小環境へのインパクト

令和3年度医学系研究科長による先端研究助成金, 秋田大学, Feb, 2021 - Feb, 2023

伊藤剛
Macrophage-mediated transfer of cancer-derived components to stromal cells creates a pro-tumor microenvironment

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2019 - Mar, 2022

Tanaka Masamitsu
がん微小環境が癌ゲノム情報の多様性を創生するメカニズムの解明

令和3年度加齢研共同研究, 東北大学加齢医学研究所, Apr, 2021 - Mar, 2022

伊藤剛
Dynamics of GMN cancer cells: Synergistic effect on cancer malignant alteration by CAF

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2019 - 2021

Itoh Go
癌細胞のデス小胞が惹起する新規なCAFリード型の癌浸潤プロセスの解明

若手研究 (B), 日本学術振興会, 2017 - 2018

伊藤剛
Analysis of Cancer cell death induced by "Death-touch"

Grants-in-Aid for Scientific Research, Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, Apr, 2014 - Mar, 2017

Tanaka Masamitsu, KURIYAMA SEI, ITOH GO
Elucidating chromosomal instability by chromosome tracking in live cell imaging

Grants-in-Aid for Scientific Research, Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, Apr, 2014 - Mar, 2016

Tanaka Kozo, ITOH GO, IKEDA MASANORI
Mechanisms of cancer guidance and elimination by stromal cells

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2013 - Mar, 2016

Tanaka Masamitsu, KURIYAMA SEI, ITOH GO
Regulatory system of chromosomal stability by molecules including a novel molecule, CAMP

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2012 - Mar, 2015

TANAKA Kozo, ITOH Go, HIROTA Toru, YASUI Akira, KANNO Shin-ichiro
核膜孔複合体構成因子による染色体分配の制御機構と染色体不安定性との関連

若手研究 (B), 日本学術振興会, 2014 - 2015

伊藤剛
Basic research to overcome resistance to anti-mitotic drugs

Grants-in-Aid for Scientific Research, Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, Apr, 2012 - Mar, 2014

TANAKA Kozo, ITOH Go, HIROTA Toru, YASUI Akira, KANNO Shinichiro
新規分子CAMPが分裂期の染色体整列を維持させる分子機構の解明

研究活動スタート支援, 日本学術振興会, 2011 - 2012

伊藤剛
Molecular network supporting chromosomal stability

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2009 - 2011

TANAKA Kozo, YASUI Akira, ITOH Go, KANNO Shinichiro, TANAKA Tomoyuki

Profile Information

Research Interests

Research Areas

Research History

Awards

Papers

Misc.

Teaching Experience

Professional Memberships

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