Souta Motoike

Profile Information

Affiliation: Kyoto University

Researcher number: 80881292
J-GLOBAL ID: 202001015362233716
researchmap Member ID: R000001834

Research Areas

Research History

Apr, 2021 - Present

日本学術振興会特別研究員(PD), 京都大学iPS細胞研究所
Apr, 2020 - Mar, 2021

広島大学病院歯周診療科歯科診療医
Apr, 2018 - Mar, 2020

Japan Society for the Promotion of Science

Education

Apr, 2016 - Mar, 2020

広島大学大学院医歯薬保健学研究科歯周病態学研究室
Apr, 2009 - Mar, 2015

Faculty of Dentistry, Hiroshima University

Awards

Papers

Mechanosignaling YAP/TAZ-TEAD Axis Regulates the Immunomodulatory Properties of Mesenchymal Stem Cells.

Hiroki Yoshii, Mikihito Kajiya, Mai Yoshino, Shin Morimoto, Susumu Horikoshi, Misako Tari, Souta Motoike, Tomoyuki Iwata, Kazuhisa Ouhara, Toshinori Ando …

Stem cell reviews and reports, Nov 2, 2023
A Cartilaginous Construct with Bone Collar Exerts Bone-Regenerative Property Via Rapid Endochondral Ossification

Shin Morimoto, Mikihito Kajiya, Hiroki Yoshii, Mai Yoshino, Susumu Horikoshi, Souta Motoike, Tomoyuki Iwata, Kazuhisa Ouhara, Toshinori Ando, Tetsuya Yoshimoto …

Stem Cell Reviews and Reports, May 11, 2023
Induction of functional xeno-free MSCs from human iPSCs via a neural crest cell lineage

Daisuke Kamiya, Nana Takenaka-Ninagawa, Souta Motoike, Mikihito Kajiya, Teppei Akaboshi, Chengzhu Zhao, Mitsuaki Shibata, Sho Senda, Yayoi Toyooka, Hidetoshi Sakurai …

npj Regenerative Medicine, 7(1), Sep 15, 2022
Clumps of mesenchymal stem cells/extracellular matrix complexes directly reconstruct the functional periodontal tissue in a rat periodontal defect model.

Hisakatsu Sone, Mikihito Kajiya, Katsuhiro Takeda, Shinya Sasaki, Susumu Horikoshi, Souta Motoike, Shin Morimoto, Hiroki Yoshii, Mai Yoshino, Tomoyuki Iwata …

Journal of tissue engineering and regenerative medicine, Aug 11, 2022
Xenotransplantation of cryopreserved human clumps of mesenchymal stem cells/extracellular matrix complexes pretreated with IFN-γ induces rat calvarial bone regeneration

Tomoya Ogawa, Mikihito Kajiya, Susumu Horikoshi, Hiroki Yoshii, Mai Yoshino, Souta Motoike, Shin Morimoto, Hisakatsu Sone, Tomoyuki Iwata, Kazuhisa Ouhara …

Regenerative Therapy, 20 117-125, Jun, 2022
Clumps of Mesenchymal Stem Cells/Extracellular Matrix Complexes Generated with Xeno-Free Chondro-Inductive Medium Induce Bone Regeneration via Endochondral Ossification.

Susumu Horikoshi, Mikihito Kajiya, Souta Motoike, Mai Yoshino, Shin Morimoto, Hiroki Yoshii, Tomoya Ogawa, Hisakatsu Sone, Tomoyuki Iwata, Kazuhisa Ouhara …

Biomedicines, 9(10), Oct 7, 2021
Cox2-mediated PGE2 production via p38/JNK-c-fos signaling inhibits cell apoptosis in 3D floating culture clumps of mesenchymal stem cell/extracellular matrix complexes

Nao Komatsu, Mikihito Kajiya, Shin Morimoto, Souta Motoike, Hiroki Yoshii, Tomoyuki Iwata, Kazuhisa Ouhara, Shinji Matsuda, Noriyoshi Mizuno, Hidemi Kurihara

Biochemical and Biophysical Research Communications, Jun, 2020 Peer-reviewed
Clumps of Mesenchymal Stem Cell/Extracellular Matrix Complexes Generated with Xeno-Free Conditions Facilitate Bone Regeneration via Direct and Indirect Osteogenesis.

Souta Motoike, Mikihito Kajiya, Nao Komatsu, Susumu Horikoshi, Tomoya Ogawa, Hisakatsu Sone, Shinji Matsuda, Kazuhisa Ouhara, Tomoyuki Iwata, Noriyoshi Mizuno …

International journal of molecular sciences, 20(16), Aug 15, 2019 Peer-reviewed
Type I collagen deposition via osteoinduction ameliorates YAP/TAZ activity in 3D floating culture clumps of mesenchymal stem cell/extracellular matrix complexes.

Nao Komatsu, Mikihito Kajiya, Souta Motoike, Manabu Takewaki, Susumu Horikoshi, Tomoyuki Iwata, Kazuhisa Ouhara, Katsuhiro Takeda, Shinji Matsuda, Tsuyoshi Fujita …

Stem cell research & therapy, 9(1) 342-342, Dec 7, 2018 Peer-reviewed
Cryopreserved clumps of mesenchymal stem cell/extracellular matrix complexes retain osteogenic capacity and induce bone regeneration.

Souta Motoike, Mikihito Kajiya, Nao Komatsu, Manabu Takewaki, Susumu Horikoshi, Shinji Matsuda, Kazuhisa Ouhara, Tomoyuki Iwata, Katsuhiro Takeda, Tsuyoshi Fujita …

Stem cell research & therapy, 9(1) 73-73, Mar 21, 2018 Peer-reviewed
MSC/ECM Cellular Complexes Induce Periodontal Tissue Regeneration.

M Takewaki, M Kajiya, K Takeda, S Sasaki, S Motoike, N Komatsu, S Matsuda, K Ouhara, N Mizuno, T Fujita …

Journal of dental research, 96(9) 984-991, Aug, 2017 Peer-reviewed
Xenotransplantation of interferon-gamma-pretreated clumps of a human mesenchymal stem cell/extracellular matrix complex induces mouse calvarial bone regeneration.

Kei Takeshita, Souta Motoike, Mikihito Kajiya, Nao Komatsu, Manabu Takewaki, Kazuhisa Ouhara, Tomoyuki Iwata, Katsuhiro Takeda, Noriyoshi Mizuno, Tsuyoshi Fujita …

Stem cell research & therapy, 8(1) 101-101, Apr 26, 2017 Peer-reviewed

Professional Memberships

Research Projects

神経堤細胞を用いた顎骨オルガノイドの創成

科学研究費助成事業特別研究員奨励費, 特別研究員奨励費, 日本学術振興会, Apr, 2021 - Mar, 2024

本池総太
大規模歯周組織欠損の再生を目指した神経堤細胞由来骨/軟骨複合型オルガノイドの創成

科学研究費助成事業若手研究, 若手研究, 日本学術振興会, Apr, 2021 - Mar, 2023

本池総太
神経堤細胞由来顎骨オルガノイドを用いたMRONJの病態解析及び創薬研究

科学研究費助成事業研究活動スタート支援, 研究活動スタート支援, 日本学術振興会, Sep, 2020 - Mar, 2022

本池総太
三次元間葉系幹細胞集塊を細胞製剤として応用する新規歯周組織再生療法開発

科学研究費助成事業特別研究員奨励費, 特別研究員奨励費, 日本学術振興会, Apr, 2018 - Mar, 2020

本池総太

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