松沢厚 (atsushi matsuzawa) - マイポータル

基本情報

所属: 東北大学薬学研究科教授

学位: 博士（薬学）(東京大学)

J-GLOBAL ID: 200901051352042791
researchmap会員ID: 5000046232

外部リンク: http://www.pharm.tohoku.ac.jp/~eisei/eisei.HP/index.html

研究キーワード

研究分野

経歴

受賞

論文

109

The NLRP3 Inflammasome Is a Major Cause of Acute Renal Failure Induced by Polypeptide Antibiotics

Tomohiro Kagi, Aya Inoue, Takuya Noguchi, Wakana Suzuki, Saya Takano, Kohei Otani, Rio Naganuma, Yuto Sekiguchi, Yusuke Hirata, Sawako Shindo …

The Journal of Immunology 2024年4月19日査読有り最終著者責任著者
The E3 Ubiquitin Protein Ligase LINCR Amplifies the TLR-Mediated Signals through Direct Degradation of MKP1

Takumi Yokosawa, Sayoko Miyagawa, Wakana Suzuki, Yuki Nada, Yusuke Hirata, Takuya Noguchi, Atsushi Matsuzawa

Cells 13(8) 687-687 2024年4月15日査読有り最終著者責任著者
Aggregability of the SQSTM1/p62-based aggresome-like induced structures determines the sensitivity to parthanatos

Shuhei Hamano, Takuya Noguchi, Yukino Asai, Ryo Ito, Ryuto Komatsu, Tetsu Sato, Aya Inoue, Tomoe Maruyama, Tada-aki Kudo, Yusuke Hirata …

Cell Death Discovery 10(1) 2024年2月12日査読有り最終著者責任著者
Physical Stimulation Methods Developed for In Vitro Neuronal Differentiation Studies of PC12 Cells: A Comprehensive Review

Kanako Tominami, Tada-aki Kudo, Takuya Noguchi, Yohei Hayashi, You-Ran Luo, Takakuni Tanaka, Ayumu Matsushita, Satoshi Izumi, Hajime Sato, Keiko Gengyo-Ando …

International Journal of Molecular Sciences 25(2) 772-772 2024年1月7日査読有り
Industrially produced <i>trans</i>-fatty acids are potent promoters of DNA damage-induced apoptosis

Yusuke Hirata, Ryota Kojima, Ryo Ashida, Yuki Nada, Shinnosuke Kimura, Emiko Sato, Takuya Noguchi, Atsushi Matsuzawa

The Journal of Toxicological Sciences 49(1) 27-36 2024年査読有り最終著者責任著者
LLPS of SQSTM1/p62 and NBR1 as outcomes of lysosomal stress response limits cancer cell metastasis

Takuya Noguchi, Yuto Sekiguchi, Tatsuya Shimada, Wakana Suzuki, Takumi Yokosawa, Tamaki Itoh, Mayuka Yamada, Midori Suzuki, Reon Kurokawa, Yusuke Hirata …

PNAS 120(43) e2311282120 2023年10月査読有り最終著者責任著者
Methylmercury directly modifies the 105th cysteine residue in oncostatin M to promote binding to tumor necrosis factor receptor 3 and inhibit cell growth.

Takashi Toyama, Sidi Xu, Yoshitomi Kanemitsu, Takashi Hasegawa, Takuya Noguchi, Jin-Yong Lee, Atsushi Matsuzawa, Akira Naganuma, Gi-Wook Hwang

Archives of toxicology 2023年5月17日査読有り
Geometrical isomerization of arachidonic acid during lipid peroxidation interferes with ferroptosis

Yusuke Hirata, Carla Ferreri, Yuto Yamada, Aya Inoue, Anna Sansone, Fabrizio Vetica, Wakana Suzuki, Saya Takano, Takuya Noguchi, Atsushi Matsuzawa …

Free Radical Biology and Medicine 2023年5月査読有り責任著者
Reactive sulfur species disaggregate the SQSTM1/p62-based aggresome-like induced structures via the HSP70 induction and prevent parthanatos

Yutaro Yamada, Takuya Noguchi, Midori Suzuki, Mayuka Yamada, Yusuke Hirata, Atsushi Matsuzawa

Journal of Biological Chemistry 2023年4月13日査読有り最終著者責任著者
A comprehensive toxicological analysis of trans-fatty acids (TFAs) reveals a pro-apoptotic action specific to industrial TFAs counteracted by polyunsaturated FAs.

Yusuke Hirata, Naoki Kashiwabara, Yuki Nada, Aya Inoue, Emiko Sato, Takuya Noguchi, Atsushi Matsuzawa

Scientific Reports 13(1) 5883-5883 2023年4月11日査読有り最終著者責任著者
Lipid peroxidation increases membrane tension, Piezo1 gating, and cation permeability to execute ferroptosis

Yusuke Hirata, Ruiqi Cai, Allen Volchuk, Benjamin E. Steinberg, Yoshiro Saito, Atsushi Matsuzawa, Sergio Grinstein, Spencer A. Freeman

Current Biology 2023年3月査読有り
The NLRP3 Inflammasome Works as a Sensor for Detecting Hypoactivity of the Mitochondrial Src Family Kinases.

Yuto Sekiguchi, Saya Takano, Takuya Noguchi, Tomohiro Kagi, Ryuto Komatsu, Maoko Tan, Yusuke Hirata, Atsushi Matsuzawa

Journal of Immunology 2023年2月6日査読有り最終著者責任著者
SP600125 Enhances Temperature-Controlled Repeated Thermal Stimulation-Induced Neurite Outgrowth in PC12-P1F1 Cells

You-Ran Luo, Tada-aki Kudo, Kanako Tominami, Satoshi Izumi, Takakuni Tanaka, Yohei Hayashi, Takuya Noguchi, Atsushi Matsuzawa, Junichi Nakai, Guang Hong …

International Journal of Molecular Sciences 23(24) 15602-15602 2022年12月9日査読有り
The Distinct Roles of LKB1 and AMPK in p53-Dependent Apoptosis Induced by Cisplatin

Tatsuya Shimada, Yohsuke Yabuki, Takuya Noguchi, Mei Tsuchida, Ryuto Komatsu, Shuhei Hamano, Mayuka Yamada, Yusuke Ezaki, Yusuke Hirata, Atsushi Matsuzawa

International Journal of Molecular Sciences 23(17) 10064-10064 2022年9月2日査読有り最終著者責任著者
The polypeptide antibiotic polymyxin B acts as a pro-inflammatory irritant by preferentially targeting macrophages

Kagi, T., Naganuma, R., Inoue, A., Noguchi, T., Hamano, S., Sekiguchi, Y., Hwang, G. W., Hirata, Y., Matsuzawa, A.

The Journal of Antibiotics 75(1) 29-39 2022年2月査読有り最終著者責任著者
パータナトス誘導におけるカスパーゼ-3の新たな非典型的機能の関与

濱野修平, 鈴木碧, 平田祐介, 野口拓也, 松沢厚

日本毒性学会学術年会 49.1 P-75E 2022年
酸化ストレス誘導性パータナトスにおける活性硫黄の抑制効果

山田裕太郎, 鈴木碧, 平田祐介, 野口拓也, 松沢厚

日本毒性学会学術年会 49.1 P-67S 2022年
Deubiquitinase USP54 attenuates methylmercury toxicity in human embryonic kidney 293 cells

Jin-Yong Lee, Jong-Mu Kim, Takuya Noguchi, Atsushi Matsuzawa, Akira Naganuma, Gi-Wook Hwang

Fundamental Toxicological Sciences 9(5) 159-162 2022年査読有り
trans-Fatty acids promote p53-dependent apoptosis triggered by cisplatin-induced DNA interstrand crosslinks via the Nox-RIP1-ASK1-MAPK pathway

Hirata, Y., Takahashi, M., Yamada, Y., Matsui, R., Inoue, A., Ashida, R., Noguchi, T., Matsuzawa, A.

Scientific Reports 11(1) 10350 2021年6月査読有り最終著者責任著者
Methylmercury induces neuronal cell death by inducing TNF-α expression through the ASK1/p38 signaling pathway in microglia

Takashi Toyama, Takayuki Hoshi, Takuya Noguchi, Yoshiro Saito, Atsushi Matsuzawa, Akira Naganuma, Gi-Wook Hwang

Scientific Reports 11(1) 9832 2021年6月査読有り