Takashi Iwamoto

Profile Information

Affiliation: Department of Biomedical Sciences College of Life and Health Sciences CHUBU UNIVERSITY-
: (Concurrent)Center for Education in Laboratory Animal Research

J-GLOBAL ID: 201801017131369903
researchmap Member ID: B000336429

External link: https://www.chubu.ac.jp/about/faculty/profile/6322fcf3ae47743e17deca4b73899194b102cfe7.html

Research Areas

Papers

A Recql5 mutant facilitates complex CRISPR/Cas9-mediated-chromosomal engineering in mouse zygotes

Satoru Iwata, Miki Nagahara, Risako Ido, Takashi Iwamoto

GENETICS, Apr 5, 2024
A Recql5 mutant enables complex chromosomal engineering of mouse zygotes

Satoru Iwata, Miki Nagahara, Takashi Iwamoto

biorxiv, Apr 6, 2023
An efficient i-GONAD method for creating and maintaining lethal mutant mice using an inversion balancer identified from the C3H/HeJJcl strain

Satoru Iwata, Takahisa Sasaki, Miki Nagahara, Takashi Iwamoto

G3 Genes|Genomes|Genetics, 11(8), Jun 3, 2021
Forced expression of miR-143 and -145 in cardiomyocytes induces cardiomyopathy with a reductive redox shift

Kota Ogawa, Akiko Noda, Jun Ueda, Takehiro Ogata, Rumiko Matsuyama, Yuji Nishizawa, Shanlou Qiao, Satoru Iwata, Morihiro Ito, Yoshitaka Fujihara …

Cellular & Molecular Biology Letters, 25(1) 40-40, Dec, 2020
Simple and large-scale chromosomal engineering of mouse zygotes via in vitro and in vivo electroporation.

Iwata S, Nakadai H, Fukushi D, Jose M, Nagahara M, Iwamoto T

Scientific reports, 9(1) 14713-14713, Oct, 2019 Peer-reviewed
Classification of Cell Nuclei Using CNN Features

Iwahori Y, Tsukada Y, Iwamoto T, Funahashi K, Ueda J, Bhuyan MK

International Conference on Intelligence Science, 849 195-208, Sep, 2019 Peer-reviewed
Contour-Aware Residual W-Net for Nuclei Segmentation.

Das S, Deka A, Iwahori Y, Bhuyan MK, Iwamoto T, Ueda J

Procedia Computer Science, 159 1479-1488, Sep, 2019 Peer-reviewed
Classification of Benign or Malignant Cell Nuclei using Nucleolus.

Noriaki Kobayashi, Yuji Iwahori, Takashi Iwamoto, Jun Ueda, Boonserm Kijsirikul, Aili Wang 0001

8th International Congress on Advanced Applied Informatics(IIAI-AAI), 579-582, 2019
Extraction of Cell Nuclei using CNN Features

Tsukada Y, Iwahori Y, Funahashi K, Jose M, Ueda J, Iwamoto T

Procedia Computer Science, 112 1633-1640, Sep, 2017 Peer-reviewed
エレクトロポレーション法を用いたマウス受精卵のゲノム編集技術の確立

岩田悟, 仲臺瞳, 上瀬茉美, 長原美樹, 岩本隆司

中部大学生命健康科学研究所紀要, 14 92-96, 2017
Correspondence to Pasteurella pneumotropica infection: Application of oxidized water for clean-up operation.

Miki Nagahara, Ayumi Matsunaga, Yoshiaki Fujita, Mami Jose, Miyuki Ishisaka, Jun Ueda, Takashi Iwamoto

Annual Report of Research Institute of Life and Health Sciences, 12 92-95, Mar, 2016
Deficiency of DGCR8 gene, a potential gene for 22q11 deletion syndrome, decreases proliferation of neural stem cell in hippocampal dentate gyrus of adult mice

Yasuo Ouchi, Yuko Simizu, Shouta Ando, Mai Mizuno, Takashi Iwamoto

NEUROSCIENCE RESEARCH, 71 E75-E75, 2011
STAT and SMAD signaling in cancer

T Iwamoto, K Oshima, T Senga, Feng, X, ML Oo, M Hamaguchi, S Matsuda

HISTOLOGY AND HISTOPATHOLOGY, 17(3) 887-895, Jul, 2002
JAK/STAT3-dependent activation of the RalGDS/Ral pathway in M1 mouse myeloid leukemia cells

T Senga, T Iwamoto, T Kitamura, Y Miyake, M Hamaguchi

JOURNAL OF BIOLOGICAL CHEMISTRY, 276(35) 32678-32681, Aug, 2001
The JAK-inhibitor, JAB/SOCS-1 selectively inhibits cytokine-induced, but not v-Src induced JAK-STAT activation

T Iwamoto, T Senga, Y Naito, S Matsuda, Y Miyake, A Yoshimura, M Hamaguchi

ONCOGENE, 19(41) 4795-4801, Sep, 2000 Peer-reviewed
Transgenic mouse model for skin malignant melanoma

Masashi Kato, Masahide Takahashi, Anwarul A. Akhand, Wei Liu, Yan Dai, Satoru Shimizu, Takashi Iwamoto, Haruhiko Suzuki, Izumi Nakashima

Oncogene, 17(14) 1885-1888, Oct 8, 1998 Peer-reviewed
MULTIPHASIC MODULATION OF SIGNAL-TRANSDUCTION INTO T-LYMPHOCYTES BY MONOIODOACETIC ACID AS A SULFHYDRYL REAGENT

L MA, MY PU, AA AKHAND, N OHATA, K OHKUSU, M KATO, T IWAMOTO, K ISOBE, M HAMAGUCHI, NAKASHIMA, I

JOURNAL OF CELLULAR BIOCHEMISTRY, 59(1) 33-41, Sep, 1995 Peer-reviewed
Oncogene-linked in situ immunotherapy of pre-B lymphoma arising in E mu/ret transgenic mice.

Ichihara M, Iwamoto T, Isobe K, Takahashi M, Nakayama A, Pu M, Dai Y, Parashar A, Ohkus K, Kato M

British journal of cancer, 71(4) 808-813, Apr, 1995 Peer-reviewed
EVIDENCE FOR POSTTRANSCRIPTIONAL REGULATION OF TRANSGENIC PROTEIN-KINASE C-ALPHA IN T-CELLS

T IWAMOTO, K OHKUSU, M WATANABE, H HIDAKA, NAKASHIMA, I

JOURNAL OF CELLULAR BIOCHEMISTRY, 55(2) 264-271, Jun, 1994 Peer-reviewed
Pathway of signal delivery to murine thymocytes triggered by co-crosslinking CD3 and Thy-1 for cellular DNA fragmentation and growth inhibition.

I Nakashima, M Y Pu, M Hamaguchi, T Iwamoto, S M Rahman, Y H Zhang, M Kato, K Ohkusu, Y Katano, T Yoshida

Journal of immunology (Baltimore, Md. : 1950), 151(7) 3511-20, Oct 1, 1993

Misc.

低酸素環境におけるRET変異体の機能解析

喬善楼, 加藤智也, 小澄璃奈, 川本善之, 武田湖州恵, 市原正智, 岩本隆司

生命科学系学会合同年次大会, 2017年度 [1P-0600], Dec, 2017
マイクロRNA導入マウスに発症した拡張型心筋症における還元ストレスの解析

小川剛汰, 松山留美子, 喬善楼, 小形岳寛, 上田潤, 岩本隆司

日本生化学会大会(Web), 90th, 2017
22q11欠失症候群モデルマウスの神経発達障害にはCxcr4/Cxcl12シグナリングの欠損が寄与する

鳥塚通弘, 紀本創兵, 村木一枝, LANDEK‐SALGADO Melissa A, 吉田充裕, 山本典生, 堀内泰江, 比山英樹, 多神田勝規, 倪健偉 …

日本生物学的精神医学会誌, 458, 2014
Stat3 dependent RalGDS/Ral pathway is involved in LIF-induced mouse M1 leukemia cell differentiation to macrophage

T Senga, T Iwamoto, M Hamaguchi

MOLECULAR BIOLOGY OF THE CELL, 11 337A-337A, Dec, 2000
Stat3 dependent RalGDS/Ral pathway is involved in LIF-induced murine M1 leukemia cell differentiation to macrophage.

T Iwamoto, T Senga, Y Miyake, M Hamaguchi

BLOOD, 96(11) 681A-681A, Nov, 2000
Molecular cloning of a novel human gene (SIRP-B2) which encodes a new member of the SIRP/SHPS-1 protein family

Y Ichigotani, S Matsuda, K Machida, K Oshima, T Iwamoto, K Yamaki, T Hayakawa, M Hamaguchi

JOURNAL OF HUMAN GENETICS, 45(6) 378-382, 2000
CHARACTERIZATION OF THE IMMUNOREGULATORY ACTION OF SAIKOSAPONIN-D

M KATO, MY PU, KI ISOBE, T IWAMOTO, F NAGASE, T LWIN, YH ZHANG, T HATTORI, N YANAGITA, NAKASHIMA, I

CELLULAR IMMUNOLOGY, 159(1) 15-25, Nov, 1994
THE IL-3 AND GM-CSF RECEPTORS AND SIGNAL-TRANSDUCTION

A MIYAJIMA, A MUI, N SATO, K SAKAMAKI, T KINOSHITA, T KITAMURA, MIYAJIIMA, I, T IWAMOTO, T OGOROCHI, D GORMAN …

JOURNAL OF CELLULAR BIOCHEMISTRY, 3-3, Jan, 1994

Professional Memberships

Research Projects

新規miR-143/p38キナーゼ経路の生体での調節機構と乳癌細胞における解析

科学研究費助成事業, 基盤研究(C), 日本学術振興会, Apr, 2020 - Mar, 2023

岩本隆司, 喬善楼, 岩田悟
マイクロＲＮＡ導入マウス心筋症におけるヘキソキナーゼ２とMAS受容体シグナル解析

科学研究費基盤研(C), 文部科学省, Apr, 2016 - Mar, 2019

岩本隆司
Molecular hydrogen attenuates UV-induced tissue injury in Caenorhabditis elegans and mouse

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2012 - Mar, 2016

ICHIHARA Masatoshi, MURAKUMO Yoshiki, SOBUE Sayaka, IWAMOTO Takashi
マイクロRNA導入マウスにみられるアンジオテンシン変換酵素発現亢進と心不全の解析

科学研究費基盤研究（C), 文部科学省, Apr, 2013 - Mar, 2016

岩本隆司
遺伝子改変マウスにおけるマイクロRNAの抗腫瘍作用と心臓・平滑筋での機能の解析

科学研究費基盤研究（C), 文部科学省, Apr, 2010 - Mar, 2013

岩本隆司
Identification of downstream regulatory factor in RET signaling pathway and its application to cancer treatment

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2008 - 2010

ICHIHARA Masatoshi, IWAMOTO Takashi, QIAO Shanlou, MURAKUMO Yoshiki
Analysis of development and cancer in microRNA transgenic mice

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2007 - 2009

IWAMOTO Takashi, KATO Masashi, ICHIHARA Masatoshi
Regulatory System of Anchorage-Dependent Cell Growth

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, 2003 - 2005

HAMAGUCHI Michinari, IWAMOTO Takashi
足場依存増殖センサーの研究

科学研究費助成事業, 特定領域研究, 日本学術振興会, 2002 - 2003

浜口道成, 岩本隆司
Srcキナーゼによる癌細胞の足場非依存増殖と浸潤転移の制御機構

科学研究費助成事業, 特定領域研究, 日本学術振興会, 2002 - 2002

浜口道成, 岩本隆司
Trial of regeneration of retinal neuronal cells by myoseverin

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2001 - 2002

IWAMOTO Takashi, MIYAKE Yozo, HOMAGUCHI Michinari
v-src,v-crk癌化細胞の浸潤・転移に決定的なシグナル伝達系の研究

科学研究費助成事業, 特定領域研究(C), 日本学術振興会, 2001 - 2001

濱口道成, 岩本隆司
足場依存増殖センサーとしてのSHPS-1の研究

科学研究費助成事業, 特定領域研究(A), 日本学術振興会, 2001 - 2001

濱口道成, 岩本隆司
v-Src癌化細胞の浸潤・転移に決定的なシグナル伝達系の研究

科学研究費助成事業, 特定領域研究(C), 日本学術振興会, 2000 - 2000

浜口道成, 岩本隆司, 松田覚
Trial of cloning and functional analysis of a novel vascular endothelial growth factor.

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 1999 - 2000

IWAMOTO Takashi, ITO Masafumi, KITAMURA Toshio, MIYAKE Yozo, HAMAGUCHI Michinari
retがん遺伝子導入トランスジェニックマウスを用いた細胞がん化と転移に関する研究

科学研究費助成事業, がん特別研究, 日本学術振興会, 1992 - 1992

高橋雅英, 岩本隆司
がん遺伝子トランスジェニックマウス前がん段階の免疫調節による発がんの制御

科学研究費助成事業, がん特別研究, 日本学術振興会, 1991 - 1991

中島泉, 磯部健一, 岩本隆司

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