論文

査読有り
2008年11月

Capture of nonmagnetic particles and living cells using a microelectromagnetic system

JOURNAL OF APPLIED PHYSICS
  • Atsushi Aki
  • ,
  • Osamu Ito
  • ,
  • Hisao Morimoto
  • ,
  • Yutaka Nagaoka
  • ,
  • Yoshikata Nakajima
  • ,
  • Toru Mizuki
  • ,
  • Tatsuro Hanajiri
  • ,
  • Ron Usami
  • ,
  • Toru Maekawa

104
9
開始ページ
94509
終了ページ
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1063/1.3010307
出版者・発行元
AMER INST PHYSICS

We develop a microelectromagnetic system to trap nonmagnetic materials such as micropolystyrene particles and yeast cells in particular areas. We fabricate gold films, the width of the central narrow part is 22 mu m, and flow an electric current through the films. We then apply an external uniform dc magnetic field to weaken the local magnetic field at the narrow part so that a nonuniform magnetic field is produced. We demonstrate that the particles, which are dispersed in magnetic fluid, are successfully trapped at the narrow part of the film. We evaluate the driving force acting on a microparticle in the nonuniform magnetic field and carry out a Stokesian dynamics simulation of the motion of the particles. We show that yeast cells are also trapped at the narrow part of the film. Finally, we fabricate multichannel microelectromagnets so that yeast cells are trapped at multiple points in the microelectromagnetic system. The present system may be applied to cell transfection on a cell microarray and, therefore, eventually contribute to progress in the identification and determination technologies of different drug targets and the functions of genes and proteins. (C) 2008 American Institute of Physics. [DOI: 10.1063/1.3010307]

リンク情報
DOI
https://doi.org/10.1063/1.3010307
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000260941700123&DestApp=WOS_CPL
ID情報
  • DOI : 10.1063/1.3010307
  • ISSN : 0021-8979
  • Web of Science ID : WOS:000260941700123

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