2021年8月
Daily energy expenditure through the human life course
Science
- 巻
- 373
- 号
- 6556
- 開始ページ
- 808
- 終了ページ
- 812
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1126/science.abe5017
- 出版者・発行元
- AMER ASSOC ADVANCEMENT SCIENCE
Total daily energy expenditure ("total expenditure") reflects daily energy needs and is a critical variable in human health and physiology, but its trajectory over the life course is poorly studied. We analyzed a large, diverse database of total expenditure measured by the doubly labeled water method for males and females aged 8 days to 95 years. Total expenditure increased with fat-free mass in a power-law manner, with four distinct life stages. Fat-free mass-adjusted expenditure accelerates rapidly in neonates to ~50% above adult values at ~1 year; declines slowly to adult levels by ~20 years; remains stable in adulthood (20 to 60 years), even during pregnancy; then declines in older adults. These changes shed light on human development and aging and should help shape nutrition and health strategies across the life span.
- リンク情報
- ID情報
-
- DOI : 10.1126/science.abe5017
- ISSN : 1095-9203
- PubMed ID : 34385400
- PubMed Central 記事ID : PMC8370708