2018年4月1日
Treatment of premenstrual mood changes in a patient with schizophrenia using dienogest: A case report
Journal of Obstetrics and Gynaecology Research
- ,
- ,
- ,
- 巻
- 44
- 号
- 4
- 開始ページ
- 797
- 終了ページ
- 800
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1111/jog.13578
- 出版者・発行元
- Blackwell Publishing
Dienogest is a fourth-generation progestin that is used for the treatment of endometriosis. We report a case of premenstrual mood changes in a patient with schizophrenia who was unresponsive to conventional treatment but successfully managed with dienogest. A 37-year-old Japanese woman with schizophrenia was referred to our hospital and diagnosed with premenstrual exacerbation of schizophrenia or coexisting premenstrual dysphoric disorder with schizophrenia. She had already taken maximal doses of selective serotonin reuptake inhibitors and combined oral contraceptives produced intolerable side effects. Gonadotropin-releasing hormone agonist treatment was effective but was not suitable for long-term use. Dienogest was initiated to treat pelvic endometriosis and produced subsequent improvements in mental status. The patient was able to return to work and did not indicate any adverse effects. This case suggests that dienogest may be useful for managing premenstrual mood changes in patients with schizophrenia, that it can be safely administered over long periods of time.
- リンク情報
- ID情報
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- DOI : 10.1111/jog.13578
- ISSN : 1447-0756
- ISSN : 1341-8076
- eISSN : 1447-0756
- PubMed ID : 29359527
- SCOPUS ID : 85045114547
- Web of Science ID : WOS:000429557000026