Tomohiko Isobe

Profile Information

Affiliation: National Institute for Environmental Studies

J-GLOBAL ID: 200901059660382618
researchmap Member ID: 5000004206

Research Interests

Research Areas

Research History

Apr, 2021 - Present

Senior Researcher, Health and Environmental Risk Division, National Institute for Environmental Studies
May, 2014 - Mar, 2021

Senior Researcher, Center for Health and Environmental Risk Research, National Institute for Environmental Studies
Apr, 2013 - Apr, 2014

Associate Professor, Center for Marine Environmental Studies, Ehime University

Education

Apr, 1998 - Mar, 2001

Graduate School, Division of Agricltural Sciences, Tokyo University of Agriculture and Technology

Committee Memberships

2001 - 2018

水環境と洗剤研究委員会委員長, 日本水環境学会

Papers

Evaluating the risk of phthalate and non-phthalate plasticizers in dust samples from 100 Japanese houses.

Naohide Shinohara, Tomoko Oguri, Mai Takagi, Jun Ueyama, Tomohiko Isobe

Environment international, 183 108399-108399, Jan, 2024
Concentrations of neonicotinoid insecticides and their metabolites in multiple urine samples collected from pregnant women in Japan

Neeranuch Suwannarin, Tomohiko Isobe, Yukiko Nishihama, Yuki Ito, Michihiro Kamijima, Takeshi Ebara, Mayumi Sugiura-Ogasawara, Naomi Nishikawa, Kunihiko Nakai, Yumina Minamikawa …

Environmental Research, 240 117506-117506, Jan, 2024
Association between maternal urinary neonicotinoid concentrations and child development in the Japan Environment and Children's Study.

Yukiko Nishihama, Shoji F Nakayama, Tomohiko Isobe, Michihiro Kamijima

Environment international, 181 108267-108267, Oct 13, 2023
Pharmaceuticals and personal care products (PPCPs) in surface water and fish from three Asian countries: Species-specific bioaccumulation and potential ecological risks

Kazusa Nozaki, Rumi Tanoue, Tatsuya Kunisue, Nguyen Minh Tue, Sadahiko Fujii, Nao Sudo, Tomohiko Isobe, Kei Nakayama, Agus Sudaryanto, Annamalai Subramanian …

Science of The Total Environment, 866 161258-161258, Mar, 2023
A simultaneous, high-throughput and sensitive method for analysing 13 neonicotinoids and metabolites in urine using a liquid chromatography-tandem mass spectrometry.

Yukiko Nishihama, Shoji F Nakayama, Tomohiko Isobe

MethodsX, 10 102129-102129, 2023
Effects of Pesticide Intake on Gut Microbiota and Metabolites in Healthy Adults.

Jun Ueyama, Mai Hayashi, Masaaki Hirayama, Hiroshi Nishiwaki, Mikako Ito, Isao Saito, Yoshio Tsuboi, Tomohiko Isobe, Kinji Ohno

International journal of environmental research and public health, 20(1), Dec 23, 2022
Health Risk Assessment Based on Exposure to Chemicals in Air

Hironari Sakamoto, Shigehisa Uchiyama, Ayana Sato, Tomohiko Isobe, Naoki Kunugita, Hironao Ogura, Shoji F. Nakayama

International Journal of Environmental Research and Public Health, 19(23) 15813-15813, Nov 28, 2022
Optimal method for determining the intraclass correlation coefficients of urinary biomarkers such as dialkylphosphates from imputed data.

Yukiko Nishihama, Yonghang Lai, Tomohiko Isobe, Shoji F Nakayama

Environment international, 170 107553-107553, Sep 28, 2022
Baseline Complete Blood Count and Chemistry Panel Profile from the Japan Environment and Children's Study (JECS).

Yu Taniguchi, Shin Yamazaki, Shoji F Nakayama, Makiko Sekiyama, Takehiro Michikawa, Tomohiko Isobe, Miyuki Iwai-Shimada, Yayoi Kobayashi, Mai Takagi, Michihiro Kamijima …

International journal of environmental research and public health, 19(6), Mar 10, 2022
Spatial Variations of Indoor Air Chemicals in an Apartment Unit and Personal Exposure of Residents.

Hironari Sakamoto, Shigehisa Uchiyama, Tomohiko Isobe, Naoki Kunugita, Hironao Ogura, Shoji F Nakayama

International journal of environmental research and public health, 18(21), Nov 1, 2021
Association of prenatal exposure to cadmium with neurodevelopment in children at 2 years of age: The Japan Environment and Children’s Study

Chaochen Ma, Miyuki Iwai-Shimada, Shoji F. Nakayama, Tomohiko Isobe, Yayoi Kobayashi, Nozomi Tatsuta, Yu Taniguchi, Makiko Sekiyama, Takehiro Michikawa, Shin Yamazaki …

Environment International, 156 106762-106762, Nov, 2021
Association between Haematological Parameters and Exposure to a Mixture of Organophosphate and Neonicotinoid Insecticides among Male Farmworkers in Northern Thailand.

Neeranuch Suwannarin, Tippawan Prapamontol, Tomohiko Isobe, Yukiko Nishihama, Ampica Mangklabruks, Tawiwan Pantasri, Somporn Chantara, Warangkana Naksen, Shoji F Nakayama

International journal of environmental research and public health, 18(20), Oct 15, 2021
Defining the Scope of Exposome Studies and Research Needs from a Multidisciplinary Perspective

Pei Zhang, Christopher Carlsten, Romanas Chaleckis, Kati Hanhineva, Mengna Huang, Tomohiko Isobe, Ville M. Koistinen, Isabel Meister, Stefano Papazian, Kalliroi Sdougkou …

ENVIRONMENTAL SCIENCE & TECHNOLOGY LETTERS, 8(10) 839-852, Oct, 2021
Urinary Metabolites of Organophosphate Pesticides among Pregnant Women Participating in the Japan Environment and Children's Study (JECS)

Yukiko Nishihama, Shoji F. Nakayama, Tomohiko Isobe, Chau-Ren Jung, Miyuki Iwai-Shimada, Yayoi Kobayashi, Takehiro Michikawa, Makiko Sekiyama, Yu Taniguchi, Shin Yamazaki

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 18(11), Jun, 2021
Exposure to Organophosphate and Neonicotinoid Insecticides and Its Association with Steroid Hormones among Male Reproductive-Age Farmworkers in Northern Thailand

Neeranuch Suwannarin, Tippawan Prapamontol, Tomohiko Isobe, Yukiko Nishihama, Yuki Hashimoto, Ampica Mangklabruks, Tawiwan Pantasri, Somporn Chantara, Warangkana Naksen, Shoji F. Nakayama

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 18(11), Jun, 2021
Indoor air quality of 5,000 households and its determinants. Part A: Particulate matter (PM2.5 and PM10-2.5) concentrations in the Japan Environment and Children's Study.

Yukiko Nishihama, Chau-Ren Jung, Shoji F Nakayama, Kenji Tamura, Tomohiko Isobe, Takehiro Michikawa, Miyuki Iwai-Shimada, Yayoi Kobayashi, Makiko Sekiyama, Yu Taniguchi …

Environmental research, 198 111196-111196, Apr 30, 2021
Comparison of Simultaneous Quantitative Analysis of Methylmercury and Inorganic Mercury in Cord Blood Using LC-ICP-MS and LC-CVAFS: The Pilot Study of the Japan Environment and Children's Study.

Miyuki Iwai-Shimada, Yayoi Kobayashi, Tomohiko Isobe, Shoji F Nakayama, Makiko Sekiyama, Yu Taniguchi, Shin Yamazaki, Takehiro Michikawa, Masako Oda, Hiroshi Mitsubuchi …

Toxics, 9(4), Apr 9, 2021
Indoor air quality of 5,000 households and its determinants. Part B: Volatile organic compounds and inorganic gaseous pollutants in the Japan Environment and Children’s Study

Chau-Ren Jung, Yukiko Nishihama, Shoji F. Nakayama, Kenji Tamura, Tomohiko Isobe, Takehiro Michikawa, Miyuki Iwai-Shimada, Yayoi Kobayashi, Makiko Sekiyama, Yu Taniguchi …

Environmental Research, 111135-111135, Apr, 2021
Anthropogenic and natural organohalogen compounds in melon-headed whales (Peponocephala electra) stranded along the Japanese coastal waters: Temporal trend analysis using archived samples in the environmental specimen bank (es-BANK).

Tatsuya Kunisue, Akitoshi Goto, Tomoya Sunouchi, Kana Egashira, Mari Ochiai, Tomohiko Isobe, Yuko Tajima, Tadasu K Yamada, Shinsuke Tanabe

Chemosphere, 269 129401-129401, Apr, 2021
Association of prenatal maternal blood lead levels with birth outcomes in the Japan Environment and Children’s Study (JECS): a nationwide birth cohort study

Yoshihito Goto, Marie Mandai, Takeo Nakayama, Shin Yamazaki, Shoji F Nakayama, Tomohiko Isobe, Tosiya Sato, Hiroshi Nitta

International Journal of Epidemiology, 50(1) 156-164, Mar 3, 2021

Misc.

Suspected phenolic endocrine-disrupting compounds in human urine and exposure media: estimation of exposure levels and excretion rates

大浦奏, 田上瑠美, 上山純, 小栗朋子, 磯部友彦, 国末達也

環境化学討論会要旨集(CD-ROM), 30th, 2022
Intervention trials with controlled diet and use of personal care products to reveal the pharmacokinetics of chemicals

磯部友彦, 中山祥嗣, 岩井美幸, 高木麻衣, 上山純, 小栗朋子, 篠原直秀, 国末達也, 仲山慶, 田上瑠美

環境化学討論会要旨集(CD-ROM), 30th, 2022
Basic study on measurement method for phthalate alternative metabolites in urine

小栗朋子, 篠原直秀, 高木麻衣, 上山純, 国末達也, 磯部友彦

環境化学討論会要旨集(CD-ROM), 30th, 2022
Phthalates and Phthalate Alternatives in House Dust-DINCH and DEHA-

篠原直秀, 小栗朋子, 高木麻衣, 上山純, 磯部友彦

環境化学討論会要旨集(CD-ROM), 30th, 2022
Suspected phenolic endocrine-disrupting compounds in human urine and personal care products: levels, variation, and exposure assessment

大浦奏, 田上瑠美, 上山純, 小栗朋子, 磯部友彦, 国末達也

環境ホルモン学会研究発表会プログラム・要旨集, 23rd (Web), 2021
ChemTHEATREとAIST-MeRAMの統合利用による化学物質のリスク評価

仲山慶, LIN Bin-Le, 磯部友彦, 宇野誠一, 大野暢亮, 半藤逸樹, 国末達也

環境化学討論会要旨集(CD-ROM), 28th, 2019
ChemTHEATREによる環境中の化学物質モニタリング情報のオープンデータ化~その重要性と課題~

仲山慶, 国末達也, 磯部友彦, 半藤逸樹, 宇野誠一, 大野暢亮

日本水環境学会年会講演集, 53rd, 2019
一般家庭における重金属曝露メカニズムの解明調査プロトコルについて

西浜柚季子, 龍田希, 岩井美幸, 磯部友彦, 藤原幾磨, 有馬隆博, 中山祥嗣, 和泉孝志, 仲井邦彦

日本衛生学雑誌, 73(Suppl.) S272-S272, Mar, 2018
一般家庭における重金属曝露メカニズムの解明調査プロトコルについて

西浜柚季子, 龍田希, 岩井美幸, 磯部友彦, 藤原幾磨, 有馬隆博, 中山祥嗣, 和泉孝志, 仲井邦彦

日本衛生学雑誌, 73(Suppl.) S272-S272, Mar, 2018
環境中の化学物質濃度情報を管理するプラットフォーム「ChemTHEATRE」の機能拡張とメタデータ利活用の基盤整備

仲山慶, 磯部友彦, 宇野誠一, 大野暢亮, 半藤逸樹, 国末達也

環境化学討論会要旨集(CD-ROM), 27th, 2018
環境モニタリングデータのためのオープンデータプラットフォーム「ChemTHEATRE」

磯部友彦, 仲山慶, 宇野誠一, 大野暢亮, 半藤逸樹, 国末達也

日本内分泌かく乱化学物質学会研究発表会要旨集, 21st, 2018
底質中環境汚染物質のノンターゲット分析-試料の網羅的解析と精密質量スペクトルデータベースの構築-

家田曜世, 橋本俊次, 磯部友彦, 高澤嘉一, 田邊潔, 国末達也, 田辺信介

環境化学討論会要旨集(CD-ROM), 26th, 2017
環境中の化学物質濃度情報を管理するプラットフォーム「ChemTHEATRE」の利活用

仲山慶, 磯部友彦, 宇野誠一, 大野暢晃, 半藤逸樹, 上野大介, 国末達也

環境化学討論会要旨集(CD-ROM), 26th, 2017
環境モニタリング情報のデータベース化~ChemTHEATREの取り組みと課題~

仲山慶, 国末達也, 磯部友彦, 半藤逸樹, 宇野誠一, 大野暢晃

日本水環境学会シンポジウム講演集, 20th, 2017
モニタリングデータの有効活用~環境中の化学物質濃度データベース「ChemTHEATRE」の構築~

磯部友彦, 仲山慶, 国末達也, 宇野誠一, 半藤逸樹, 大野暢晃

日本水環境学会シンポジウム講演集, 19th 42, Sep 13, 2016
環境中の化学物質濃度情報を管理するプラットフォーム「ChemTHEATRE」の構築

仲山慶, 磯部友彦, 宇野誠一, 大野暢晃, 半藤逸樹, 国末達也

環境化学討論会要旨集(CD-ROM), 25th ROMBUNNO.P‐029, Jun 6, 2016
尿中有機リン系殺虫剤代謝物測定の個人間変動と施設間差についての検討

伊藤由起, 上山純, 中山祥嗣, 磯部友彦, 佐藤博貴, 大矢奈穂子, 仲井邦彦, 上島通浩

日本衛生学雑誌(Web), 71(Supplement) S213-S213, May, 2016
生体試料中ネオニコチノイド系農薬の分析

磯部友彦, 佐野一広, 吉兼光葉, 鈴木剛, SHWE Tin Tin Win, 橋本俊次, 川嶋貴治, 前川文彦, 中山祥嗣

環境化学討論会要旨集(CD-ROM), 25th, 2016
GC×GC-HRTOFMSによる多成分網羅分析-ソフトウェアによる化合物の自動検出とマトリックスの影響評価-

家田曜世, 橋本俊次, 高澤嘉一, 田邊潔, 頭士泰之, 柴田康行, 前川文彦, 佐野一広, 鈴木剛, 中山祥嗣 …

環境化学討論会要旨集(CD-ROM), 25th, 2016
環境中化学物質の濃度情報に関するデータベース「ChemTHEATRE」によるモニタリング情報の管理と活用

磯部友彦, 仲山慶, 宇野誠一, 大野暢晃, 半藤逸樹, 国末達也

日本内分泌かく乱化学物質学会研究発表会要旨集, 19th, 2016

Professional Memberships

Research Projects

To Evaluate positive correlation between bio-accumulation of POPs and pathological significant changes using stranded cetaceans in Japan.

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2013 - Mar, 2017

TAJIMA YUKO, YAMADA TADASU, ISOBE TOMOHIKO
Contamination status of organohalogen compounds and their metabolites of pet animals and effects on thyroid hormones homeostasis

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (A), Grant-in-Aid for Scientific Research (A), Japan Society for the Promotion of Science, Apr, 2013 - Mar, 2016

TANABE SHINSUKE, IWATA Hisato, NOMIYAMA Kei, KUNISUE Tatsuya
Contamination status and spatiotemporal distribution of novel and candidate POPs in Asian regions

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (A), Grant-in-Aid for Scientific Research (A), Japan Society for the Promotion of Science, Apr, 2013 - Mar, 2016

TANABE SHINSUKE, KUNISUE TATSUYA, TAKAHASHI SHIN, ISOBE TOMOHIKO
Levels and temporal trends of brominated flame retardants and organochlorine POPs

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B), Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2013 - Mar, 2016

Isobe Tomohiko, TAJIMA YUKO, YAMADA TADASU, MATSUISHI TAKASHI, AMANO MASAO, KUNISUE TATSUYA
Searching and risk assessment for indoor persistent chemicals -Use of companion animals as the indicators-

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B), Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2013 - Mar, 2016

KUNISUE TATSUYA, OKAMOTO YOSHIHARU, SUZUKI GO, HORAI SAWAKO, ISOBE TOMOHIKO
Evaluation of Temporal Variation in Levels of Persistent Organic Pollutants and Trace Elements in Marine Ecosystem of Off-Tohoku after Great East Japan Earthquake

Grants-in-Aid for Scientific Research Grant-in-Aid for Challenging Exploratory Research, Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, Apr, 2012 - Mar, 2015

TANABE Shinsuke, ISOBE Tomohiko, ITAI Takaaki
Bioaccumulation of Halogenated and Non-halogenated Flame Retardants through Marine Food Web

Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B), Grant-in-Aid for Young Scientists (B), Japan Society for the Promotion of Science, 2011 - 2012

ISOBE Tomohiko
Environmental Contamination and Ecological Risk of Novel POPs in the Asian Developing Region

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (S), Grant-in-Aid for Scientific Research (S), Japan Society for the Promotion of Science, 2008 - 2012

TANABE Shinsuke, IWATA Hisato, TAKASUGA Takumi, TAKAHASHI Shin, NAKAYAMA Kei, TAKIGAMI Hidetaka, ISOBE Tomohiko, SUZUKI Go
Evaluation of trophic magnification and ecological risk of persistent toxic substances by integration of bio-geochemistry and numerical analysis

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B), Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, 2009 - 2011

TAKAHASHI Shin, ISOBE Tomohiko, KOJI Omori, ITSUKI Handoh
Environmental pollution by new brominated flame retardants

Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B), Grant-in-Aid for Young Scientists (B), Japan Society for the Promotion of Science, 2007 - 2008

ISOBE Tomohiko
Specific accumulation, metabolism and potential effects of persistent organohalogen compounds in predatory wild animals

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B), Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, 2006 - 2008

TAKAHASHI Shin, TANABE Shinsuke, IWATA Hisato, ISOBE Tomohiko, TAKIGAMI Hidetaka, KUNISUE Tatsuya, SUZUKI Go

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