論文

国際誌
2021年5月24日

All-dielectric chiral-field-enhanced Raman optical activity.

Nature communications
  • Ting-Hui Xiao
  • ,
  • Zhenzhou Cheng
  • ,
  • Zhenyi Luo
  • ,
  • Akihiro Isozaki
  • ,
  • Kotaro Hiramatsu
  • ,
  • Tamitake Itoh
  • ,
  • Masahiro Nomura
  • ,
  • Satoshi Iwamoto
  • ,
  • Keisuke Goda

12
1
開始ページ
3062
終了ページ
3062
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1038/s41467-021-23364-w

Raman optical activity (ROA) is effective for studying the conformational structure and behavior of chiral molecules in aqueous solutions and is advantageous over X-ray crystallography and nuclear magnetic resonance spectroscopy in sample preparation and cost performance. However, ROA signals are inherently minuscule; 3-5 orders of magnitude weaker than spontaneous Raman scattering due to the weak chiral light-matter interaction. Localized surface plasmon resonance on metallic nanoparticles has been employed to enhance ROA signals, but suffers from detrimental spectral artifacts due to its photothermal heat generation and inability to efficiently transfer and enhance optical chirality from the far field to the near field. Here we demonstrate all-dielectric chiral-field-enhanced ROA by devising a silicon nanodisk array and exploiting its dark mode to overcome these limitations. Specifically, we use it with pairs of chemical and biological enantiomers to show >100x enhanced chiral light-molecule interaction with negligible artifacts for ROA measurements.

リンク情報
DOI
https://doi.org/10.1038/s41467-021-23364-w
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/34031409
PubMed Central
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144208
ID情報
  • DOI : 10.1038/s41467-021-23364-w
  • ORCIDのPut Code : 94334442
  • PubMed ID : 34031409
  • PubMed Central 記事ID : PMC8144208

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