1999年9月1日
G-CSF産生上顎癌例
耳鼻咽喉科臨床
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- 巻
- 92
- 号
- 9
- 開始ページ
- 987
- 終了ページ
- 992
- 記述言語
- 日本語
- 掲載種別
- DOI
- 10.5631/jibirin.92.987
- 出版者・発行元
- 耳鼻咽喉科臨床学会
A 64-year-old man with well-differentiated squamous cell carcinoma of the maxilla who presented with high levels of granulocyte-colony stimulating factor (G-CSF) is described. The extent of the tumor was staged as T4N1M0. Regional chemotherapy, radiotherapy and resection of the tumor were performed. The patient died of local recurrence and lung metastasis about four months after admission. During his clinical course, a peripheral blood analysis demonstrated marked granulocytosis and high G-CSF activity. G-CSF producing cancer cells were immunohistologically observed in the primary lesion and metastatic lymph nodes. Therefore, he was diagnosed with G-CSF producing maxillary cancer. The cancer tissue from this patient was transplanted into nude mice, and one of these mice demonstrated distant metastasis to the lung.
- リンク情報
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- DOI
- https://doi.org/10.5631/jibirin.92.987
- CiNii Articles
- http://ci.nii.ac.jp/naid/10005266301
- CiNii Books
- http://ci.nii.ac.jp/ncid/AN00107089
- ID情報
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- DOI : 10.5631/jibirin.92.987
- ISSN : 0032-6313
- CiNii Articles ID : 10005266301
- CiNii Books ID : AN00107089